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Results from the 5-year SQ grass sublingual immunotherapy tablet asthma prevention (GAP) trial in children with grass pollen allergy.
Valovirta E, Petersen TH, Piotrowska T, Laursen MK, Andersen JS, Sørensen HF, Klink R; GAP investigators. Valovirta E, et al. J Allergy Clin Immunol. 2018 Feb;141(2):529-538.e13. doi: 10.1016/j.jaci.2017.06.014. Epub 2017 Jul 6. J Allergy Clin Immunol. 2018. PMID: 28689794 Free article. Clinical Trial.
CONCLUSIONS: Treatment with the SQ grass sublingual immunotherapy tablet reduced the risk of experiencing asthma symptoms and using asthma medication, and had a positive, long-term clinical effect on rhinoconjunctivitis symptoms and medication use but did not show an effec …
CONCLUSIONS: Treatment with the SQ grass sublingual immunotherapy tablet reduced the risk of experiencing asthma symptoms and using asthma m …
Effect of mattress and pillow encasings on children with asthma and house dust mite allergy.
Halken S, Høst A, Niklassen U, Hansen LG, Nielsen F, Pedersen S, Osterballe O, Veggerby C, Poulsen LK. Halken S, et al. Among authors: hansen lg. J Allergy Clin Immunol. 2003 Jan;111(1):169-76. doi: 10.1067/mai.2003.5. J Allergy Clin Immunol. 2003. PMID: 12532114 Clinical Trial.
OBJECTIVE: Our aim was to investigate whether mattress and pillow encasings resulted in an effective long-term control of HDM allergen levels, thereby reducing the need for asthma medication in children with asthma and HDM allergy. ...CONCLUSION: Encasing of mattresses and …
OBJECTIVE: Our aim was to investigate whether mattress and pillow encasings resulted in an effective long-term control of HDM allerge …
Changes in thyroid gland morphology after acute acrylamide exposure.
Khan MA, Davis CA, Foley GL, Friedman MA, Hansen LG. Khan MA, et al. Among authors: hansen lg. Toxicol Sci. 1999 Feb;47(2):151-7. doi: 10.1093/toxsci/47.2.151. Toxicol Sci. 1999. PMID: 10220851
Chronic lower exposure causes endocrine disruption associated with thyroid, testicular, and mammary tumors. To investigate mechanisms of endocrine disruption, short-term, low-level oral dosing studies were conducted. Weanling female Fischer 344 rats were acclimatized for t …
Chronic lower exposure causes endocrine disruption associated with thyroid, testicular, and mammary tumors. To investigate mechanisms of end …
Short-term distribution, metabolism, and excretion of 2,2',5-tri-, 2, 2',4,4'-tetra-, and 3,3',4,4'-tetrachlorobiphenyls in prepubertal rats.
Saghir SA, Koritz GD, Hansen LG. Saghir SA, et al. Among authors: hansen lg. Arch Environ Contam Toxicol. 1999 Feb;36(2):213-20. doi: 10.1007/s002449900463. Arch Environ Contam Toxicol. 1999. PMID: 9888968
This study suggests that prepubertal rats retain higher short-term serum levels and have lower excretion rates than adult rats....
This study suggests that prepubertal rats retain higher short-term serum levels and have lower excretion rates than adult rats....
Morphometric changes in the prepubertal female rat thyroid gland following acute exposure to 2,2',4,4'-tetrachlorobiphenyl and Aroclor 1242.
Saeed A, Hansen LG. Saeed A, et al. Among authors: hansen lg. J Toxicol Environ Health. 1997 Aug 8;51(5):503-13. doi: 10.1080/00984109708984040. J Toxicol Environ Health. 1997. PMID: 9233383
The rapid response of the thyroid gland to moderate decreases in serum T4 attenuates the observed decrease in T4 and may mask effects on T4 metabolism in short-term structure-activity studies. Morphometric measurements may be helpful in characterizing early and/or transien …
The rapid response of the thyroid gland to moderate decreases in serum T4 attenuates the observed decrease in T4 and may mask effects on T4 …
Responses of prepubertal female rats to environmental PCBs with high and low dioxin equivalencies.
Li MH, Hansen LG. Li MH, et al. Among authors: hansen lg. Fundam Appl Toxicol. 1996 Oct;33(2):282-93. doi: 10.1006/faat.1996.0166. Fundam Appl Toxicol. 1996. PMID: 8921347
Serum total T4 declined similarly in rats receiving either extract to about 40% of control values at the highest doses. Short-term integrated bioassays such as this are useful in detecting multiple complex interactions and can be used to define the net effects of mixtures …
Serum total T4 declined similarly in rats receiving either extract to about 40% of control values at the highest doses. Short-term in …
Toxicokinetic and Toxicodynamic Influences on Endocrine Disruption by Polychlorinated Biphenyls.
Soontornchat S, Li MH, Cooke PS, Hansen LG. Soontornchat S, et al. Among authors: hansen lg. Environ Health Perspect. 1994 Jun;102(6-7):568-71. doi: 10.1289/ehp.94102568. Environ Health Perspect. 1994. PMID: 9679117 Free PMC article.
It was not clear whether PROD activity was the cause of or a reflection of lower serum residues; however, nonplanar CBs are better substrates for PROD than are planar CBs, and the longer-term dosing may enhance metabolism and excretion, changing the biological effects obse …
It was not clear whether PROD activity was the cause of or a reflection of lower serum residues; however, nonplanar CBs are better substrate …
Effects of sewage sludge-fertilized corn fed to growing swine.
Hansen LG, Dorner JL, Byerly CS, Tarara RP, Hinesly TD. Hansen LG, et al. Am J Vet Res. 1976 Jun;37(6):711-4. Am J Vet Res. 1976. PMID: 937792
Corn heavily fertilized with sewage sludge from an urban-industrial complex can be safely fed to swine, based on these results, but it might be advantageous to feed on a short-term or intermittent schedule. Residues of heavy metals in the animal products must be examined.. …
Corn heavily fertilized with sewage sludge from an urban-industrial complex can be safely fed to swine, based on these results, but it might …