Gene expression and epigenetic aberrations in F1-placentas fathered by obese males.
Mitchell M, Strick R, Strissel PL, Dittrich R, McPherson NO, Lane M, Pliushch G, Potabattula R, Haaf T, El Hajj N.
Mitchell M, et al. Among authors: haaf t.
Mol Reprod Dev. 2017 Apr;84(4):316-328. doi: 10.1002/mrd.22784. Epub 2017 Mar 3.
Mol Reprod Dev. 2017.
PMID: 28186371
We therefore propose that paternal obesity renders changes in gene expression and/or methylation throughout the placental genome, which could contribute to the reproductive problems related to fertility and to the metabolic, long-term health impact on offspring....
We therefore propose that paternal obesity renders changes in gene expression and/or methylation throughout the placental genome, which coul …