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A highly virulent variant of HIV-1 circulating in the Netherlands.
Wymant C, Bezemer D, Blanquart F, Ferretti L, Gall A, Hall M, Golubchik T, Bakker M, Ong SH, Zhao L, Bonsall D, de Cesare M, MacIntyre-Cockett G, Abeler-Dörner L, Albert J, Bannert N, Fellay J, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Laeyendecker O, Meyer L, Porter K, Ristola M, van Sighem A, Berkhout B, Kellam P, Cornelissen M, Reiss P, Fraser C; Netherlands ATHENA HIV Observational Cohort†; BEEHIVE Collaboration†. Wymant C, et al. Science. 2022 Feb 4;375(6580):540-545. doi: 10.1126/science.abk1688. Epub 2022 Feb 3. Science. 2022. PMID: 35113714 Free article.
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expected to be reached, on average, 9 months after diagnosis for individuals in their thirties with this variant. Age, sex, suspected mode of trans …
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expecte …
Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.
Molinos-Albert LM, Lorin V, Monceaux V, Orr S, Essat A, Dufloo J, Schwartz O, Rouzioux C, Meyer L, Hocqueloux L, Sáez-Cirión A, Mouquet H; ANRS VISCONTI Study Group. Molinos-Albert LM, et al. Nat Commun. 2022 Apr 11;13(1):1944. doi: 10.1038/s41467-022-29511-1. Nat Commun. 2022. PMID: 35410989 Free PMC article.
Here, we perform comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers. Global multivariate analyses combining clinico-virological and humoral immune data reveal distinct profiles in post-treatment controllers experiencing t …
Here, we perform comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers. Global multi …
Doravirine plus lamivudine two-drug regimen as maintenance antiretroviral therapy in people living with HIV: a French observational study.
Perfezou P, Hall N, Duthe JC, Abdi B, Seang S, Arvieux C, Lamaury I, Menard A, Marcelin AG, Katlama C, Palich R; Dat’AIDS study group. Perfezou P, et al. J Antimicrob Chemother. 2023 Aug 2;78(8):1929-1933. doi: 10.1093/jac/dkad185. J Antimicrob Chemother. 2023. PMID: 37303236 Free article.
CONCLUSIONS: These preliminary findings suggest that doravirine/lamivudine regimens can maintain high levels of viral suppression in highly ART-experienced PLWH with long-term viral suppression, and good CD4+ T cell count....
CONCLUSIONS: These preliminary findings suggest that doravirine/lamivudine regimens can maintain high levels of viral suppression in highly …
Case Studies and Literature Review of Francisella tularensis-Related Prosthetic Joint Infection.
Ponderand L, Guimard T, Lazaro E, Dupuy H, Peuchant O, Roch N, Deroche P, Ferry T, Maurin M, Hennebique A, Boisset S, Pelloux I, Caspar Y. Ponderand L, et al. Among authors: guimard t. Emerg Infect Dis. 2023 Jun;29(6):1118-1126. doi: 10.3201/eid2906.221395. Emerg Infect Dis. 2023. PMID: 37209668 Free PMC article. Review.
F. tularensis was initially identified in 2 patients by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; molecular methods were used for 6 patients. Surgical treatment in conjunction with long-term antimicrobial treatment resulted in favorable …
F. tularensis was initially identified in 2 patients by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; molecu …
Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study.
Battaglini D, White NM, Premraj L, Wanjiru Citarella B, Merson L, Robba C, Thomson D, Cho SM; ISARIC Clinical Characterization Group. Battaglini D, et al. J Neurol. 2024 Jan;271(1):79-86. doi: 10.1007/s00415-023-12133-y. Epub 2023 Dec 6. J Neurol. 2024. PMID: 38055020 Free PMC article. No abstract available.
Persistent headaches one year after bacterial meningitis: prevalence, determinants and impact on quality of life.
Van RN, Tubiana S, De Broucker T, Cédric J, Roy C, Meyohas MC, Prazuck T, Chirouze C, Hoen B, Duval X, Revest M; COMBAT study group. Van RN, et al. Eur J Clin Microbiol Infect Dis. 2023 Dec;42(12):1459-1467. doi: 10.1007/s10096-023-04673-y. Epub 2023 Oct 23. Eur J Clin Microbiol Infect Dis. 2023. PMID: 37867184
BACKGROUND: Little is known on headaches long-term persistence after bacterial meningitis and on their impact on patients' quality of life. ...
BACKGROUND: Little is known on headaches long-term persistence after bacterial meningitis and on their impact on patients' quality of …
One-Year Sequelae and Quality of Life in Adults with Meningococcal Meningitis: Lessons from the COMBAT Multicentre Prospective Study.
Duval X, Taha MK, Lamaury I, Escaut L, Gueit I, Manchon P, Tubiana S, Hoen B; COMBAT study group. Duval X, et al. Adv Ther. 2022 Jun;39(6):3031-3041. doi: 10.1007/s12325-022-02149-7. Epub 2022 Apr 28. Adv Ther. 2022. PMID: 35484469 Free PMC article.
CONCLUSIONS: Although most patients in our cohort survive meningococcal meningitis, the long-term burden is substantial and therefore it is important to ensure a prolonged follow-up of survivors and to promote preventive strategies, including vaccination. ...
CONCLUSIONS: Although most patients in our cohort survive meningococcal meningitis, the long-term burden is substantial and therefore …
Community-acquired bacterial meningitis in adults: in-hospital prognosis, long-term disability and determinants of outcome in a multicentre prospective cohort.
Tubiana S, Varon E, Biron C, Ploy MC, Mourvillier B, Taha MK, Revest M, Poyart C, Martin-Blondel G, Lecuit M, Cua E, Pasquet B, Preau M, Hoen B, Duval X; COMBAT study group. Tubiana S, et al. Clin Microbiol Infect. 2020 Sep;26(9):1192-1200. doi: 10.1016/j.cmi.2019.12.020. Epub 2020 Jan 10. Clin Microbiol Infect. 2020. PMID: 31927117 Free article.
Factors associated with unfavourable outcome were identified by logistic regression and long-term disability was analysed. RESULTS: Among the 533 individuals enrolled, (Streptococcus pneumoniae 53.8% (280/520 isolates identified), Neisseria meningitidis 21.3% (111/520), ot …
Factors associated with unfavourable outcome were identified by logistic regression and long-term disability was analysed. RESULTS: A …
15 results