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Exploration of Sleep as a Specific Risk Factor for Poor Metabolic and Mental Health: A UK Biobank Study of 84,404 Participants.
Zhu G, Cassidy S, Hiden H, Woodman S, Trenell M, Gunn DA, Catt M, Birch-Machin M, Anderson KN. Zhu G, et al. Among authors: gunn da. Nat Sci Sleep. 2021 Oct 22;13:1903-1912. doi: 10.2147/NSS.S323160. eCollection 2021. Nat Sci Sleep. 2021. PMID: 34712066 Free PMC article.
CONCLUSION: Six to eight hours of sleep, as well as less fragmented sleep, predicted better long-term metabolic and mental health....
CONCLUSION: Six to eight hours of sleep, as well as less fragmented sleep, predicted better long-term metabolic and mental health....
To treat or not to treat: perceptions of the initial American Society for Reproductive Medicine COVID-19 recommendations among women's health providers.
Wiltshire A, Jackson-Bey T, Walker Z, Chiang JL, MacLennan PA, Gunn D, Hurd WW. Wiltshire A, et al. Among authors: gunn d. J Assist Reprod Genet. 2021 Mar;38(3):621-626. doi: 10.1007/s10815-021-02064-w. Epub 2021 Jan 14. J Assist Reprod Genet. 2021. PMID: 33447949 Free PMC article.
Participants within the subspecialties of general Ob/Gyn, maternal foetal medicine and gynecologic oncology were significantly more likely to disagree that all women should refrain from planned conception during the COVID-19 pandemic, in comparison to those in urogynecology and r …
Participants within the subspecialties of general Ob/Gyn, maternal foetal medicine and gynecologic oncology were significantly more likely t …
High-risk Corneal Transplantation: Recent Developments and Future Possibilities.
Armitage WJ, Goodchild C, Griffin MD, Gunn DJ, Hjortdal J, Lohan P, Murphy CC, Pleyer U, Ritter T, Tole DM, Vabres B. Armitage WJ, et al. Among authors: gunn dj. Transplantation. 2019 Dec;103(12):2468-2478. doi: 10.1097/TP.0000000000002938. Transplantation. 2019. PMID: 31765363 Free PMC article. Review.
Human corneal transplantation (keratoplasty) is typically considered to have superior short- and long-term outcomes and lower requirement for immunosuppression compared to solid organ transplants because of the inherent immune privilege and tolerogenic mechanisms associate …
Human corneal transplantation (keratoplasty) is typically considered to have superior short- and long-term outcomes and lower require …
Risk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial.
McGarry A, McDermott MP, Kieburtz K, Fung WLA, McCusker E, Peng J, de Blieck EA, Cudkowicz M; Huntington Study Group 2CARE Investigators and Coordinators. McGarry A, et al. Neurology. 2019 Apr 2;92(14):e1643-e1651. doi: 10.1212/WNL.0000000000007244. Epub 2019 Mar 8. Neurology. 2019. PMID: 30850442 Free PMC article.
Designing a composite algorithm for early prediction of suicide attempts in HD may be of value, particularly given anticipated trials aimed at disease modification are likely to be long-term. CLINICALTRIALSGOV IDENTIFIER: NCT00608881....
Designing a composite algorithm for early prediction of suicide attempts in HD may be of value, particularly given anticipated trials aimed …
Do senescence markers correlate in vitro and in situ within individual human donors?
Waaijer MEC, Gunn DA, van Heemst D, Slagboom PE, Sedivy JM, Dirks RW, Tanke HJ, Westendorp RGJ, Maier AB. Waaijer MEC, et al. Among authors: gunn da. Aging (Albany NY). 2018 Feb 28;10(2):278-289. doi: 10.18632/aging.101389. Aging (Albany NY). 2018. PMID: 29500330 Free PMC article.
Furthermore, we tested correlations between in vitro markers with in situ p16INK4a positivity.From 100 donors (20-91 years), cultured dermal fibroblasts were assessed for reactive oxygen species (ROS), telomere-associated foci (TAF), p16INK4a and senescence-associated beta-gal (S …
Furthermore, we tested correlations between in vitro markers with in situ p16INK4a positivity.From 100 donors (20-91 years), cultured dermal …
Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.
Mehta RH, Leimberger JD, van Diepen S, Meza J, Wang A, Jankowich R, Harrison RW, Hay D, Fremes S, Duncan A, Soltesz EG, Luber J, Park S, Argenziano M, Murphy E, Marcel R, Kalavrouziotis D, Nagpal D, Bozinovski J, Toller W, Heringlake M, Goodman SG, Levy JH, Harrington RA, Anstrom KJ, Alexander JH; LEVO-CTS Investigators. Mehta RH, et al. N Engl J Med. 2017 May 25;376(21):2032-2042. doi: 10.1056/NEJMoa1616218. Epub 2017 Mar 19. N Engl J Med. 2017. PMID: 28316276 Free article. Clinical Trial.
CONCLUSIONS: Prophylactic levosimendan did not result in a rate of the short-term composite end point of death, renal-replacement therapy, perioperative myocardial infarction, or use of a mechanical cardiac assist device that was lower than the rate with placebo among pati …
CONCLUSIONS: Prophylactic levosimendan did not result in a rate of the short-term composite end point of death, renal-replacement the …
Lifestyle and youthful looks.
Gunn DA, Dick JL, van Heemst D, Griffiths CE, Tomlin CC, Murray PG, Griffiths TW, Ogden S, Mayes AE, Westendorp RG, Slagboom PE, de Craen AJ. Gunn DA, et al. Br J Dermatol. 2015;172(5):1338-45. doi: 10.1111/bjd.13646. Epub 2015 Apr 15. Br J Dermatol. 2015. PMID: 25627783
CONCLUSIONS: Although associative in nature, these results support the notion that lifestyle factors can have long-term beneficial effects on youthful looks....
CONCLUSIONS: Although associative in nature, these results support the notion that lifestyle factors can have long-term beneficial ef …
Glycaemic control and weight 7 years after Dose Adjustment For Normal Eating (DAFNE) structured education in Type 1 diabetes.
Gunn D, Mansell P. Gunn D, et al. Diabet Med. 2012 Jun;29(6):807-12. doi: 10.1111/j.1464-5491.2011.03525.x. Diabet Med. 2012. PMID: 22132868
AIMS: The provision of structured education is increasingly prevalent in the management of Type 1 diabetes. There are little long-term follow-up data from such programmes. We have assessed HbA(1c) and weight over a 7-year period following the Dose Adjustment For Normal Eat …
AIMS: The provision of structured education is increasingly prevalent in the management of Type 1 diabetes. There are little long-term …
High serum glucose levels are associated with a higher perceived age.
Noordam R, Gunn DA, Tomlin CC, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ, van Heemst D; Leiden Longevity Study Group. Noordam R, et al. Among authors: gunn da. Age (Dordr). 2013 Feb;35(1):189-95. doi: 10.1007/s11357-011-9339-9. Epub 2011 Nov 20. Age (Dordr). 2013. PMID: 22102339 Free PMC article.
Non-diabetic subjects (n = 569) were divided in three strata according to their glucose levels, and diabetic subjects (n = 33; as a proxy of long-term hyperglycemic exposure) were included as a fourth stratum. Considered confounding factors were gender, chronological age, …
Non-diabetic subjects (n = 569) were divided in three strata according to their glucose levels, and diabetic subjects (n = 33; as a proxy of …
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