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Cocoa Consumption Decreases Oxidative Stress, Proinflammatory Mediators and Lipid Peroxidation in Healthy Subjects: A Randomized Placebo-Controlled Dose-Response Clinical Trial.
Grassi D, Mai F, De Feo M, Barnabei R, Carducci A, Desideri G, Necozione S, Allegaert L, Bernaert H, Ferri C. Grassi D, et al. High Blood Press Cardiovasc Prev. 2023 May;30(3):219-225. doi: 10.1007/s40292-023-00571-8. Epub 2023 Mar 28. High Blood Press Cardiovasc Prev. 2023. PMID: 36976481 Free PMC article. Clinical Trial.
RESULTS: Compared with flavonoid-free cocoa control, cocoa reduced sICAM-1 mean values [from 1190.2 to 1123.0; 906.3; 741.7 and 625.6 pg/mL (p = 0.0198 and p = 0.0016, for 500 and 800 mg respectively], sCD40L mean values [from 218.8 to 210.2; 165.5; 134.5 and 128.4 pg/mL (p = 0.0 …
RESULTS: Compared with flavonoid-free cocoa control, cocoa reduced sICAM-1 mean values [from 1190.2 to 1123.0; 906.3; 741.7 and 625.6 pg/mL …
Acute and Long Term Effects of a Nutraceutical Combination on Lipid Profile, Glucose Metabolism and Vascular Function in Patients with Dyslipidaemia with and Without Cigarette Smoking.
Grassi D, Necozione S, Desideri G, Abballe S, Mai F, De Feo M, Carducci A, Ferri C. Grassi D, et al. High Blood Press Cardiovasc Prev. 2021 Sep;28(5):483-491. doi: 10.1007/s40292-021-00468-4. Epub 2021 Sep 13. High Blood Press Cardiovasc Prev. 2021. PMID: 34519016 Free PMC article.
Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve Study.
Crosta F, Stefani A, Melani F, Fabrizzi P, Nizzardo A, Grassi D, Bocale R, Necozione S, Lombardi F, Castelli V, Cicero AFG, Cimini A, Ferri C, Desideri G. Crosta F, et al. Among authors: grassi d. Nutrients. 2020 Dec 27;13(1):56. doi: 10.3390/nu13010056. Nutrients. 2020. PMID: 33375429 Free PMC article. Clinical Trial.
Blocking of Estradiol Receptors ERα, ERβ and GPER During Development, Differentially Alters Energy Metabolism in Male and Female Rats.
Carrillo B, Collado P, Díaz F, Chowen JA, Grassi D, Pinos H. Carrillo B, et al. Among authors: grassi d. Neuroscience. 2020 Feb 1;426:59-68. doi: 10.1016/j.neuroscience.2019.11.008. Epub 2019 Dec 2. Neuroscience. 2020. PMID: 31805254
Estrogen receptors (ER) alpha, ERbeta and GPER were blocked by their specific antagonists MPP, PHTPP and G15, respectively, from postnatal day (P) 1 (the day of birth) to P5 or from P5 to P13. Physiological parameters such as body weight, fat depots and caloric intake were …
Estrogen receptors (ER) alpha, ERbeta and GPER were blocked by their specific antagonists MPP, PHTPP and G15, respectively, from postnatal d …
Short-term supplementation with flavanol-rich cocoa improves lipid profile, antioxidant status and positively influences the AA/EPA ratio in healthy subjects.
Davinelli S, Corbi G, Zarrelli A, Arisi M, Calzavara-Pinton P, Grassi D, De Vivo I, Scapagnini G. Davinelli S, et al. Among authors: grassi d. J Nutr Biochem. 2018 Nov;61:33-39. doi: 10.1016/j.jnutbio.2018.07.011. Epub 2018 Aug 14. J Nutr Biochem. 2018. PMID: 30179727 Clinical Trial.
We evaluated the short-term effects of a flavanol-rich cocoa (FRC) on lipid profile and selected oxidative stress biomarkers such as oxidized low-density lipoprotein (oxLDL), glutathione (GSH), and F(2)-isoprostane. ...
We evaluated the short-term effects of a flavanol-rich cocoa (FRC) on lipid profile and selected oxidative stress biomarkers such as …
Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study.
Raparelli V, Pastori D, Pignataro SF, Vestri AR, Pignatelli P, Cangemi R, Proietti M, Davì G, Hiatt WR, Lip GYH, Corazza GR, Perticone F, Violi F, Basili S; ARAPACIS Study Collaborators. Raparelli V, et al. Intern Emerg Med. 2018 Aug;13(5):651-660. doi: 10.1007/s11739-018-1835-9. Epub 2018 Mar 26. Intern Emerg Med. 2018. PMID: 29582316
COPD is an independent predictor of MACE, CV death and all-cause death during a long-term follow-up of NVAF patients....
COPD is an independent predictor of MACE, CV death and all-cause death during a long-term follow-up of NVAF patients....
Effects of a Novel Fixed Combination of Nutraceuticals on Serum Uric Acid Concentrations and the Lipid Profile in Asymptomatic Hyperuricemic Patients : Results from the PICONZ-UA Study.
Rozza F, Trimarco V, Izzo R, Grassi D, Ferri C. Rozza F, et al. Among authors: grassi d. High Blood Press Cardiovasc Prev. 2016 Dec;23(4):381-386. doi: 10.1007/s40292-016-0168-x. Epub 2016 Sep 19. High Blood Press Cardiovasc Prev. 2016. PMID: 27644242 Clinical Trial.
CONCLUSIONS: This study represents the first demonstration that a short-term therapy with a fixed combination of different natural substances can significantly reduce serum uric acid concentrations in asymptomatic hyperuricemic patients, with no side effects and a signific …
CONCLUSIONS: This study represents the first demonstration that a short-term therapy with a fixed combination of different natural su …
Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature.
Giorgini P, Di Giosia P, Grassi D, Rubenfire M, Brook RD, Ferri C. Giorgini P, et al. Among authors: grassi d. Curr Pharm Des. 2016;22(1):28-51. doi: 10.2174/1381612822666151109111712. Curr Pharm Des. 2016. PMID: 26548310 Review.
Epidemiological findings demonstrate that particulate pollutants cause significant increases in BP parameters in relation to both short and long-term exposures, with robust evidence for exposures to PM2.5. Moreover, recent epidemiological studies suggest a positive associa …
Epidemiological findings demonstrate that particulate pollutants cause significant increases in BP parameters in relation to both short and …
Cocoa, blood pressure, and cardiovascular health.
Ferri C, Desideri G, Ferri L, Proietti I, Di Agostino S, Martella L, Mai F, Di Giosia P, Grassi D. Ferri C, et al. Among authors: grassi d. J Agric Food Chem. 2015 Nov 18;63(45):9901-9. doi: 10.1021/acs.jafc.5b01064. Epub 2015 Jul 13. J Agric Food Chem. 2015. PMID: 26125676 Review.
Previous meta-analyses have shown that cocoa-rich foods may reduce blood pressure. Long-term trials investigating the effect of cocoa products are needed to determine whether or not blood pressure is reduced on a chronic basis by daily ingestion of cocoa. Furthermore, long …
Previous meta-analyses have shown that cocoa-rich foods may reduce blood pressure. Long-term trials investigating the effect of cocoa …
17 results