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Contrast-Enhanced Ultrasound after Endovascular Aortic Repair: Supplement and Potential Substitute for CT in Early- and Long-Term Follow-Up.
Morell-Hofert D, Gruber L, Gruber H, Glodny B, Gruber I, Loizides A. Morell-Hofert D, et al. Among authors: gruber h. Ann Vasc Surg. 2024 May;102:9-16. doi: 10.1016/j.avsg.2023.11.040. Epub 2024 Jan 30. Ann Vasc Surg. 2024. PMID: 38301847
CONCLUSIONS: CEUS should be considered a valid complementary method to CTA in the lifelong surveillance after EVAR. As type II endoleaks seem to be a common early-term, sometimes spontaneously resolving complication that can potentially be missed by CTA, we suggest combine …
CONCLUSIONS: CEUS should be considered a valid complementary method to CTA in the lifelong surveillance after EVAR. As type II endoleaks see …
Circulating Gal-3 and sST2 are associated with acute exercise-induced sustained endothelial activation: Possible relevance for fibrosis development?
Kröpfl JM, Beltrami FG, Gruber HJ, Schmidt-Trucksäss A, Dieterle T, Spengler CM. Kröpfl JM, et al. Among authors: gruber hj. Exp Physiol. 2023 Oct;108(10):1259-1267. doi: 10.1113/EP091277. Epub 2023 Aug 12. Exp Physiol. 2023. PMID: 37572028 Free PMC article.
Long-term, intense endurance exercise training can occasionally induce endothelial micro-damage and cardiac fibrosis. ...The importance of acute exercise-induced vascular resistances and cardiac contractility for the release of fibrotic biomarkers and any long-term
Long-term, intense endurance exercise training can occasionally induce endothelial micro-damage and cardiac fibrosis. ...The importan …
The impact of moderate endurance exercise on cardiac telomeres and cardiovascular remodeling in obese rats.
Semeraro MD, Beltrami AP, Kharrat F, Almer G, Sedej S, Renner W, Gruber HJ, Curcio F, Herrmann M. Semeraro MD, et al. Among authors: gruber hj. Front Cardiovasc Med. 2023 Jan 6;9:1080077. doi: 10.3389/fcvm.2022.1080077. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36684585 Free PMC article.
CONCLUSION: HFD-induced obesity showed no effects on myocardial telomeres and induced only mild morphologic alterations. Summarized, long-term moderate endurance exercise partially reverses HFD-induced effects but may even trigger cardiac remodeling in the context of obesi …
CONCLUSION: HFD-induced obesity showed no effects on myocardial telomeres and induced only mild morphologic alterations. Summarized, long- …
Long-term persistence of HCV resistance-associated substitutions after DAA treatment failure.
Dietz J, Müllhaupt B, Buggisch P, Graf C, Peiffer KH, Matschenz K, Schattenberg JM, Antoni C, Mauss S, Niederau C, Discher T, Trauth J, Dultz G, Schulze Zur Wiesch J, Piecha F, Klinker H, Müller T, Berg T, Neumann-Haefelin C, Berg CP, Zeuzem S, Sarrazin C; German HCV Resistance Study Group; University Hospitals; Academic Hospitals; Local study sites (private practices), Germany. Dietz J, et al. J Hepatol. 2023 Jan;78(1):57-66. doi: 10.1016/j.jhep.2022.08.016. Epub 2022 Aug 27. J Hepatol. 2023. PMID: 36031158
BACKGROUND & AIMS: Data on the long-term persistence of HCV resistance-associated substitutions (RASs) after treatment with direct-acting antivirals (DAAs) are limited. ...Different patterns of RAS persistence according to HCV subtype could have implications for retrea …
BACKGROUND & AIMS: Data on the long-term persistence of HCV resistance-associated substitutions (RASs) after treatment with direc …
Acute Exercise in Hypobaric Hypoxia Attenuates Endothelial Shedding in Subjects Unacclimatized to High Altitudes.
Kröpfl JM, Kammerer T, Faihs V, Gruber HJ, Stutz J, Rehm M, Stelzer I, Schäfer ST, Spengler CM. Kröpfl JM, et al. Among authors: gruber hj. Front Physiol. 2020 Feb 4;10:1632. doi: 10.3389/fphys.2019.01632. eCollection 2019. Front Physiol. 2020. PMID: 32116736 Free PMC article.
These results provide information to better understand the endothelium and immature immune system during an active, short-term sojourn at high altitude....
These results provide information to better understand the endothelium and immature immune system during an active, short-term sojour …
Relative telomere length and prostate cancer mortality.
Renner W, Krenn-Pilko S, Gruber HJ, Herrmann M, Langsenlehner T. Renner W, et al. Among authors: gruber hj. Prostate Cancer Prostatic Dis. 2018 Nov;21(4):579-583. doi: 10.1038/s41391-018-0068-3. Epub 2018 Aug 6. Prostate Cancer Prostatic Dis. 2018. PMID: 30082901
Aim of the present study was to analyze the prognostic value of leukocyte relative telomere (RTL) length in long-term prostate cancer (PCa) mortality. METHODS: Blood samples of PCa patients were obtained before initiation of radiotherapy. ...
Aim of the present study was to analyze the prognostic value of leukocyte relative telomere (RTL) length in long-term prostate cancer …
A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models.
Yagiz K, Rodriguez-Aguirre ME, Lopez Espinoza F, Montellano TT, Mendoza D, Mitchell LA, Ibanez CE, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. Yagiz K, et al. Among authors: gruber he. Mol Ther Oncolytics. 2017 Dec 5;8:14-26. doi: 10.1016/j.omto.2017.12.001. eCollection 2018 Mar 30. Mol Ther Oncolytics. 2017. PMID: 29322091 Free PMC article.
In brain tumor models, this treatment induces systemic anti-tumor immune responses and long-term immune-mediated survival. Phase 1 Toca 511 and Toca FC (extended-release 5-FC) clinical trials in patients with recurrent high-grade glioma show durable complete responses and …
In brain tumor models, this treatment induces systemic anti-tumor immune responses and long-term immune-mediated survival. Phase 1 To …
Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.
Hiraoka K, Inagaki A, Kato Y, Huang TT, Mitchell LA, Kamijima S, Takahashi M, Matsumoto H, Hacke K, Kruse CA, Ostertag D, Robbins JM, Gruber HE, Jolly DJ, Kasahara N. Hiraoka K, et al. Among authors: gruber he. Neuro Oncol. 2017 Jul 1;19(7):918-929. doi: 10.1093/neuonc/nox038. Neuro Oncol. 2017. PMID: 28387831 Free PMC article.
RESULTS: In both models, a single injection of replicating vector followed by prodrug administration achieved long-term survival benefit. In the immunodeficient model, tumors recurred repeatedly, but bioluminescence imaging of tumors enabled tailored scheduling of multicyc …
RESULTS: In both models, a single injection of replicating vector followed by prodrug administration achieved long-term survival bene …
42 results