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New insights into the metabolism of long chain polyunsaturated fatty acids during infancy.
Sauerwald TU, Hachey DL, Jensen CL, Heird WC. Sauerwald TU, et al. Among authors: hachey dl. Eur J Med Res. 1997 Feb 21;2(2):88-92. Eur J Med Res. 1997. PMID: 9085021 Review.
Data obtained with stable isotope methodology have demonstrated that preterm and term infants can convert LA and ALA, respectively, to AA and DHA. ...
Data obtained with stable isotope methodology have demonstrated that preterm and term infants can convert LA and ALA, respectively, t …
Intermediates in endogenous synthesis of C22:6 omega 3 and C20:4 omega 6 by term and preterm infants.
Sauerwald TU, Hachey DL, Jensen CL, Chen H, Anderson RE, Heird WC. Sauerwald TU, et al. Among authors: hachey dl. Pediatr Res. 1997 Feb;41(2):183-7. doi: 10.1203/00006450-199702000-00005. Pediatr Res. 1997. PMID: 9029636 Clinical Trial.
To determine whether this alternative pathway is operative in the human infant and also to obtain additional information concerning endogenous conversion of C18:3 omega 3 and C18:2 omega 6 to longer chain more unsaturated fatty acids, presence of [M + 18] isotopomers of omega 3 a …
To determine whether this alternative pathway is operative in the human infant and also to obtain additional information concerning endogeno …
Effect of dietary alpha-linolenic acid intake on incorporation of docosahexaenoic and arachidonic acids into plasma phospholipids of term infants.
Sauerwald TU, Hachey DL, Jensen CL, Chen H, Anderson RE, Heird WC. Sauerwald TU, et al. Among authors: hachey dl. Lipids. 1996 Mar;31 Suppl:S131-5. doi: 10.1007/BF02637064. Lipids. 1996. PMID: 8729107 Clinical Trial.
The fractional conversion rates of plasma phospholipid alpha-linolenic acid (18:3n-3) and linoleic acid (18:2n-6) to docosahexaenoic acid (22:6n-3) and arachidonic acid (20:4n-6), respectively, and the fractional rates of incorporation of 22:6n-3 and 20:4n-6 into plasma phospholi …
The fractional conversion rates of plasma phospholipid alpha-linolenic acid (18:3n-3) and linoleic acid (18:2n-6) to docosahexaenoic acid (2 …
Effects of infant nutrition on cholesterol synthesis rates.
Cruz ML, Wong WW, Mimouni F, Hachey DL, Setchell KD, Klein PD, Tsang RC. Cruz ML, et al. Among authors: hachey dl. Pediatr Res. 1994 Feb;35(2):135-40. doi: 10.1203/00006450-199402000-00001. Pediatr Res. 1994. PMID: 8165045 Clinical Trial.
We hypothesized that FSR is significantly reduced with high dietary cholesterol and phytoestrogen intake and increased with low dietary cholesterol and phytoestrogen intake. We prospectively studied 33 term male infants exclusively fed human milk (high cholesterol, low phy …
We hypothesized that FSR is significantly reduced with high dietary cholesterol and phytoestrogen intake and increased with low dietary chol …
Manipulation of maternal diet to alter fatty acid composition of human milk intended for premature infants.
Silber GH, Hachey DL, Schanler RJ, Garza C. Silber GH, et al. Among authors: hachey dl. Am J Clin Nutr. 1988 May;47(5):810-4. doi: 10.1093/ajcn/47.5.810. Am J Clin Nutr. 1988. PMID: 3364395
Ten lactating mothers (five of preterm and five of term infants) 9-17 d postpartum consumed a 5% fat, 15% protein, and 80% carbohydrate diet for 5 d. ...Significant increases in the sum of the absolute and relative concentrations of C10:0, C12:0, and C14:0 fatty acids and …
Ten lactating mothers (five of preterm and five of term infants) 9-17 d postpartum consumed a 5% fat, 15% protein, and 80% carbohydra …
Quantitation of methadone enantiomers in humans using stable isotope-labeled [2H3]-, [2H5]-, and [2H8]Methadone.
Nakamura K, Hachey DL, Kreek MJ, Irving CS, Klein PD. Nakamura K, et al. Among authors: hachey dl. J Pharm Sci. 1982 Jan;71(1):40-3. doi: 10.1002/jps.2600710110. J Pharm Sci. 1982. PMID: 7057377
A racemic mixture (1:1) of (R)-(-)-[2H5]methadone (l-form) and (S)-(R)-[2H3]methadone (d-form) was administered orally in place of a single daily dose of unlabeled (+/-)-[2H0]methadone in long-term maintenance patients. Racemic (+/-)-[2H8]methadone was used as an internal …
A racemic mixture (1:1) of (R)-(-)-[2H5]methadone (l-form) and (S)-(R)-[2H3]methadone (d-form) was administered orally in place of a single …