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Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice.
Florian C, Vecsey CG, Halassa MM, Haydon PG, Abel T. Florian C, et al. J Neurosci. 2011 May 11;31(19):6956-62. doi: 10.1523/JNEUROSCI.5761-10.2011. J Neurosci. 2011. PMID: 21562257 Free PMC article.
In this study, we examined whether genetic disruption of soluble N-ethylmaleimide-sensitive factor attached protein (SNARE)-dependent exocytosis in astrocytes (dnSNARE mice) or pharmacological blockade of A1 receptor signaling using an adenosine A1 receptor (A1R) antagonist, 8-cy …
In this study, we examined whether genetic disruption of soluble N-ethylmaleimide-sensitive factor attached protein (SNARE)-dependent exocyt …
Sleep deprivation impairs cAMP signalling in the hippocampus.
Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T. Vecsey CG, et al. Nature. 2009 Oct 22;461(7267):1122-5. doi: 10.1038/nature08488. Nature. 2009. PMID: 19847264 Free PMC article.