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International Society of Urological Pathology (ISUP) Gleason Grade Groups stratify outcomes in the CHHiP Phase 3 prostate radiotherapy trial.
Dearnaley D, Griffin CL, Silva P, Wilkins A, Stuttle C, Syndikus I, Hassan S, Pugh J, Cruickshank C, Hall E, Corbishley CM. Dearnaley D, et al. Among authors: griffin cl. BJU Int. 2024 Feb;133(2):179-187. doi: 10.1111/bju.16133. Epub 2023 Aug 7. BJU Int. 2024. PMID: 37463104 Clinical Trial.
Patients upgraded from GGG 2 to GGG 3 using worst biopsy GS segregate with GGG 3 on long-term follow-up. We recommend that both overall and worst GS be used to derive GGG....
Patients upgraded from GGG 2 to GGG 3 using worst biopsy GS segregate with GGG 3 on long-term follow-up. We recommend that both overa …
Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy.
Dowdell A, Marsland M, Faulkner S, Gedye C, Lynam J, Griffin CP, Marsland J, Jiang CC, Hondermarck H. Dowdell A, et al. Among authors: griffin cp. FASEB Bioadv. 2023 Mar 13;5(5):211-220. doi: 10.1096/fba.2022-00141. eCollection 2023 May. FASEB Bioadv. 2023. PMID: 37151848 Free PMC article.
GBM cells resistant to TMZ were also responsive to MKC-3946 and the long-term inhibitory effect of MKC-3946 was confirmed by colony formation assay. ...
GBM cells resistant to TMZ were also responsive to MKC-3946 and the long-term inhibitory effect of MKC-3946 was confirmed by colony f …
Post-traumatic amnesia.
Parker TD, Rees R, Rajagopal S, Griffin C, Goodliffe L, Dilley M, Jenkins PO. Parker TD, et al. Among authors: griffin c. Pract Neurol. 2022 Apr;22(2):129-137. doi: 10.1136/practneurol-2021-003056. Epub 2021 Dec 14. Pract Neurol. 2022. PMID: 34906998
In the acute setting, post-traumatic amnesia may easily go unrecognised; this is problematic as it has important implications for both immediate management and for longer-term prognosis. We therefore recommend its careful clinical assessment and prospective evaluation usin …
In the acute setting, post-traumatic amnesia may easily go unrecognised; this is problematic as it has important implications for both immed …
A criteria-based rehabilitation program for chronic mid-portion Achilles tendinopathy: study protocol for a randomised controlled trial.
Griffin C, Daniels K, Hill C, Franklyn-Miller A, Morin JB. Griffin C, et al. BMC Musculoskelet Disord. 2021 Aug 14;22(1):695. doi: 10.1186/s12891-021-04553-6. BMC Musculoskelet Disord. 2021. PMID: 34391384 Free PMC article.
Secondary aims will be to assess changes in calf strength, reactive strength, and lower limb running and forward hop biomechanics over the course of a 12-week rehabilitation program, and long-term follow-up investigations. METHODS: Sixty eligible participants with chronic …
Secondary aims will be to assess changes in calf strength, reactive strength, and lower limb running and forward hop biomechanics over the c …
Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS.
Li LM, Dilley MD, Carson A, Twelftree J, Hutchinson PJ, Belli A, Betteridge S, Cooper PN, Griffin CM, Jenkins PO, Liu C, Sharp DJ, Sylvester R, Wilson MH, Turner MS, Greenwood R. Li LM, et al. Among authors: griffin cm. Clin Med (Lond). 2021 Mar;21(2):e198-e205. doi: 10.7861/clinmed.2020-0336. Clin Med (Lond). 2021. PMID: 33762387 Free PMC article.
This results in suboptimal rehabilitation outcome and avoidable detrimental chronic effects on patients' recovery. This worsens long-term disability, and magnifies costs to the individual and society. ...An expert-led, integrated care pathway is needed to deliver accurate …
This results in suboptimal rehabilitation outcome and avoidable detrimental chronic effects on patients' recovery. This worsens long-term …
Core Fermentation (CoFe) granules focus coordinated glycolytic mRNA localization and translation to fuel glucose fermentation.
Morales-Polanco F, Bates C, Lui J, Casson J, Solari CA, Pizzinga M, Forte G, Griffin C, Garner KEL, Burt HE, Dixon HL, Hubbard S, Portela P, Ashe MP. Morales-Polanco F, et al. Among authors: griffin c. iScience. 2021 Jan 19;24(2):102069. doi: 10.1016/j.isci.2021.102069. eCollection 2021 Feb 19. iScience. 2021. PMID: 33554071 Free PMC article.
Indeed, the degree of fermentation required by cells is intrinsically connected to the extent of mRNA localization to granules. On this basis, we term these granules, core fermentation (CoFe) granules; they appear to represent translation factories, allowing high-level coo …
Indeed, the degree of fermentation required by cells is intrinsically connected to the extent of mRNA localization to granules. On this basi …
Linkage of the CHHiP randomised controlled trial with primary care data: a study investigating ways of supplementing cancer trials and improving evidence-based practice.
Lemanska A, Byford RC, Cruickshank C, Dearnaley DP, Ferreira F, Griffin C, Hall E, Hinton W, de Lusignan S, Sherlock J, Faithfull S. Lemanska A, et al. Among authors: griffin c. BMC Med Res Methodol. 2020 Jul 25;20(1):198. doi: 10.1186/s12874-020-01078-9. BMC Med Res Methodol. 2020. PMID: 32711460 Free PMC article. Clinical Trial.
Data recorded in primary care are a rich resource and linkage could provide near real-time information to supplement trials and an efficient and cost-effective mechanism for long-term follow-up. In addition, standardised primary care data extracts could form part of RCT re …
Data recorded in primary care are a rich resource and linkage could provide near real-time information to supplement trials and an efficient …
Long-Term Impact of Vascular Surgery Stress on Frail Older Patients.
Gilbertson EA, Bailey TR, Kraiss LW, Griffin CL, Smith BK, Sarfati M, Beckstrom J, Brooke BS. Gilbertson EA, et al. Among authors: griffin cl. Ann Vasc Surg. 2021 Jan;70:9-19. doi: 10.1016/j.avsg.2020.06.048. Epub 2020 Jun 27. Ann Vasc Surg. 2021. PMID: 32603848
BACKGROUND: Frailty is a syndrome where the ability to cope with acute physiological stress is compromised, although it is unclear what impact this stress has on long-term outcomes. Vascular-Physiological and Operative Severity Score for enumeration of Mortality and Morbid …
BACKGROUND: Frailty is a syndrome where the ability to cope with acute physiological stress is compromised, although it is unclear what impa …
The effect of social preference on academic diligence in adolescence.
Andrews JL, Foulkes L, Griffin C, Blakemore SJ. Andrews JL, et al. Among authors: griffin c. R Soc Open Sci. 2019 Sep 11;6(9):190165. doi: 10.1098/rsos.190165. eCollection 2019 Sep. R Soc Open Sci. 2019. PMID: 31598279 Free PMC article.
In the current study, we were interested in whether adolescents show a preference for social stimuli compared with non-social stimuli in the context of academic diligence, that is, the ability to expend effort on tedious tasks that have long-term benefits. Forty-five femal …
In the current study, we were interested in whether adolescents show a preference for social stimuli compared with non-social stimuli in the …
Non-technical skills: a review of training and evaluation in urology.
Griffin C, Aydın A, Brunckhorst O, Raison N, Khan MS, Dasgupta P, Ahmed K. Griffin C, et al. World J Urol. 2020 Jul;38(7):1653-1661. doi: 10.1007/s00345-019-02920-6. Epub 2019 Sep 17. World J Urol. 2020. PMID: 31529246 Free PMC article. Review.
CONCLUSION: To move forward, studies should combine tried and tested learning techniques into a curriculum covering all training levels, which should then be validated and followed up long term to ensure a positive impact on patient safety....
CONCLUSION: To move forward, studies should combine tried and tested learning techniques into a curriculum covering all training levels, whi …
65 results