Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

4 results

Filters applied: . Clear all
Page 1
Changes in the R-region interactions depend on phosphorylation and contribute to PKA and PKC regulation of the cystic fibrosis transmembrane conductance regulator chloride channel.
Poroca DR, Amer N, Li A, Hanrahan JW, Chappe VM. Poroca DR, et al. Among authors: hanrahan jw. FASEB Bioadv. 2019 Dec 24;2(1):33-48. doi: 10.1096/fba.2019-00053. eCollection 2020 Jan. FASEB Bioadv. 2019. PMID: 32123855 Free PMC article.
The CFTR chloride channel is regulated by phosphorylation at PKA and PKC consensus sites within its regulatory region (R-region) through a mechanism, which is still not completely understood. We used a split-CFTR construct expressing the N-term-TMD1-NBD1 (Front Half; FH), …
The CFTR chloride channel is regulated by phosphorylation at PKA and PKC consensus sites within its regulatory region (R-region) through a m …
Altered channel properties of porins from Haemophilus influenzae: isolates from cystic fibrosis patients.
Arbing MA, Hanrahan JW, Coulton JW. Arbing MA, et al. Among authors: hanrahan jw. J Membr Biol. 2002 Sep 15;189(2):131-41. doi: 10.1007/s00232-002-1008-6. J Membr Biol. 2002. PMID: 12235488
Changes in amino-acid sequence of the unique pore-forming protein of H. influenzae (OmpP2; porin) have been associated with increased antimicrobial resistance in H. influenzae strains isolated from cystic fibrosis patients. From patients who were subjected to long-term ant …
Changes in amino-acid sequence of the unique pore-forming protein of H. influenzae (OmpP2; porin) have been associated with increased antimi …
Phosphorylation by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A.
Jia Y, Mathews CJ, Hanrahan JW. Jia Y, et al. Among authors: hanrahan jw. J Biol Chem. 1997 Feb 21;272(8):4978-84. doi: 10.1074/jbc.272.8.4978. J Biol Chem. 1997. PMID: 9030559 Free article.
PKC enhanced PKA stimulation of open probability without increasing the number of functional channels. Short-term pretreatment of cells with the PKC inhibitor chelerythrine (1 microM) reduced the channel activity that could be elicited by forskolin in cell-attached patches …
PKC enhanced PKA stimulation of open probability without increasing the number of functional channels. Short-term pretreatment of cel …
Plasma membrane Na+/H+ exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways.
Kandasamy RA, Yu FH, Harris R, Boucher A, Hanrahan JW, Orlowski J. Kandasamy RA, et al. Among authors: hanrahan jw. J Biol Chem. 1995 Dec 8;270(49):29209-16. doi: 10.1074/jbc.270.49.29209. J Biol Chem. 1995. PMID: 7493949 Free article.
Incubation of cells with either AIF4-, a general agonist of G proteins, or cholera toxin, a selective activator of G alpha s that stimulates adenylate cyclase, accelerated the rates of amiloride-inhibitable 22Na+ influx mediated by NHE-1 and -2, whereas they inhibited that by NHE …
Incubation of cells with either AIF4-, a general agonist of G proteins, or cholera toxin, a selective activator of G alpha s that stimulates …