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Long-Term Outcomes of Resynchronization-Defibrillation for Heart Failure.
Sapp JL, Sivakumaran S, Redpath CJ, Khan H, Parkash R, Exner DV, Healey JS, Thibault B, Sterns LD, Lam NHN, Manlucu J, Mokhtar A, Sumner G, McKinlay S, Kimber S, Mondesert B, Talajic M, Rouleau J, McCarron CE, Wells G, Tang ASL; RAFT Long-Term Study Team. Sapp JL, et al. N Engl J Med. 2024 Jan 18;390(3):212-220. doi: 10.1056/NEJMoa2304542. N Engl J Med. 2024. PMID: 38231622 Clinical Trial.
We assessed long-term outcomes among patients at the eight highest-enrolling participating sites. ...RESULTS: The trial enrolled 1798 patients, of whom 1050 were included in the long-term survival trial; the median duration of follow-up for the 1050 patients was 7.7 …
We assessed long-term outcomes among patients at the eight highest-enrolling participating sites. ...RESULTS: The trial enrolled 1798 …
The inflammatory response to birth requires MyD88 and is driven by both mother and offspring.
Gray JM, Major K, Castillo-Ruiz A, Shipley M, Gangappa S, Forger NG. Gray JM, et al. Brain Behav Immun. 2024 Jan;115:617-630. doi: 10.1016/j.bbi.2023.11.011. Epub 2023 Nov 13. Brain Behav Immun. 2024. PMID: 37967662
Birth is an inflammatory event for the newborn, characterized by elevations in interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF)-alpha peripherally and/or centrally, as well as changes in brain microglia. ...Thus, the inflammatory response previously described in …
Birth is an inflammatory event for the newborn, characterized by elevations in interleukin (IL)-6, IL-10, and tumor necrosis factor ( …
Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.
Healey JS, Lopes RD, Granger CB, Alings M, Rivard L, McIntyre WF, Atar D, Birnie DH, Boriani G, Camm AJ, Conen D, Erath JW, Gold MR, Hohnloser SH, Ip J, Kautzner J, Kutyifa V, Linde C, Mabo P, Mairesse G, Benezet Mazuecos J, Cosedis Nielsen J, Philippon F, Proietti M, Sticherling C, Wong JA, Wright DJ, Zarraga IG, Coutts SB, Kaplan A, Pombo M, Ayala-Paredes F, Xu L, Simek K, Nevills S, Mian R, Connolly SJ; ARTESIA Investigators. Healey JS, et al. N Engl J Med. 2024 Jan 11;390(2):107-117. doi: 10.1056/NEJMoa2310234. Epub 2023 Nov 12. N Engl J Med. 2024. PMID: 37952132 Clinical Trial.
BACKGROUND: Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually be detected only by long-term continuous monitoring with pacemakers or defibrillators. Subclinical atrial fibrillation is associated with an increased risk of stroke by a factor o …
BACKGROUND: Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually be detected only by long-term continuou …
Loss of mfsd8 alters the secretome during Dictyostelium aggregation.
Huber RJ, Gray J, Kim WD. Huber RJ, et al. Among authors: gray j. Eur J Cell Biol. 2023 Dec;102(4):151361. doi: 10.1016/j.ejcb.2023.151361. Epub 2023 Sep 19. Eur J Cell Biol. 2023. PMID: 37742391 Free article.
Most proteins were present in increased amounts in mfsd8(-) conditioned buffer compared to WT indicating that loss of mfsd8 deregulates protein secretion and/or causes the release of proteins not normally secreted by WT cells. GO term enrichment analyses showed that many o …
Most proteins were present in increased amounts in mfsd8(-) conditioned buffer compared to WT indicating that loss of mfsd8 deregulates prot …
Review: Targeting EZH2 in neuroblastoma.
Gao J, Fosbrook C, Gibson J, Underwood TJ, Gray JC, Walters ZS. Gao J, et al. Among authors: gray jc. Cancer Treat Rev. 2023 Sep;119:102600. doi: 10.1016/j.ctrv.2023.102600. Epub 2023 Jul 13. Cancer Treat Rev. 2023. PMID: 37467626 Free article. Review.
The majority of patients are considered to have high-risk neuroblastoma, for which the long-term survival is less than 50%. Current treatments combine surgical resection, chemotherapy, stem cell transplantation, radiotherapy, anti-GD2 based immunotherapy as well as the dif …
The majority of patients are considered to have high-risk neuroblastoma, for which the long-term survival is less than 50%. Current t …
Splanchnic Nerve Modulation Effects on Surrogate Measures of Venous Capacitance.
Kittipibul V, Ganesh A, Coburn A, Coyne BJ, Gray JM, Molinger J, Ray N, Podgoreanu M, McCartney SL, Mamoun N, Fitzhugh RC, Lurz P, Green CL, Hernandez AF, Patel MR, Fudim M. Kittipibul V, et al. Among authors: gray jm. J Am Heart Assoc. 2023 Jul 18;12(14):e028780. doi: 10.1161/JAHA.122.028780. Epub 2023 Jul 14. J Am Heart Assoc. 2023. PMID: 37449573 Free PMC article. Clinical Trial.
Minimally invasive measures of venous capacitance could serve as markers of successful SNM. Long-term effects of SNM on venous capacitance warrant further investigation for heart failure management. ...
Minimally invasive measures of venous capacitance could serve as markers of successful SNM. Long-term effects of SNM on venous capaci …
Diagnostic profiles associated with long-term opioid therapy in active duty servicemembers.
Dufour S, Banaag A, Schoenfeld AJ, Adams RS, Koehlmoos TP, Gray JC. Dufour S, et al. Among authors: gray jc. PM R. 2024 Jan;16(1):14-24. doi: 10.1002/pmrj.12994. Epub 2023 Jul 26. PM R. 2024. PMID: 37162022 Free PMC article.
Logistic regression measured the odds of these classes receiving long-term opioid therapy. SETTING: All electronic health data under the TRICARE network. ...We hypothesized that LCA classes characterized by high-risk contraindications would have significantly higher odds o …
Logistic regression measured the odds of these classes receiving long-term opioid therapy. SETTING: All electronic health data under …
Goals and goal perceptions in patients with advanced stage lung cancer: a mixed methods study.
Hyland KA, Oswald LB, Reblin M, Small BJ, Gray JE, Jim HSL, Jacobsen PB. Hyland KA, et al. Among authors: gray je. Support Care Cancer. 2023 May 1;31(5):314. doi: 10.1007/s00520-023-07745-z. Support Care Cancer. 2023. PMID: 37126099 Free PMC article.
On average, participants considered their goals to be attainable, perceived a high degree of control over reaching goals, anticipated making "some" progress in the short term, and perceived a high likelihood of reaching goals in the future. ...
On average, participants considered their goals to be attainable, perceived a high degree of control over reaching goals, anticipated making …
Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide.
Karvouni M, Vidal-Manrique M, Susek KH, Hussain A, Gilljam M, Zhang Y, Gray JD, Lund J, Kaufmann G, Ljunggren HG, Ji H, Lundqvist A, Wagner AK, Guo W, Alici E. Karvouni M, et al. Among authors: gray jd. Cytotherapy. 2023 Jul;25(7):763-772. doi: 10.1016/j.jcyt.2023.03.006. Epub 2023 Apr 11. Cytotherapy. 2023. PMID: 37055320 Free article.
Here, we present an alternative approach by harnessing the CD38(dim) phenotype occurring during long-term cytokine stimulation of primary NK cells. METHODS: Primary NK cells were expanded from peripheral blood mononuclear cells by long-term IL-2 stimulation. ...
Here, we present an alternative approach by harnessing the CD38(dim) phenotype occurring during long-term cytokine stimulation of pri …
248 results