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A pathway of targeted autophagy is induced by DNA damage in budding yeast.
Eapen VV, Waterman DP, Bernard A, Schiffmann N, Sayas E, Kamber R, Lemos B, Memisoglu G, Ang J, Mazella A, Chuartzman SG, Loewith RJ, Schuldiner M, Denic V, Klionsky DJ, Haber JE. Eapen VV, et al. Among authors: haber je. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1158-E1167. doi: 10.1073/pnas.1614364114. Epub 2017 Feb 2. Proc Natl Acad Sci U S A. 2017. PMID: 28154131 Free PMC article.
Using budding yeast, we demonstrate that global genotoxic damage or even a single unrepaired double-strand break (DSB) initiates a previously undescribed and selective pathway of autophagy that we term genotoxin-induced targeted autophagy (GTA). GTA requires the action pri …
Using budding yeast, we demonstrate that global genotoxic damage or even a single unrepaired double-strand break (DSB) initiates a previousl …
Messenger ribonucleic acid and protein metabolism during sporulation of Saccharomyces cerevisiae.
Kraig E, Haber JE. Kraig E, et al. Among authors: haber je. J Bacteriol. 1980 Dec;144(3):1098-1112. doi: 10.1128/jb.144.3.1098-1112.1980. J Bacteriol. 1980. PMID: 7002906 Free PMC article.
We compared proteins labeled by various protocols, including long-term and pulse-labeling during sporulation and prelabeling during vegetative growth before transfer to sporulation medium. The resulting two-dimensional gel patterns differed significantly. Many spots labele …
We compared proteins labeled by various protocols, including long-term and pulse-labeling during sporulation and prelabeling during v …