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Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis.
Roedl K, Wallmüller C, Drolz A, Horvatits T, Rutter K, Spiel A, Ortbauer J, Stratil P, Hubner P, Weiser C, Motaabbed JK, Jarczak D, Herkner H, Sterz F, Fuhrmann V. Roedl K, et al. Among authors: hubner p. Ann Intensive Care. 2017 Oct 6;7(1):103. doi: 10.1186/s13613-017-0322-1. Ann Intensive Care. 2017. PMID: 28986855 Free PMC article.
Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis. ...
Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as fun …
Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials.
Packer M, McMurray JJV, Krum H, Kiowski W, Massie BM, Caspi A, Pratt CM, Petrie MC, DeMets D, Kobrin I, Roux S, Swedberg K; ENABLE Investigators and Committees. Packer M, et al. JACC Heart Fail. 2017 May;5(5):317-326. doi: 10.1016/j.jchf.2017.02.021. JACC Heart Fail. 2017. PMID: 28449795 Free article. Review.
OBJECTIVES: The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure. BACKGROUND: Endothelin may play a role in heart failure, but …
OBJECTIVES: The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan …
The mammalian efferent vestibular system plays a crucial role in vestibulo-ocular reflex compensation after unilateral labyrinthectomy.
Hübner PP, Khan SI, Migliaccio AA. Hübner PP, et al. J Neurophysiol. 2017 Apr 1;117(4):1553-1568. doi: 10.1152/jn.01049.2015. Epub 2017 Jan 11. J Neurophysiol. 2017. PMID: 28077670 Free PMC article.
A recent study has shown that alpha9-nAChRs play an important role in short-term vestibulo-ocular reflex (VOR) adaptation. We hypothesize that alpha9-nAChRs could also be important for other forms of vestibular plasticity, such as that needed for VOR recovery after vestibu …
A recent study has shown that alpha9-nAChRs play an important role in short-term vestibulo-ocular reflex (VOR) adaptation. We hypothe …
Aging reduces the high-frequency and short-term adaptation of the vestibulo-ocular reflex in mice.
Khan SI, Hübner PP, Brichta AM, Smith DW, Migliaccio AA. Khan SI, et al. Among authors: hubner pp. Neurobiol Aging. 2017 Mar;51:122-131. doi: 10.1016/j.neurobiolaging.2016.12.007. Epub 2016 Dec 18. Neurobiol Aging. 2017. PMID: 28063365
Although mice are commonly used in mechanistic studies of vestibular function, it remains unclear whether aging produces a corresponding decline in VOR function in mice. We sought to determine how the baseline VOR and its short-term adaptation were affected by aging. We te …
Although mice are commonly used in mechanistic studies of vestibular function, it remains unclear whether aging produces a corresponding dec …
The mammalian efferent vestibular system plays a crucial role in the high-frequency response and short-term adaptation of the vestibuloocular reflex.
Hübner PP, Khan SI, Migliaccio AA. Hübner PP, et al. J Neurophysiol. 2015 Dec;114(6):3154-65. doi: 10.1152/jn.00307.2015. Epub 2015 Sep 30. J Neurophysiol. 2015. PMID: 26424577 Free PMC article.
Unlike in fish and reptiles, the mammalian EVS does not seem to play a role in modulation of primary afferent activity in anticipation of active head movements. However, it could play a role in modulating long-term mechanisms requiring plasticity such as vestibular adaptat …
Unlike in fish and reptiles, the mammalian EVS does not seem to play a role in modulation of primary afferent activity in anticipation of ac …
[DGRW-Update: Rehabilitation in Diabetes Mellitus].
Pollmann H, Hübner P. Pollmann H, et al. Among authors: hubner p. Rehabilitation (Stuttg). 2013 Aug;52(4):234-42. doi: 10.1055/s-0033-1343487. Epub 2013 Aug 28. Rehabilitation (Stuttg). 2013. PMID: 23986288 German.
Sustainability of rehabilitative effects must be improved by means of follow-up treatment and networking with the ambulant structures of long-term care. Provided that the indication makes it appropriate, bariatric surgery constitutes a new effective therapy....
Sustainability of rehabilitative effects must be improved by means of follow-up treatment and networking with the ambulant structures of lon …
[Fractionated inpatient rehabilitation of diabetes: results from a randomized controlled trial on rehabilitation aftercare].
Ernst G, Hübner P. Ernst G, et al. Among authors: hubner p. Rehabilitation (Stuttg). 2012 Oct;51(5):308-15. doi: 10.1055/s-0031-1291282. Epub 2012 Apr 4. Rehabilitation (Stuttg). 2012. PMID: 22477640 Clinical Trial. German.
BACKGROUND: Treating diabetes mellitus type 2 (DMT2) essentially involves long-term changes of health behaviour, especially diet and physical activity habits. ...However, positive long-term changes of physiological parameters probably will require more specific inte …
BACKGROUND: Treating diabetes mellitus type 2 (DMT2) essentially involves long-term changes of health behaviour, especially diet and …
European hospitals as a source for platinum in the environment in comparison with other sources.
Kümmerer K, Helmers E, Hubner P, Mascart G, Milandri M, Reinthaler F, Zwakenberg M. Kümmerer K, et al. Among authors: hubner p. Sci Total Environ. 1999 Jan 12;225(1-2):155-65. doi: 10.1016/s0048-9697(98)00341-6. Sci Total Environ. 1999. PMID: 10028712
The concentration of platinum in the sewage of five European hospitals originating from excreted antineoplastic drugs, cisplatin and carboplatin, was analyzed in a short term study to provide an order of magnitude of Pt emissions from hospitals into aquatic environments. . …
The concentration of platinum in the sewage of five European hospitals originating from excreted antineoplastic drugs, cisplatin and carbopl …
The Subcutaneous Heparin and Angioplasty Restenosis Prevention (SHARP) trial. Results of a multicenter randomized trial investigating the effects of high dose unfractionated heparin on angiographic restenosis and clinical outcome.
Brack MJ, Ray S, Chauhan A, Fox J, Hubner PJ, Schofield P, Harley A, Gershlick AH. Brack MJ, et al. Among authors: hubner pj. J Am Coll Cardiol. 1995 Oct;26(4):947-54. doi: 10.1016/0735-1097(95)00277-4. J Am Coll Cardiol. 1995. PMID: 7560622 Free article. Clinical Trial.
Clinical events during the follow-up period did not differ significantly between groups: fatal myocardial infarction (1 patient in each group), coronary bypass grafting (5 patients in each group), repeat angioplasty (12 in the no heparin, 6 in the heparin group), angina at 4-mont …
Clinical events during the follow-up period did not differ significantly between groups: fatal myocardial infarction (1 patient in each grou …
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