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Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort.
McCready C, Zar HJ, Chaya S, Jacobs C, Workman L, Hantos Z, Hall GL, Sly PD, Nicol MP, Stein DJ, Ullah A, Custovic A, Little F, Gray DM. McCready C, et al. Among authors: hall gl. Lancet Child Adolesc Health. 2024 Jun;8(6):400-412. doi: 10.1016/S2352-4642(24)00072-5. Epub 2024 Apr 12. Lancet Child Adolesc Health. 2024. PMID: 38621408 Free article.
BACKGROUND: Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attained in adulthood and morbidity and mortality across the life course. We aimed to assess the effect of early-life lower respiratory tract infec …
BACKGROUND: Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attaine …
Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infants.
Urs R, Ni Chin R, Hemy N, Wilson AC, Pillow JJ, Hall GL, Simpson SJ. Urs R, et al. Among authors: hall gl. BMC Pediatr. 2023 Aug 5;23(1):386. doi: 10.1186/s12887-023-04210-y. BMC Pediatr. 2023. PMID: 37543578 Free PMC article.
METHODS: EBC samples and respiratory questionnaires were collected from 15 term-born infants and 33 preterm-born infants, 12 with a neonatal BPD diagnosis. ...RESULTS: Leukotriene B4 and 8-isoprostane levels were elevated in exhaled breath condensate of preterm-born infant …
METHODS: EBC samples and respiratory questionnaires were collected from 15 term-born infants and 33 preterm-born infants, 12 with a n …
Oscillometry and spirometry are not interchangeable when assessing the bronchodilator response in children and young adults born preterm.
Smith EF, Bradshaw TK, Urs RC, Evans DJ, Hemy NR, Hall GL, Wilson AC, Simpson SJ. Smith EF, et al. Among authors: hall gl. Pediatr Pulmonol. 2023 Nov;58(11):3122-3132. doi: 10.1002/ppul.26632. Epub 2023 Aug 4. Pediatr Pulmonol. 2023. PMID: 37539845 Free PMC article.
METHODS: Participants aged 6-23 born 32 (N = 288; 132 with bronchopulmonary dysplasia) and 37 weeks' gestation (N = 76, term-born controls) performed spirometry and oscillometry. A significant bronchodilator response (BDR) to 400 mug salbutamol was classified according to …
METHODS: Participants aged 6-23 born 32 (N = 288; 132 with bronchopulmonary dysplasia) and 37 weeks' gestation (N = 76, term-born con …
Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm.
Smith EF, Hemy NR, Hall GL, Wilson AC, Murray CP, Simpson SJ. Smith EF, et al. Among authors: hall gl. Thorax. 2023 Dec;78(12):1223-1232. doi: 10.1136/thorax-2022-219634. Epub 2023 May 19. Thorax. 2023. PMID: 37208189 Free article.
OBJECTIVES: To obtain comprehensive 'peak' lung health data from survivors of very preterm birth and identify neonatal and life-course risk factors for poorer respiratory outcomes in adulthood. ...A respiratory admission during childhood should, therefore, be considered a …
OBJECTIVES: To obtain comprehensive 'peak' lung health data from survivors of very preterm birth and identify neonatal and life-cours …
Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood.
Foong RE, Franklin P, Sanna F, Hall GL, Sly PD, Thorstensen EB, Doherty DA, Keelan JA, Hart RJ. Foong RE, et al. Among authors: hall gl. Respirology. 2023 Mar;28(3):236-246. doi: 10.1111/resp.14386. Epub 2022 Oct 2. Respirology. 2023. PMID: 36184579 Free PMC article.
BACKGROUND AND OBJECTIVE: Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies. However, little is known about the long-term effects of early life exposure to these compounds. W …
BACKGROUND AND OBJECTIVE: Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may incr …
Asthma and allergies in a cohort of adolescents conceived with ART.
Wijs LA, Doherty DA, Keelan JA, Penova-Veselinovic B, Burton P, Yovich JL, Hall GL, Sly PD, Holt PG, Hart RJ. Wijs LA, et al. Among authors: hall gl. Reprod Biomed Online. 2022 Dec;45(6):1255-1265. doi: 10.1016/j.rbmo.2022.07.007. Epub 2022 Jul 16. Reprod Biomed Online. 2022. PMID: 36182641
DESIGN: The Growing Up Healthy Study (GUHS) is a prospective cohort study including ART-conceived offspring born between 1991 and 2001 in Perth, Australia. Their long-term health outcomes, including asthma and allergy parameters, were compared with those of their counterpa …
DESIGN: The Growing Up Healthy Study (GUHS) is a prospective cohort study including ART-conceived offspring born between 1991 and 2001 in Pe …
Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study.
Sanna F, Locatelli F, Sly PD, White E, Blake D, Heyworth J, Hall GL, Foong RE. Sanna F, et al. Among authors: hall gl. ERJ Open Res. 2022 Mar 21;8(1):00072-2022. doi: 10.1183/23120541.00072-2022. eCollection 2022 Jan. ERJ Open Res. 2022. PMID: 35350282 Free PMC article.
The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. METHODS: Our study included participants from the Raine Study, a prospective pregnancy cohort, with at least two spirometry me …
The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung …
Pulmonary Gas Exchange Improves over the First Year in Preterm Infants with and without Bronchopulmonary Dysplasia.
Choi YJ, Stoecklin B, Hemy NR, Hall GL, Doherty DA, Simpson SJ, Pillow JJ. Choi YJ, et al. Among authors: hall gl. Neonatology. 2021;118(1):98-105. doi: 10.1159/000513357. Epub 2021 Feb 16. Neonatology. 2021. PMID: 33592606
Results were examined cross-sectionally at each time point, and longitudinally using generalized linear regression. Term infants were assessed at 44 wk PMA as a comparative reference. RESULTS: Longitudinal modelling showed continuous decline in shift in EP and VP infants d …
Results were examined cross-sectionally at each time point, and longitudinally using generalized linear regression. Term infants were …
Lung abnormalities do not influence aerobic capacity in school children born preterm.
O'Dea CA, Logie K, Wilson AC, Pillow JJ, Murray C, Banton G, Simpson SJ, Hall GL, Maiorana A. O'Dea CA, et al. Among authors: hall gl. Eur J Appl Physiol. 2021 Feb;121(2):489-498. doi: 10.1007/s00421-020-04530-2. Epub 2020 Nov 3. Eur J Appl Physiol. 2021. PMID: 33141263
RESULTS: Children born preterm with BPD had an elevated breathing frequency to tidal volume ratio compared to term controls (76% vs 63%, p = 0.002). The majority (88%) of preterm children had structural changes on CT scan. There were no differences in peak VO(2) (47.1 vs 4 …
RESULTS: Children born preterm with BPD had an elevated breathing frequency to tidal volume ratio compared to term controls (76% vs 6 …
30 results