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Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk; Cholesterol Treatment Trialists’ (CTT) Collaboration. Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk, et al. Lancet Diabetes Endocrinol. 2024 May;12(5):306-319. doi: 10.1016/S2213-8587(24)00040-8. Epub 2024 Mar 27. Lancet Diabetes Endocrinol. 2024. PMID: 38554713
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy. METHODS: We conducted a meta-analysis of individual participant data from randomised controlled trials of s …
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double …
Vitamin C deficiency alters the transcriptome of the rat brain in a glucocorticoid-dependent manner, leading to microglial activation and reduced neurogenesis.
Goto S, Kojima N, Komori M, Kawade N, Oshima K, Nadano D, Sasaki N, Horio F, Matsuda T, Miyata S. Goto S, et al. J Nutr Biochem. 2024 Jun;128:109608. doi: 10.1016/j.jnutbio.2024.109608. Epub 2024 Mar 6. J Nutr Biochem. 2024. PMID: 38458474
In the present study, we conducted RNA sequencing analysis and found that a short-term VitC deficiency altered the brain transcriptome in ODS rats, which cannot synthesize VitC. ...
In the present study, we conducted RNA sequencing analysis and found that a short-term VitC deficiency altered the brain transcriptom …
Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model.
Wu R, Williams C, Zhou J, Schlackow I, Emberson J, Reith C, Keech A, Robson J, Armitage J, Gray A, Simes J, Baigent C, Mihaylova B; CTT Collaboration secretariat; Armitage J, Baigent C, Barnes E, Blackwell L, Collins R, Davies K, Emberson J, Fulcher J, Halls H, Herrington WG, Holland L, Keech A, Kirby A, Mihaylova B, O'Connell R, Preiss D, Reith C, Simes J, Wilson K; CTT Collaboration trialists: A to Z trial (phase Z); Blazing M, Braunwald E, Lemos J, Murphy S, Pedersen TR, Pfeffer M, White H, Wiviott S; AFCAPS/TEXCAPS (AirForce/Texas Coronary Atherosclerosis Prevention Study); Clearfield M, Downs JR, Gotto A Jr, Weis S; ALERT (Assessment of Lescol in Renal Transplantation); Fellström B, Holdaas H, Jardine A, Pedersen TR; ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial); Gordon D, Davis B, Furberg C, Grimm R, Pressel S, Probstfield JL, Rahman M, Simpson L; ALLIANCE (Aggressive Lipid-Lowering Initiation Abates New Cardiac Events); Koren M; ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial); Dahlöf B, Gupta A, Poulter N, Sever P, Wedel H; ASPEN (Atorvastatin Study for the Prevention of Coronary Heart Disease Endpoints in Non-Insulin Dependent Diabe… See abstract for full author list ➔ Wu R, et al. Among authors: goto s. Br J Gen Pract. 2024 Feb 19;74(740):e189-98. doi: 10.3399/BJGP.2023.0198. Online ahead of print. Br J Gen Pract. 2024. PMID: 38373851 Free PMC article.
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD model is a novel resource for individualised long-term projections of health outcomes of CVD treatments....
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD mo …
Mass spectrometry-based proteomic analysis of proteins adsorbed by hexadecyl-immobilized cellulose bead column for the treatment of dialysis-related amyloidosis.
Yamamoto S, Yamamoto K, Hirao Y, Yamaguchi K, Nakajima K, Sato M, Kawachi M, Domon M, Goto K, Omori K, Iino N, Shimada H, Aoyagi R, Ei I, Goto S, Goto Y, Gejyo F, Yamamoto T, Narita I. Yamamoto S, et al. Among authors: goto s. Amyloid. 2024 Feb 11:1-11. doi: 10.1080/13506129.2024.2315148. Online ahead of print. Amyloid. 2024. PMID: 38343068
BACKGROUND: Dialysis-related amyloidosis (DRA) is a severe complication in end-stage kidney disease (ESKD) patients undergoing long-term dialysis treatment, characterized by the deposition of beta(2)-microglobulin-related amyloids (Abeta2M amyloid). ...
BACKGROUND: Dialysis-related amyloidosis (DRA) is a severe complication in end-stage kidney disease (ESKD) patients undergoing long-term …
Medical Record Survey after Comprehensive Health Checkup Referral and Its Contribution to the Early Detection of Cancer.
Yamanouchi Y, Senbonmatsu T, Yamaguchi T, Inoue I, Goto S, Soma T, Maruyama Y, Adachi M, Shinozuka N, Muramatsu T. Yamanouchi Y, et al. Among authors: goto s. J Pers Med. 2023 Dec 30;14(1):59. doi: 10.3390/jpm14010059. J Pers Med. 2023. PMID: 38248760 Free PMC article.
Early-stage cancers require a significantly longer time to establish a definitive diagnosis. In conclusion, short-term reports from the referring hospital are insufficient for a final diagnosis, and long-term follow-up is extremely important to increase the diagnosi …
Early-stage cancers require a significantly longer time to establish a definitive diagnosis. In conclusion, short-term reports from t …
Salvage robot-assisted radical prostatectomy after carbon ion radiotherapy to the prostate.
Shiota M, Tsukahara S, Takamatsu D, Tanegashima T, Ueda S, Blas L, Goto S, Kobayashi S, Matsumoto T, Inokuchi J, Shioyama Y, Eto M. Shiota M, et al. Among authors: goto s. Asian J Endosc Surg. 2024 Jan;17(1):e13279. doi: 10.1111/ases.13279. Asian J Endosc Surg. 2024. PMID: 38212264
CONCLUSIONS: This case series demonstrated the feasibility of salvage RARP after carbon ion radiotherapy. Although the urinary continence recovery was modest, short-term disease control was favorable....
CONCLUSIONS: This case series demonstrated the feasibility of salvage RARP after carbon ion radiotherapy. Although the urinary continence re …
Cerebellar injury in preterm infants less than 28 weeks gestational age.
Sasaki Y, Nemoto K, Goto S, Kato E. Sasaki Y, et al. Among authors: goto s. Pediatr Int. 2024 Jan-Dec;66(1):e15734. doi: 10.1111/ped.15734. Pediatr Int. 2024. PMID: 38156509

We performed a statistical analysis of the perinatal background and short-term morbidity of the two groups. RESULTS: Significant differences (p < 0.05) were observed between the groups with respect to the perinatal background, especially gestational weeks, birthweight,

…
We performed a statistical analysis of the perinatal background and short-term morbidity of the two groups. RESULTS: Significant diff …
Long-term follow-up of task-specific tremor after thalamotomy: a retrospective observational study.
Murakami M, Horisawa S, Kim K, Takeda N, Goto S, Kohara K, Kawamata T, Taira T. Murakami M, et al. Among authors: goto s. Ann Clin Transl Neurol. 2024 Feb;11(2):321-327. doi: 10.1002/acn3.51953. Epub 2023 Nov 29. Ann Clin Transl Neurol. 2024. PMID: 38018482 Free PMC article.
OBJECTIVE: This study aimed to report the long-term results of thalamotomy in 23 patients with task-specific tremor. ...INTERPRETATION: Thalamotomy significantly improves task-specific tremor with high long-term efficacy, and long-term follow-up is important …
OBJECTIVE: This study aimed to report the long-term results of thalamotomy in 23 patients with task-specific tremor. ...INTERPRETATIO …
Individual lifetime benefit from low-dose colchicine in patients with chronic coronary artery disease.
Burger PM, Dorresteijn JAN, Fiolet ATL, Koudstaal S, Eikelboom JW, Nidorf SM, Thompson PL, Cornel JH, Budgeon CA, Westendorp ICD, Beelen DPW, Martens FMAC, Steg PG, Asselbergs FW, Cramer MJ, Teraa M, Bhatt DL, Visseren FLJ, Mosterd A; LoDoCo2 Trial Investigators; UCC-SMART Study Group; REACH Registry Investigators. Burger PM, et al. Eur J Prev Cardiol. 2023 Dec 21;30(18):1950-1962. doi: 10.1093/eurjpc/zwad221. Eur J Prev Cardiol. 2023. PMID: 37409348
They may be expected to be of at least similar magnitude to those of intensified LDL-c and SBP reduction in a majority of patients already on conventional lipid-lowering and blood pressure-lowering therapy. The long-term benefits of treatment with low-dose colchicine were …
They may be expected to be of at least similar magnitude to those of intensified LDL-c and SBP reduction in a majority of patients already o …
185 results