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Aquagenic wrinkling of the palms in cystic fibrosis patients treated with ivacaftor.
Jacobi E, Solomon M, Avolio J, Shaw M, Gonska T, Ratjen F, Grasemann H. Jacobi E, et al. Among authors: grasemann h. J Cyst Fibros. 2022 Mar;21(2):e102-e105. doi: 10.1016/j.jcf.2022.01.005. Epub 2022 Jan 19. J Cyst Fibros. 2022. PMID: 35063397 Free article.
Aquagenic wrinkling of palms (AWP) in cystic fibrosis (CF) patients and common CFTR mutations is recognized as a frequent symptom of the disease. The long-term effect of CFTR targeting therapy on AWP has not been studied. ...
Aquagenic wrinkling of palms (AWP) in cystic fibrosis (CF) patients and common CFTR mutations is recognized as a frequent symptom of the dis …
Neuropsychological outcomes following pediatric lung transplantation.
Gold A, Young JM, Solomon M, Grasemann H. Gold A, et al. Among authors: grasemann h. Pediatr Pulmonol. 2020 Sep;55(9):2427-2436. doi: 10.1002/ppul.24915. Epub 2020 Jul 6. Pediatr Pulmonol. 2020. PMID: 32567252
OBJECTIVE: Lung transplantation (LTx) is a treatment option for eligible children with end-stage pulmonary diseases. Improving our understanding of longer-term developmental outcomes in pediatric LTx recipients is important for strategized interventions targeting cognitive …
OBJECTIVE: Lung transplantation (LTx) is a treatment option for eligible children with end-stage pulmonary diseases. Improving our understan …
Lung transplantation for cystic fibrosis.
Yeung JC, Machuca TN, Chaparro C, Cypel M, Stephenson AL, Solomon M, Saito T, Binnie M, Chow CW, Grasemann H, Pierre AF, Yasufuku K, de Perrot M, Donahoe LL, Tikkanen J, Martinu T, Waddell TK, Tullis E, Singer LG, Keshavjee S. Yeung JC, et al. Among authors: grasemann h. J Heart Lung Transplant. 2020 Jun;39(6):553-560. doi: 10.1016/j.healun.2020.02.010. Epub 2020 Feb 20. J Heart Lung Transplant. 2020. PMID: 32147452
CONCLUSIONS: Lung transplantation for CF provides excellent short- and long-term outcomes. These results strongly support lung transplantation as the standard of care for patients with CF having advanced lung disease....
CONCLUSIONS: Lung transplantation for CF provides excellent short- and long-term outcomes. These results strongly support lung transp …
L-Citrulline increases nitric oxide and improves control in obese asthmatics.
Holguin F, Grasemann H, Sharma S, Winnica D, Wasil K, Smith V, Cruse MH, Perez N, Coleman E, Scialla TJ, Que LG. Holguin F, et al. Among authors: grasemann h. JCI Insight. 2019 Dec 19;4(24):e131733. doi: 10.1172/jci.insight.131733. JCI Insight. 2019. PMID: 31714895 Free PMC article. Clinical Trial.
The changes in lung function or asthma control were not significantly associated with the changes before and after treatment in L-arginine/ADMA or FeNO.CONCLUSIONShort-term L-citrulline treatment improved asthma control and FeNO levels in obese asthmatics with low or norma …
The changes in lung function or asthma control were not significantly associated with the changes before and after treatment in L-arginine/A …
Long-term effect of CFTR modulator therapy on airway nitric oxide.
Grasemann H, Klingel M, Avolio J, Prentice C, Gonska T, Tullis E, Ratjen F. Grasemann H, et al. Eur Respir J. 2020 Jan 9;55(1):1901113. doi: 10.1183/13993003.01113-2019. Print 2020 Jan. Eur Respir J. 2020. PMID: 31601715 Free article. No abstract available.
Residential green space and pathways to term birth weight in the Canadian Healthy Infant Longitudinal Development (CHILD) Study.
Cusack L, Sbihi H, Larkin A, Chow A, Brook JR, Moraes T, Mandhane PJ, Becker AB, Azad MB, Subbarao P, Kozyrskyj A, Takaro TK, Sears MR, Turvey SE, Hystad P; CHILD Study Investigators. Cusack L, et al. Int J Health Geogr. 2018 Dec 4;17(1):43. doi: 10.1186/s12942-018-0160-x. Int J Health Geogr. 2018. PMID: 30514315 Free PMC article.
Linear regression was used to assess associations between green space and term birth weight adjusting first for a comprehensive set of confounding factors and then incrementally for pathway variables. RESULTS: Fully adjusted models showed non-statistically significa …
Linear regression was used to assess associations between green space and term birth weight adjusting first for a comprehensiv …
Cesarean Section, Formula Feeding, and Infant Antibiotic Exposure: Separate and Combined Impacts on Gut Microbial Changes in Later Infancy.
Yasmin F, Tun HM, Konya TB, Guttman DS, Chari RS, Field CJ, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR; CHILD Study Investigators; Scott JA, Dinu I, Kozyrskyj AL. Yasmin F, et al. Front Pediatr. 2017 Sep 26;5:200. doi: 10.3389/fped.2017.00200. eCollection 2017. Front Pediatr. 2017. PMID: 29018787 Free PMC article.
Gut microbiota of 166 full-term infants in the Canadian Healthy Infant Longitudinal Development birth cohort were profiled using 16S high-throughput gene sequencing. Infants were placed into groups according to mutually exclusive combinations of birth mode (v …
Gut microbiota of 166 full-term infants in the Canadian Healthy Infant Longitudinal Development birth cohort were profiled usi …
Quality of life outcomes following pediatric lung transplantation.
Lazor T, Grasemann H, Solomon M, Anthony SJ. Lazor T, et al. Among authors: grasemann h. Pediatr Pulmonol. 2017 Nov;52(11):1495-1501. doi: 10.1002/ppul.23788. Epub 2017 Sep 14. Pediatr Pulmonol. 2017. PMID: 28910513
CONCLUSIONS: Findings highlight the importance of QoL outcomes when exploring LTx as a treatment option. Future research should explore long-term QoL outcomes post-LTx and examine standardized integration of patient-reported outcomes into clinical practice....
CONCLUSIONS: Findings highlight the importance of QoL outcomes when exploring LTx as a treatment option. Future research should explore long …
Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study.
Azad MB, Konya T, Persaud RR, Guttman DS, Chari RS, Field CJ, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Azad MB, et al. BJOG. 2016 May;123(6):983-93. doi: 10.1111/1471-0528.13601. Epub 2015 Sep 28. BJOG. 2016. PMID: 26412384
OBJECTIVE: Dysbiosis of the infant gut microbiota may have long-term health consequences. This study aimed to determine the impact of maternal intrapartum antibiotic prophylaxis (IAP) on infant gut microbiota, and to explore whether breastfeeding modifies these effects. .. …
OBJECTIVE: Dysbiosis of the infant gut microbiota may have long-term health consequences. This study aimed to determine the impact of …
Classification of childhood asthma phenotypes and long-term clinical responses to inhaled anti-inflammatory medications.
Howrylak JA, Fuhlbrigge AL, Strunk RC, Zeiger RS, Weiss ST, Raby BA; Childhood Asthma Management Program Research Group. Howrylak JA, et al. J Allergy Clin Immunol. 2014 May;133(5):1289-300, 1300.e1-12. doi: 10.1016/j.jaci.2014.02.006. J Allergy Clin Immunol. 2014. PMID: 24892144 Free PMC article. Clinical Trial.
RESULTS: We found 5 reproducible patient clusters that could be differentiated on the basis of 3 groups of features: atopic burden, degree of airway obstruction, and history of exacerbation. Cluster grouping predicted long-term asthma control, as measured by the need for o …
RESULTS: We found 5 reproducible patient clusters that could be differentiated on the basis of 3 groups of features: atopic burden, degree o …
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