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Developmental Associations between Neurovascularization and Microglia Colonization.
Harry GJ. Harry GJ. Int J Mol Sci. 2024 Jan 20;25(2):1281. doi: 10.3390/ijms25021281. Int J Mol Sci. 2024. PMID: 38279280 Free PMC article. Review.
Additionally, such knowledge should provide a framework for understanding the influence of the early gestational environmental and the impact of genetics, disease, disorders, or exposures on the early developing nervous system and the potential for long-term and life-time …
Additionally, such knowledge should provide a framework for understanding the influence of the early gestational environmental and the impac …
Microglia in the developing brain: a potential target with lifetime effects.
Harry GJ, Kraft AD. Harry GJ, et al. Neurotoxicology. 2012 Mar;33(2):191-206. doi: 10.1016/j.neuro.2012.01.012. Epub 2012 Feb 2. Neurotoxicology. 2012. PMID: 22322212 Free PMC article. Review.
., vascularization, synaptogenesis, and myelination) and have a long term impact on the functional vulnerability of the nervous system to a subsequent insult, whether environmental, physical, age-related, or disease-related....
., vascularization, synaptogenesis, and myelination) and have a long term impact on the functional vulnerability of the nervous syste …
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Thébaud B, Michelakis ED, Archer SL. Kajimoto H, et al. Among authors: harry g. Circulation. 2007 Apr 3;115(13):1777-88. doi: 10.1161/CIRCULATIONAHA.106.649566. Epub 2007 Mar 12. Circulation. 2007. PMID: 17353442
BACKGROUND: Constriction of the ductus arteriosus (DA) is initiated at birth by inhibition of O2-sensitive K+ channels in DA smooth muscle cells. ...CONCLUSIONS: O2 activates Rho-kinase and increases Rho-kinase expression in term DA smooth muscle cells by a redox-re …
BACKGROUND: Constriction of the ductus arteriosus (DA) is initiated at birth by inhibition of O2-sensitive K+ channels in DA smooth m …
Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeks.
Morgan DL, Little PB, Herr DW, Moser VC, Collins B, Herbert R, Johnson GA, Maronpot RR, Harry GJ, Sills RC. Morgan DL, et al. Among authors: harry gj. Toxicol Appl Pharmacol. 2004 Oct 15;200(2):131-45. doi: 10.1016/j.taap.2004.04.013. Toxicol Appl Pharmacol. 2004. PMID: 15476866
Carbonyl sulfide (COS), a high-priority Clean Air Act chemical, was evaluated for neurotoxicity in short-term studies. F344 rats were exposed to 75-600 ppm COS 6 h per day, 5 days per week for up to 12 weeks. ...
Carbonyl sulfide (COS), a high-priority Clean Air Act chemical, was evaluated for neurotoxicity in short-term studies. F344 rats were …
Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels.
Thébaud B, Michelakis E, Wu XC, Harry G, Hashimoto K, Archer SL. Thébaud B, et al. Among authors: harry g. Pediatr Res. 2002 Jul;52(1):19-24. doi: 10.1203/00006450-200207000-00006. Pediatr Res. 2002. PMID: 12084842
Oxygen constriction causes functional closure of the ductus arteriosus (DA) at birth. Although DA closure is crucial for postnatal adaptation, patency of the DA is critical for survival of newborns with duct-dependent cardiac malformations. ...We hypothesized that sildenaf …
Oxygen constriction causes functional closure of the ductus arteriosus (DA) at birth. Although DA closure is crucial for postnatal ad …
Postpartum exposure to triethyl tin produces long-term alterations in responsiveness to apomorphine.
Harry GJ, Tilson HA. Harry GJ, et al. Neurotoxicology. 1982 Jul;3(1):64-71. Neurotoxicology. 1982. PMID: 6890190
The present data are in accord with the hypothesis that one of the long-term consequences of neonatal exposure to TET might be an alteration in the responsiveness of the dopamine system....
The present data are in accord with the hypothesis that one of the long-term consequences of neonatal exposure to TET might be an alt …
The effects of postpartum exposure to triethyl tin on the neurobehavioral functioning of rats.
Harry GJ, Tilson HA. Harry GJ, et al. Neurotoxicology. 1981 Oct;2(2):283-96. Neurotoxicology. 1981. PMID: 7198757
Activity during the intertrial interval was not affected. A single postnatal exposure to TET can produce long-term alterations in the sensorimotor capabilities of rats; the effect appears to occur equally in both sexes and is independent of toxicant-induced body weight cha …
Activity during the intertrial interval was not affected. A single postnatal exposure to TET can produce long-term alterations in the …