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Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials.
Packer M, McMurray JJV, Krum H, Kiowski W, Massie BM, Caspi A, Pratt CM, Petrie MC, DeMets D, Kobrin I, Roux S, Swedberg K; ENABLE Investigators and Committees. Packer M, et al. JACC Heart Fail. 2017 May;5(5):317-326. doi: 10.1016/j.jchf.2017.02.021. JACC Heart Fail. 2017. PMID: 28449795 Free article. Review.
OBJECTIVES: The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure. BACKGROUND: Endothelin may play a role in heart failure, but …
OBJECTIVES: The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan …
Lack of adaptation from standing genetic variation despite the presence of putatively adaptive alleles in introduced sweet vernal grass (Anthoxanthum odoratum).
Gould B, Geber M. Gould B, et al. J Evol Biol. 2016 Jan;29(1):178-87. doi: 10.1111/jeb.12773. Epub 2015 Nov 19. J Evol Biol. 2016. PMID: 26468961 Free article.
In this study, we examined local adaptation to soil Al toxicity in the introduced range of sweet vernal grass (Anthoxanthum odoratum), and we genotyped populations for the presence of Al tolerance alleles previously identified at the long-term ecological Park Grass Experim …
In this study, we examined local adaptation to soil Al toxicity in the introduced range of sweet vernal grass (Anthoxanthum odoratum), and w …
De Novo Transcriptome Assembly and Identification of Gene Candidates for Rapid Evolution of Soil Al Tolerance in Anthoxanthum odoratum at the Long-Term Park Grass Experiment.
Gould B, McCouch S, Geber M. Gould B, et al. PLoS One. 2015 Jul 6;10(7):e0124424. doi: 10.1371/journal.pone.0124424. eCollection 2015. PLoS One. 2015. PMID: 26148203 Free PMC article.
Anthoxanthum has become locally adapted to differences in soil Al toxicity, which have developed there due to soil acidification from long-term experimental fertilizer treatments. In this study, we used transcriptome sequencing to identify Al stress responsive genes in Ant …
Anthoxanthum has become locally adapted to differences in soil Al toxicity, which have developed there due to soil acidification from long- …
Variation in soil aluminium tolerance genes is associated with local adaptation to soils at the Park Grass Experiment.
Gould B, McCouch S, Geber M. Gould B, et al. Mol Ecol. 2014 Dec;23(24):6058-72. doi: 10.1111/mec.12893. Epub 2014 Oct 21. Mol Ecol. 2014. PMID: 25145641
Studies of the wild grass Anthoxanthum odoratum at the long-term Park Grass Experiment (PGE, Harpenden, UK) document a well-known example of rapid plant evolution in response to environmental change. ...
Studies of the wild grass Anthoxanthum odoratum at the long-term Park Grass Experiment (PGE, Harpenden, UK) document a well-known exa …
Mean-reversion in income over feed cost margins: evidence and implications for managing margin risk by US dairy producers.
Bozic M, Newton J, Thraen CS, Gould BW. Bozic M, et al. Among authors: gould bw. J Dairy Sci. 2012 Dec;95(12):7417-28. doi: 10.3168/jds.2012-5818. Epub 2012 Oct 3. J Dairy Sci. 2012. PMID: 23040030 Free article.
What is apparent from the shapes of these term structures is that both in times when margins were exceptionally high and in times when they were disastrously low, market participants expected that a reversal back to average margin levels would not come quickly, but rather …
What is apparent from the shapes of these term structures is that both in times when margins were exceptionally high and in times whe …
Effect of transfusion therapy on transcranial Doppler ultrasonography velocities in children with sickle cell disease.
Kwiatkowski JL, Yim E, Miller S, Adams RJ; STOP 2 Study Investigators. Kwiatkowski JL, et al. Pediatr Blood Cancer. 2011 May;56(5):777-82. doi: 10.1002/pbc.22951. Epub 2010 Dec 23. Pediatr Blood Cancer. 2011. PMID: 21370410 Free PMC article.
CONCLUSION: Younger children with higher pre-transfusion hemoglobin levels and lower abnormal TCD velocities are most likely to have rapid normalization of TCD on transfusions. Long-term follow-up of children with persistently abnormal exams or worsening velocities on tran …
CONCLUSION: Younger children with higher pre-transfusion hemoglobin levels and lower abnormal TCD velocities are most likely to have rapid n …
Angiogenesis gene expression in mouse uterus during the common pathway of parturition.
Haddad R, Romero R, Gould BR, Tromp G, Gotsch F, Edwin SS, Zingg HH. Haddad R, et al. Among authors: gould br. Am J Obstet Gynecol. 2008 May;198(5):539.e1-8. doi: 10.1016/j.ajog.2007.11.021. Am J Obstet Gynecol. 2008. PMID: 18455529
STUDY DESIGN: Preterm pregnant mice (14.5 days of gestation) were treated with the following: (1) intrauterine injection of media; (2) intrauterine injection of heat-inactivated Escherichia coli; (3) ovariectomy; and (4) sham operation. Tissues from mice at term (19.5 days …
STUDY DESIGN: Preterm pregnant mice (14.5 days of gestation) were treated with the following: (1) intrauterine injection of media; (2) intra …
Effect of long-term olive oil dietary intervention on postprandial triacylglycerol and factor VII metabolism.
Roche HM, Zampelas A, Knapper JM, Webb D, Brooks C, Jackson KG, Wright JW, Gould BJ, Kafatos A, Gibney MJ, Williams CM. Roche HM, et al. Among authors: gould bj. Am J Clin Nutr. 1998 Sep;68(3):552-60. doi: 10.1093/ajcn/68.3.552. Am J Clin Nutr. 1998. PMID: 9734730 Clinical Trial.
This study used a single-blind, randomized, crossover design to investigate the relative effects of a long-term dietary olive oil intervention and a control [saturated fatty acid (SFA)-enriched] diet on postprandial triacylglycerol metabolism and factor VII activity. ...Th …
This study used a single-blind, randomized, crossover design to investigate the relative effects of a long-term dietary olive oil int …
Biological variation in glycated proteins.
Davie SJ, Whiting KL, Gould BJ. Davie SJ, et al. Among authors: gould bj. Ann Clin Biochem. 1993 May;30 ( Pt 3):260-4. doi: 10.1177/000456329303000306. Ann Clin Biochem. 1993. PMID: 8517608
The fructosamine assays therefore have significant advantages over the affinity chromatography methods as indices of medium-term glycaemic control....
The fructosamine assays therefore have significant advantages over the affinity chromatography methods as indices of medium-term glyc …
Aging and long-term ovariectomy alter the cytoarchitecture of the hypothalamic-preoptic area of the C57BL/6J mouse.
Miller MM, Gould BE, Nelson JF. Miller MM, et al. Among authors: gould be. Neurobiol Aging. 1989 Nov-Dec;10(6):683-90. doi: 10.1016/0197-4580(89)90005-5. Neurobiol Aging. 1989. PMID: 2628780
Long-term ovariectomy attenuates several neuroendocrine-dependent changes in reproductive function of aging female rodents, but the sites affected and underlying mechanisms are not known. ...Density of blood vessels increased strikingly in ARC (150%; p less than 0.05), and …
Long-term ovariectomy attenuates several neuroendocrine-dependent changes in reproductive function of aging female rodents, but the s …
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