A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages.
Nguyên-Trân VT, Kubalak SW, Minamisawa S, Fiset C, Wollert KC, Brown AB, Ruiz-Lozano P, Barrere-Lemaire S, Kondo R, Norman LW, Gourdie RG, Rahme MM, Feld GK, Clark RB, Giles WR, Chien KR.
Nguyên-Trân VT, et al. Among authors: gourdie rg.
Cell. 2000 Sep 1;102(5):671-82. doi: 10.1016/s0092-8674(00)00089-1.
Cell. 2000.
PMID: 11007485
Free article.
HF-1 b, an SP1 -related transcription factor, is preferentially expressed in the cardiac conduction system and ventricular myocytes in the heart. Mice deficient for HF-1 b survive to term and exhibit normal cardiac structure and function but display sudden cardiac death an …
HF-1 b, an SP1 -related transcription factor, is preferentially expressed in the cardiac conduction system and ventricular myocytes in the h …