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Detrimental effects of 6 months exposure to very low doses of a mixture of six pesticides associated with chronic vitamin deficiency on rats.
Tsatsakis A, Tyshko NV, Goumenou M, Shestakova SI, Sadykova EO, Zhminchenko VM, Zlatian O, Calina D, Pashorina VA, Nikitin NS, Trebukh MD, Loginova MS, Trushina EN, Mustafina OK, Avrenyeva LI, Guseva GV, Trusov NV, Kravchenko LV, Hernández AF, Docea AO. Tsatsakis A, et al. Among authors: guseva gv. Food Chem Toxicol. 2021 Jun;152:112188. doi: 10.1016/j.fct.2021.112188. Epub 2021 Apr 6. Food Chem Toxicol. 2021. PMID: 33836210
This study aimed to evaluate the long-term low-dose effects of exposure to a mixture of 6 pesticide active substances (diquat, imazamox, imazethapyr, tepraloxydin, bentazone, acifluorfen) and to elucidate if chronic vitamin deficiency can influence their toxicity. ...
This study aimed to evaluate the long-term low-dose effects of exposure to a mixture of 6 pesticide active substances (diquat, imazam …
Activity of xenobiotic-metabolizing enzymes in the liver of rats with multi-vitamin deficiency.
Tutelyan VA, Kravchenko LV, Aksenov IV, Trusov NV, Guseva GV, Kodentsova VM, Vrzhesinskaya OA, Beketova NA. Tutelyan VA, et al. Among authors: guseva gv. Int J Vitam Nutr Res. 2013;83(1):5-13. doi: 10.1024/0300-9831/a000140. Int J Vitam Nutr Res. 2013. PMID: 24220160
The study has demonstrated that profound multi-vitamin deficiency is associated with a decrease in the expression of CYP1A2 and CYP3A1 mRNAs to 62 % and 79 %, respectively. These data indicated that a short-term but profound multi-vitamin deficiency in rats leads to a decr …
The study has demonstrated that profound multi-vitamin deficiency is associated with a decrease in the expression of CYP1A2 and CYP3A1 mRNAs …