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Rituximab as maintenance therapy for ANCA-associated vasculitides: pooled analysis and long-term outcome of 277 patients included in the MAINRITSAN trials.
Delestre F, Charles P, Karras A, Pagnoux C, Néel A, Cohen P, Aumaître O, Faguer S, Gobert P, Maurier F, Samson M, Godmer P, Bonnotte B, Cottin V, Hanrotel-Saliou C, Le Gallou T, Carron PL, Desmurs-Clavel H, Direz G, Jourde-Chiche N, Lifermann F, Martin-Silva N, Pugnet G, Quéméneur T, Matignon M, Benhamou Y, Daugas E, Lazaro E, Limal N, Ducret M, Huart A, Viallard JF, Hachulla E, Perrodeau E, Puechal X, Guillevin L, Porcher R, Terrier B; French Vasculitis Study Group (FVSG). Delestre F, et al. Among authors: guillevin l. Ann Rheum Dis. 2024 Jan 11;83(2):233-241. doi: 10.1136/ard-2023-224623. Ann Rheum Dis. 2024. PMID: 37918894
OBJECTIVE: To compare the long-term efficacy and safety of azathioprine (AZA), 18-month fixed-schedule rituximab (RTX), 18-month tailored RTX and 36-month RTX in preventing relapses in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who achie …
OBJECTIVE: To compare the long-term efficacy and safety of azathioprine (AZA), 18-month fixed-schedule rituximab (RTX), 18-month tail …
Clinical features and long-term outcomes of patients with systemic polyarteritis nodosa diagnosed since 2005: Data from 196 patients.
Rohmer J, Nguyen Y, Trefond L, Agard C, Allain JS, Berezne A, Charles P, Cohen P, Gondran G, Groh M, Huscenot T, Lacout C, Lazaro E, London J, Maurier F, Mekinian A, Mesbah R, Nubourgh I, Perard L, Puéchal X, Pugnet G, Puyade M, Queyrel V, Roux A, Rouzaud D, Durel CA, Guillevin L, Terrier B; French Vasculitis Study Group (FVSG). Rohmer J, et al. Among authors: guillevin l. J Autoimmun. 2023 Sep;139:103093. doi: 10.1016/j.jaut.2023.103093. Epub 2023 Aug 1. J Autoimmun. 2023. PMID: 37536165
Prognostic value of automated assessment of interstitial lung disease on CT in systemic sclerosis.
Le Gall A, Hoang-Thi TN, Porcher R, Dunogué B, Berezné A, Guillevin L, Le Guern V, Cohen P, Chaigne B, London J, Groh M, Paule R, Chassagnon G, Vakalopoulou M, Dinh-Xuan AT, Revel MP, Mouthon L, Régent A. Le Gall A, et al. Among authors: guillevin l. Rheumatology (Oxford). 2024 Jan 4;63(1):103-110. doi: 10.1093/rheumatology/kead164. Rheumatology (Oxford). 2024. PMID: 37074923
CONCLUSION: The deep-learning-based, computer-aided quantification of ILD extent on HRCT provides an effective tool for risk stratification in SSc. It might help identify patients at short-term risk of death....
CONCLUSION: The deep-learning-based, computer-aided quantification of ILD extent on HRCT provides an effective tool for risk stratification …
Score to assess the probability of relapse in granulomatosis with polyangiitis and microscopic polyangiitis.
Samson M, Devilliers H, Thietart S, Charles P, Pagnoux C, Cohen P, Karras A, Mouthon L, Terrier B, Puéchal X, Guillevin L. Samson M, et al. Among authors: guillevin l. RMD Open. 2023 Mar;9(1):e002953. doi: 10.1136/rmdopen-2022-002953. RMD Open. 2023. PMID: 36972927 Free PMC article.
OBJECTIVE: To develop a score assessing the probability of relapse in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). METHODS: Long-term follow-up data from GPA and MPA patients included in five consecutive randomised controlled trials were poole …
OBJECTIVE: To develop a score assessing the probability of relapse in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (M …
Proteinuria and hematuria after remission induction are associated with outcome in ANCA-associated vasculitis.
Benichou N, Charles P, Terrier B, Jones RB, Hiemstra T, Mouthon L, Bajema I, Berden A, Thervet E, Guillevin L, Jayne D, Karras A; French Vasculitis Study Group (FVSG) and European Vasculitis Society (EUVAS) investigators. Benichou N, et al. Among authors: guillevin l. Kidney Int. 2023 Jun;103(6):1144-1155. doi: 10.1016/j.kint.2023.02.029. Epub 2023 Mar 20. Kidney Int. 2023. PMID: 36940799 Clinical Trial.
Thus, in this large cohort of patients with AAV, persistent proteinuria after induction therapy was associated with death/kidney failure and kidney relapse, whereas persistent hematuria was an independent predictor of kidney relapse. Hence, these parameters must be considered to …
Thus, in this large cohort of patients with AAV, persistent proteinuria after induction therapy was associated with death/kidney failure and …
Remission and Low Disease Activity in Granulomatosis With Polyangiitis and Microscopic Polyangiitis: Prevalence and Impact on Damage Accrual.
Delvino P, Sardanelli F, Monti S, Cohen P, Puéchal X, Mouthon L, Montecucco C, Guillevin L, Terrier B. Delvino P, et al. Among authors: guillevin l. Arthritis Care Res (Hoboken). 2023 May;75(5):1158-1165. doi: 10.1002/acr.24958. Epub 2022 Dec 21. Arthritis Care Res (Hoboken). 2023. PMID: 35604889 Free article.
CONCLUSION: More than 60% of patients with GPA/MPA achieved prolonged remission, which was associated with better long-term outcomes. In contrast, prolonged LDAS correlated with increased damage accrual and was not a sufficient treatment target....
CONCLUSION: More than 60% of patients with GPA/MPA achieved prolonged remission, which was associated with better long-term outcomes. …
A highly virulent variant of HIV-1 circulating in the Netherlands.
Wymant C, Bezemer D, Blanquart F, Ferretti L, Gall A, Hall M, Golubchik T, Bakker M, Ong SH, Zhao L, Bonsall D, de Cesare M, MacIntyre-Cockett G, Abeler-Dörner L, Albert J, Bannert N, Fellay J, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Laeyendecker O, Meyer L, Porter K, Ristola M, van Sighem A, Berkhout B, Kellam P, Cornelissen M, Reiss P, Fraser C; Netherlands ATHENA HIV Observational Cohort†; BEEHIVE Collaboration†. Wymant C, et al. Science. 2022 Feb 4;375(6580):540-545. doi: 10.1126/science.abk1688. Epub 2022 Feb 3. Science. 2022. PMID: 35113714 Free article.
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expected to be reached, on average, 9 months after diagnosis for individuals in their thirties with this variant. Age, sex, suspected mode of trans …
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expecte …
Management of severe renal disease in anti-neutrophil-cytoplasmic-antibody-associated vasculitis: the place of rituximab and plasma exchange?
Morel P, Karras A, Porcher R, Belenfant X, Audard V, Rafat C, Hanouna G, Beaudreuil S, Vilain C, Hummel A, Terrier B, Pillebout E, Groh M, Jouenne R, Dhote R, Fain O, Ponsoye M, Noel N, Limal N, Puéchal X, Le Jeunne C, Guillevin L, Mouthon L, Régent A. Morel P, et al. Among authors: guillevin l. Rheumatology (Oxford). 2022 Oct 6;61(10):4056-4064. doi: 10.1093/rheumatology/keac046. Rheumatology (Oxford). 2022. PMID: 35108368
In patients receiving CYC induction regimen, the addition of PE conferred short-term benefits with higher dialysis-free rate at M12....
In patients receiving CYC induction regimen, the addition of PE conferred short-term benefits with higher dialysis-free rate at M12.. …
Localized versus systemic granulomatosis with polyangiitis: data from the French Vasculitis Study Group Registry.
Iudici M, Pagnoux C, Courvoisier DS, Cohen P, Néel A, Aouba A, Lifermann F, Ruivard M, Aumaître O, Bonnotte B, Maurier F, Le Gallou T, Hachulla E, Karras A, Khouatra C, Jourde-Chiche N, Viallard JF, Blanchard-Delaunay C, Godmer P, Le Quellec A, Quéméneur T, de Moreuil C, Régent A, Terrier B, Mouthon L, Guillevin L, Puéchal X; French Vasculitis Study Group. Iudici M, et al. Among authors: guillevin l. Rheumatology (Oxford). 2022 May 30;61(6):2464-2471. doi: 10.1093/rheumatology/keab719. Rheumatology (Oxford). 2022. PMID: 34542599
L-GPA and S-GPA patients' characteristics at diagnosis and long-term outcomes were analysed and compared. RESULTS: Among the 795 Registry patients, 79 (10%) had L-GPA. ...
L-GPA and S-GPA patients' characteristics at diagnosis and long-term outcomes were analysed and compared. RESULTS: Among the 795 Regi …
Revisiting characteristics, treatment and outcome of cardiomyopathy in eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss).
Sartorelli S, Chassagnon G, Cohen P, Dunogué B, Puéchal X, Régent A, Mouthon L, Guillevin L, Terrier B; French Vasculitis Study Group (FVSG). Sartorelli S, et al. Among authors: guillevin l. Rheumatology (Oxford). 2022 Mar 2;61(3):1175-1184. doi: 10.1093/rheumatology/keab514. Rheumatology (Oxford). 2022. PMID: 34156464
CONCLUSION: Specific cardiomyopathy is frequent in EGPA, especially in ANCA-negative patients with high eosinophil counts. Long-term outcome was better than previously reported. Abnormal ECG and LGE on CMRI were associated with the occurrence of MACEs....
CONCLUSION: Specific cardiomyopathy is frequent in EGPA, especially in ANCA-negative patients with high eosinophil counts. Long-term …
123 results