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Predictors of imminent non-vertebral fracture in elderly women with osteoporosis, low bone mass, or a history of fracture, based on data from the population-based Canadian Multicentre Osteoporosis Study (CaMos).
Adachi JD, Berger C, Barron R, Weycker D, Anastassiades TP, Davison KS, Hanley DA, Ioannidis G, Jackson SA, Josse RG, Kaiser SM, Kovacs CS, Leslie WD, Morin SN, Papaioannou A, Prior JC, Shyta E, Silvia A, Towheed T, Goltzman D. Adachi JD, et al. Among authors: hanley da. Arch Osteoporos. 2019 May 16;14(1):53. doi: 10.1007/s11657-019-0598-x. Arch Osteoporos. 2019. PMID: 31098708
Careful consideration should be given to targeting this population for therapy. PURPOSE: Fracture risk assessment has focused on a long-term horizon and populations with a broad risk range. For elderly women with osteoporosis or low bone mass, or a history of fragility fra …
Careful consideration should be given to targeting this population for therapy. PURPOSE: Fracture risk assessment has focused on a long-t …
Incident Fragility Fractures Have a Long-Term Negative Impact on Health-Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study.
Borhan S, Papaioannou A, Gajic-Veljanoski O, Kennedy C, Ioannidis G, Berger C, Goltzman D, Josse R, Kovacs CS, Hanley DA, Prior JC, Morin SN, Kaiser SM, Cheung AM, Thabane L, Adachi J; CaMos Research Group. Borhan S, et al. Among authors: hanley da. J Bone Miner Res. 2019 May;34(5):838-848. doi: 10.1002/jbmr.3666. Epub 2019 Feb 5. J Bone Miner Res. 2019. PMID: 30723960 Free article. Clinical Trial.
Although the short-term impact of incident fragility fractures on health-related quality of life (HRQL) of older people has been confirmed, we lack long-term evidence. ...
Although the short-term impact of incident fragility fractures on health-related quality of life (HRQL) of older people has been conf …
Western Osteoporosis Alliance Clinical Practice Series: Evaluating the Balance of Benefits and Risks of Long-Term Osteoporosis Therapies.
Hanley DA, McClung MR, Davison KS, Dian L, Harris ST, Miller PD, Lewiecki EM, Kendler DL; Writing Group for the Western Osteoporosis Alliance. Hanley DA, et al. Am J Med. 2017 Jul;130(7):862.e1-862.e7. doi: 10.1016/j.amjmed.2017.03.002. Epub 2017 Mar 27. Am J Med. 2017. PMID: 28359721 Review.
Few trials have investigated the balance of benefits and risk with long-term use of osteoporosis therapies, and fewer still have investigated the consequences of treatment discontinuation. ...Other side effects associated with denosumab or bisphosphonates do not appear to …
Few trials have investigated the balance of benefits and risk with long-term use of osteoporosis therapies, and fewer still have inve …
Population-Wide Impact of Non-Hip Non-Vertebral Fractures on Mortality.
Tran T, Bliuc D, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse RG, Kaiser SM, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR. Tran T, et al. Among authors: hanley da. J Bone Miner Res. 2017 Sep;32(9):1802-1810. doi: 10.1002/jbmr.3118. Epub 2017 May 15. J Bone Miner Res. 2017. PMID: 28256011 Free article. Clinical Trial.
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two-thirds of all fragility fractures, are scanty. ...
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two-thirds of all fragility fr …
Improvement in Bone Mineral Density and Architecture in a Patient with Gaucher Disease Using Teriparatide.
Khan A, Hanley DA, McNeil C, Boyd S. Khan A, et al. Among authors: hanley da. JIMD Rep. 2015;22:23-8. doi: 10.1007/8904_2015_407. Epub 2015 Mar 3. JIMD Rep. 2015. PMID: 25732996 Free PMC article.
Our case involves a patient with complex disease affecting bone health including Gaucher disease (type I), Sjogren syndrome, rheumatoid arthritis and corticosteroid use who did not respond to long term use of bisphosphonates. We report an improvement in bone mineral densit …
Our case involves a patient with complex disease affecting bone health including Gaucher disease (type I), Sjogren syndrome, rheumatoid arth …
Clinical review: Effect of vitamin D3 supplementation on improving glucose homeostasis and preventing diabetes: a systematic review and meta-analysis.
Seida JC, Mitri J, Colmers IN, Majumdar SR, Davidson MB, Edwards AL, Hanley DA, Pittas AG, Tjosvold L, Johnson JA. Seida JC, et al. Among authors: hanley da. J Clin Endocrinol Metab. 2014 Oct;99(10):3551-60. doi: 10.1210/jc.2014-2136. Epub 2014 Jul 25. J Clin Endocrinol Metab. 2014. PMID: 25062463 Free PMC article. Review.
Definitive conclusions may be limited in the context of the moderate degree of heterogeneity, variable risk of bias, and short-term follow-up duration of the available evidence to date....
Definitive conclusions may be limited in the context of the moderate degree of heterogeneity, variable risk of bias, and short-term f …
Trends in hip fracture rates in Canada: an age-period-cohort analysis.
Jean S, O'Donnell S, Lagacé C, Walsh P, Bancej C, Brown JP, Morin S, Papaioannou A, Jaglal SB, Leslie WD; Osteoporosis Surveillance Expert Working Group. Jean S, et al. J Bone Miner Res. 2013 Jun;28(6):1283-9. doi: 10.1002/jbmr.1863. J Bone Miner Res. 2013. PMID: 23426882 Free PMC article. Clinical Trial.
After adjusting for age and constant annual linear change (drift term common to both period and cohort effects), we observed a significant nonlinear birth cohort effect for males (p = 0.0126) but not for females (p = 0.9960). ...For males, we observed no additional …
After adjusting for age and constant annual linear change (drift term common to both period and cohort effects), we observed a signif …
Oral bisphosphonates are associated with reduced mortality after hip fracture.
Beaupre LA, Morrish DW, Hanley DA, Maksymowych WP, Bell NR, Juby AG, Majumdar SR. Beaupre LA, et al. Among authors: hanley da. Osteoporos Int. 2011 Mar;22(3):983-91. doi: 10.1007/s00198-010-1411-2. Epub 2010 Nov 4. Osteoporos Int. 2011. PMID: 21052642
INTRODUCTION: Intravenous bisphosphonates reduce mortality following hip fracture. Using prospectively collected long-term data from a randomized trial of osteoporosis quality improvement for hip fracture, we determined whether new use of oral bisphosphonates was associate …
INTRODUCTION: Intravenous bisphosphonates reduce mortality following hip fracture. Using prospectively collected long-term data from …
Using the same bone density reference database for men and women provides a simpler estimation of fracture risk.
Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser S, Kreiger N; CaMOS Research Group. Langsetmo L, et al. Among authors: hanley da. J Bone Miner Res. 2010 Oct;25(10):2108-14. doi: 10.1002/jbmr.112. J Bone Miner Res. 2010. PMID: 20499356 Free PMC article.
In a model using sex-specific reference means but a common SD, an apparent sex difference emerged (HR = 0.66, 95% CI 0.54-0.81) for men versus women. The sex term in the second model counterbalanced the higher risk introduced by the lower normalized BMD in men. ...
In a model using sex-specific reference means but a common SD, an apparent sex difference emerged (HR = 0.66, 95% CI 0.54-0.81) for men vers …
Low 5-year stability of within-patient ion excretion and urine pH in fasting-morning-urine specimens.
Fenton TR, Eliasziw M, Lyon AW, Tough SC, Brown JP, Hanley DA. Fenton TR, et al. Among authors: hanley da. Nutr Res. 2009 May;29(5):320-6. doi: 10.1016/j.nutres.2009.04.005. Nutr Res. 2009. PMID: 19555813
This fair-to-moderate stability of fasting morning urine measures of the diet acid load indicates a limited ability of a single sample of fasting morning urine to estimate subjects' actual long-term urine composition....
This fair-to-moderate stability of fasting morning urine measures of the diet acid load indicates a limited ability of a single sample of fa …
23 results