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Timing and burden of persistent critical illnessin UK intensive care units: An observational cohort study.
Harrison DA, Creagh-Brown BC, Rowan KM. Harrison DA, et al. J Intensive Care Soc. 2023 May;24(2):139-146. doi: 10.1177/17511437211047180. Epub 2021 Nov 5. J Intensive Care Soc. 2023. PMID: 37260430 Free PMC article.
CONCLUSIONS: Persistent critical illness is commonly encountered in clinical practice and is associated with increased healthcare utilisation and adverse outcomes. Improvements in our understanding of the longer term outcomes and in the development of tools to aid prognost …
CONCLUSIONS: Persistent critical illness is commonly encountered in clinical practice and is associated with increased healthcare utilisatio …
Improving risk prediction model quality in the critically ill: data linkage study [Internet].
Ferrando-Vivas P, Shankar-Hari M, Thomas K, Doidge JC, Caskey FJ, Forni L, Harris S, Ostermann M, Gornik I, Holman N, Lone N, Young B, Jenkins D, Webb S, Nolan JP, Soar J, Rowan KM, Harrison DA. Ferrando-Vivas P, et al. Among authors: harrison da. Southampton (UK): National Institute for Health and Care Research; 2022 Dec. Southampton (UK): National Institute for Health and Care Research; 2022 Dec. PMID: 36542744 Free Books & Documents. Review.
Second, to improve risk models for cardiothoracic critical care by enhancing risk factor data and developing models for longer-term mortality. Third, to improve risk models for in-hospital cardiac arrest by enhancing risk factor data and developing models for longer-ter …
Second, to improve risk models for cardiothoracic critical care by enhancing risk factor data and developing models for longer-term m …
Renal replacement anticoagulant management: Protocol and analysis plan for an observational comparative effectiveness study of linked data sources.
Gould DW, Doidge J, Zia Sadique M, Borthwick M, Caskey FJ, Forni L, Lawrence RF, MacEwen C, Mouncey PR, Ostermann M, Harrison DA, Rowan KM, Duncan Young J, Watkinson PJ. Gould DW, et al. Among authors: harrison da. J Intensive Care Soc. 2022 Aug;23(3):311-317. doi: 10.1177/1751143720913417. Epub 2020 Apr 2. J Intensive Care Soc. 2022. PMID: 36033243 Free PMC article.
This shift towards regional citrate anticoagulation for CRRT is occurring with little evidence of safety or longer term effectiveness. Renal replacement anticoagulant management (RRAM) is an observational comparative effectiveness study, utilising existing data sources to …
This shift towards regional citrate anticoagulation for CRRT is occurring with little evidence of safety or longer term effectiveness …
New-onset atrial fibrillation in intensive care: epidemiology and outcomes.
Bedford JP, Ferrando-Vivas P, Redfern O, Rajappan K, Harrison DA, Watkinson PJ, Doidge JC. Bedford JP, et al. Among authors: harrison da. Eur Heart J Acute Cardiovasc Care. 2022 Aug 9;11(8):620-628. doi: 10.1093/ehjacc/zuac080. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 35792651 Free PMC article.
AIMS: New-onset atrial fibrillation (NOAF) is common in patients treated on an intensive care unit (ICU), but the long-term impacts on patient outcomes are unclear. We compared national hospital and long-term outcomes of patients who developed NOAF in ICU with those …
AIMS: New-onset atrial fibrillation (NOAF) is common in patients treated on an intensive care unit (ICU), but the long-term impacts o …
Heparin versus citrate anticoagulation for continuous renal replacement therapy in intensive care: the RRAM observational study.
Gould DW, Doidge J, Sadique MZ, Borthwick M, Hatch R, Caskey FJ, Forni L, Lawrence RF, MacEwen C, Ostermann M, Mouncey PR, Harrison DA, Rowan KM, Young JD, Watkinson PJ. Gould DW, et al. Among authors: harrison da. Health Technol Assess. 2022 Feb;26(13):1-58. doi: 10.3310/ZXHI9396. Health Technol Assess. 2022. PMID: 35212260 Free PMC article.
We used routinely collected data from the Intensive Care National Audit & Research Centre Case Mix Programme national clinical audit to identify 69,001 patients who received continuous renal replacement therapy in an intensive care unit in England or Wales between 1 April 200 …
We used routinely collected data from the Intensive Care National Audit & Research Centre Case Mix Programme national clinical audit to …
Children's Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial.
Kiguli S, Olopot-Olupot P, Alaroker F, Engoru C, Opoka RO, Tagoola A, Hamaluba M, Mnjalla H, Mpoya A, Mogaka C, Nalwanga D, Nabawanuka E, Nokes J, Nyaigoti C, Briend A, van Woensel JBM, Grieve R, Sadique Z, Williams TN, Thomas K, Harrison DA, Rowan K, Maitland K. Kiguli S, et al. Among authors: harrison da. Wellcome Open Res. 2021 Oct 18;6:221. doi: 10.12688/wellcomeopenres.17123.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 34734123 Free PMC article.
Background: To prevent poor long-term outcomes (deaths and readmissions) the integrated global action plan for pneumonia and diarrhoea recommends under the 'Treat' element of Protect, Prevent and Treat interventions the importance of continued feeding but gives no specific …
Background: To prevent poor long-term outcomes (deaths and readmissions) the integrated global action plan for pneumonia and diarrhoe …
Realising the full potential of data-enabled trials in the UK: a call for action.
Sydes MR, Barbachano Y, Bowman L, Denwood T, Farmer A, Garfield-Birkbeck S, Gibson M, Gulliford MC, Harrison DA, Hewitt C, Logue J, Navaie W, Norrie J, O'Kane M, Quint JK, Rycroft-Malone J, Sheffield J, Smeeth L, Sullivan F, Tizzard J, Walker P, Wilding J, Williamson PR, Landray M, Morris A, Walker RR, Williams HC, Valentine J; Data Enabled Trials Group Workshop Group members. Sydes MR, et al. Among authors: harrison da. BMJ Open. 2021 Jun 16;11(6):e043906. doi: 10.1136/bmjopen-2020-043906. BMJ Open. 2021. PMID: 34135032 Free PMC article. Review.
DISCUSSION: EHR offer opportunities to better plan clinical trials, assess patients and capture data more efficiently, reducing research waste and increasing focus on each trial's specific challenges. The short-term emphasis should be on facilitating patient recruitment an …
DISCUSSION: EHR offer opportunities to better plan clinical trials, assess patients and capture data more efficiently, reducing research was …
Development, Validation, and Clinical Utility Assessment of a Prognostic Score for 1-Year Unplanned Rehospitalization or Death of Adult Sepsis Survivors.
Shankar-Hari M, Rubenfeld GD, Ferrando-Vivas P, Harrison DA, Rowan K. Shankar-Hari M, et al. Among authors: harrison da. JAMA Netw Open. 2020 Sep 1;3(9):e2013580. doi: 10.1001/jamanetworkopen.2020.13580. JAMA Netw Open. 2020. PMID: 32926114 Free PMC article.
IMPORTANCE: The longer-term risk of rehospitalizations and death of adult sepsis survivors is associated with index sepsis illness characteristics. ...
IMPORTANCE: The longer-term risk of rehospitalizations and death of adult sepsis survivors is associated with index sepsis illness ch …
Does delaying discharge from intensive care until after tracheostomy removal affect 30-day mortality? Propensity score matched cohort study.
Vollam S, Harrison DA, Young JD, Watkinson PJ. Vollam S, et al. Among authors: harrison da. BMJ Open. 2020 Jun 7;10(6):e037762. doi: 10.1136/bmjopen-2020-037762. BMJ Open. 2020. PMID: 32513895 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate the short-term mortality effect of discharge from an intensive care unit (ICU) with a tracheostomy in place in comparison to delaying discharge until after tracheostomy removal. ...
OBJECTIVE: To investigate the short-term mortality effect of discharge from an intensive care unit (ICU) with a tracheostomy in place …
Interventions to reduce Staphylococcus aureus in the management of eczema.
George SM, Karanovic S, Harrison DA, Rani A, Birnie AJ, Bath-Hextall FJ, Ravenscroft JC, Williams HC. George SM, et al. Among authors: harrison da. Cochrane Database Syst Rev. 2019 Oct 29;2019(10):CD003871. doi: 10.1002/14651858.CD003871.pub3. Cochrane Database Syst Rev. 2019. PMID: 31684694 Free PMC article.
All time point measurements were taken from baseline. We classed outcomes as short-term when treatment duration was less than four weeks, and long-term when treatment was given for more than four weeks. ...
All time point measurements were taken from baseline. We classed outcomes as short-term when treatment duration was less than four we …
26 results