Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse.
Hay CE, Gonzalez GA 3rd, Ewing LE, Reichard EE, Hambuchen MD, Nanaware-Kharade N, Alam S, Bolden CT, Owens SM, Margaritis P, Peterson EC.
Hay CE, et al.
PLoS One. 2018 Jun 29;13(6):e0200060. doi: 10.1371/journal.pone.0200060. eCollection 2018.
PLoS One. 2018.
PMID: 29958300
Free PMC article.
An adeno-associated viral (AAV)-delivered DNA sequence for a single-chain variable fragment could offer long-term, continuous expression of anti-METH antibody fragments. For these studies, we injected mice via tail vein with 1 x 10(12) vector genomes of two AAV8 scFv const …
An adeno-associated viral (AAV)-delivered DNA sequence for a single-chain variable fragment could offer long-term, continuous express …