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Diseases of the Coronary Microcirculation: Diagnosis and Treatment.
Ullrich-Daub H, Daub S, Olschewski M, Münzel T, Gori T. Ullrich-Daub H, et al. Among authors: gori t. Dtsch Arztebl Int. 2023 Nov 3;120(44):739-746. doi: 10.3238/arztebl.m2023.0205. Dtsch Arztebl Int. 2023. PMID: 37721132 Free PMC article. Review.
New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods....
New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to …
Coronary Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation: One-Year Outcomes of a Randomized Clinical Trial.
Desch S, Freund A, Akin I, Behnes M, Preusch MR, Zelniker TA, Skurk C, Landmesser U, Graf T, Eitel I, Fuernau G, Haake H, Nordbeck P, Hammer F, Felix SB, Hassager C, Kjærgaard J, Fichtlscherer S, Ledwoch J, Lenk K, Joner M, Steiner S, Liebetrau C, Voigt I, Zeymer U, Brand M, Schmitz R, Horstkotte J, Jacobshagen C, Pöss J, Abdel-Wahab M, Lurz P, Jobs A, de Waha S, Olbrich D, Sandig F, König IR, Brett S, Vens M, Klinge K, Thiele H; TOMAHAWK Investigators. Desch S, et al. JAMA Cardiol. 2023 Sep 1;8(9):827-834. doi: 10.1001/jamacardio.2023.2264. JAMA Cardiol. 2023. PMID: 37556123
IMPORTANCE: Myocardial infarction is a frequent cause of out-of-hospital cardiac arrest (OHCA). The long-term effect of early coronary angiography on patients with OHCA with possible coronary trigger but no ST-segment elevation remains unclear. ...
IMPORTANCE: Myocardial infarction is a frequent cause of out-of-hospital cardiac arrest (OHCA). The long-term effect of early coronar …
Sex-related differences in outcome after left atrial appendage occlusion: Insights from Europe and the EWOLUTION registry.
Paitazoglou C, Eitel I, Stiermaier T, Ince H, Kische S, Pokushalov E, Schmitz T, Schmidt B, Gori T, Meincke F, Vireca E, Wohlmuth P, Lucas B, Bergmann MW; EWOLUTION Investigators. Paitazoglou C, et al. Among authors: gori t. Catheter Cardiovasc Interv. 2023 Aug;102(2):283-292. doi: 10.1002/ccd.30759. Epub 2023 Jul 2. Catheter Cardiovasc Interv. 2023. PMID: 37393575
CONCLUSIONS: Females undergoing LAAO differ in various baseline variables, but after adjustment, we observed similar safety and efficacy of LAAO with no significant difference in long-term outcomes between women and men....
CONCLUSIONS: Females undergoing LAAO differ in various baseline variables, but after adjustment, we observed similar safety and efficacy of …
5-Year Outcomes After Bioresorbable Coronary Scaffolds Implanted With Improved Technique.
Stone GW, Kereiakes DJ, Gori T, Metzger DC, Stein B, Erickson M, Torzewski J, Kabour A, Piegari G, Cavendish J, Bertolet B, Stockelman KA, West NEJ, Ben-Yehuda O, Choi JW, Marx SO, Spertus JA, Ellis SG; ABSORB IV Investigators. Stone GW, et al. Among authors: gori t. J Am Coll Cardiol. 2023 Jul 18;82(3):183-195. doi: 10.1016/j.jacc.2023.05.003. Epub 2023 May 17. J Am Coll Cardiol. 2023. PMID: 37207924 Free article. Clinical Trial.
In the large-scale, blinded ABSORB IV trial, polymeric everolimus-eluting BVS implanted with improved technique demonstrated noninferior 1-year outcomes compared with cobalt chromium everolimus-eluting stents (CoCr-EES). OBJECTIVES: This study sought to evaluate the long-term
In the large-scale, blinded ABSORB IV trial, polymeric everolimus-eluting BVS implanted with improved technique demonstrated noninferior 1-y …
Six-months clinical and intracoronary imaging follow-up after reverse T and protrusion or double-kissing and crush stenting for the treatment of complex left main bifurcation lesions.
Abouelnour AE, Olschewski M, Makmur G, Ullrich H, Knorr M, Ahoopai M, Münzel T, Gori T. Abouelnour AE, et al. Among authors: gori t. Front Cardiovasc Med. 2023 Apr 27;10:1153652. doi: 10.3389/fcvm.2023.1153652. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37180808 Free PMC article.
Reverse T and Protrusion (rTAP) was shown to be a comparable strategy regarding short-term efficacy and safety, but with reduced procedural complexity. ...DKC by optical coherence tomography (OCT) on the intermediate term. METHODS: 52 consecutive patients with compl …
Reverse T and Protrusion (rTAP) was shown to be a comparable strategy regarding short-term efficacy and safety, but with reduced proc …
[Treat calcified stenoses correctly].
Blessing R, Gori T. Blessing R, et al. Among authors: gori t. Herz. 2022 Dec;47(6):503-512. doi: 10.1007/s00059-022-05144-4. Epub 2022 Nov 2. Herz. 2022. PMID: 36322196 Review. German.
Despite advances in technical possibilities and materials, the treatment of severely calcified stenoses continues to be associated with an increased periprocedural risk of complications and poor long-term clinical outcomes. The purpose of this article is to discuss the var …
Despite advances in technical possibilities and materials, the treatment of severely calcified stenoses continues to be associated with an i …
Restenosis after Coronary Stent Implantation: Cellular Mechanisms and Potential of Endothelial Progenitor Cells (A Short Guide for the Interventional Cardiologist).
Gori T. Gori T. Cells. 2022 Jun 30;11(13):2094. doi: 10.3390/cells11132094. Cells. 2022. PMID: 35805178 Free PMC article. Review.
Despite significant improvements in the biocompatibility of these devices throughout the last decades, they are prone, in as many as 10-20% of cases, to short- or long-term failure. In-stent restenosis is a multifactorial process with a complex and incompletely understood …
Despite significant improvements in the biocompatibility of these devices throughout the last decades, they are prone, in as many as 10-20% …
True Efficacy of LAA Closure: Patient Outcomes on Long-term Single-Antiplatelet or No Therapy: Insights From the EWOLUTION Registry.
Paitazoglou C, Bergmann MW, Ince H, Kische S, Romanov A, Schmitz T, Schmidt B, Gori T, Meincke F, Protopopov AV, Betts T, Vireca E, Wohlmuth P, Boersma L; theEWOLUTION Investigators. Paitazoglou C, et al. Among authors: gori t. J Invasive Cardiol. 2022 May;34(5):E348-E355. J Invasive Cardiol. 2022. PMID: 35501111 Free article.
BACKGROUND: Left atrial appendage occlusion (LAAO) is recommended for patients with atrial fibrillation at increased stroke risk, where effective long-term oral anticoagulation (OAC) is not feasible. In order to assess long-term safety of LAAO with aspirin monothera …
BACKGROUND: Left atrial appendage occlusion (LAAO) is recommended for patients with atrial fibrillation at increased stroke risk, where effe …
Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial.
Schnorbus B, Jurk K, Lackner KJ, Welk C, Münzel T, Gori T. Schnorbus B, et al. Among authors: gori t. Front Cardiovasc Med. 2021 Dec 13;8:780605. doi: 10.3389/fcvm.2021.780605. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34966798 Free PMC article.
The microvascular effect was however lost 1 day after stenting and during subsequent follow-up. Further studies are necessary to clarify the the long-term effects and potential benefits of P2Y12 inhibitors on microvascular damage. ...
The microvascular effect was however lost 1 day after stenting and during subsequent follow-up. Further studies are necessary to clarify the …
Rationale and design of the effects of EMpagliflozin on left ventricular DIAstolic function in diabetes (EmDia) study.
Jünger C, Prochaska JH, Gori T, Schulz A, Binder H, Daiber A, Koeck T, Rapp S, Lackner KJ, Münzel T, Wild PS. Jünger C, et al. Among authors: gori t. J Cardiovasc Med (Hagerstown). 2022 Mar 1;23(3):191-197. doi: 10.2459/JCM.0000000000001267. J Cardiovasc Med (Hagerstown). 2022. PMID: 34939776 Clinical Trial.
The reduction in cardiovascular mortality and hospitalization due to heart failure might be in part explained by the direct effects of empagliflozin on cardiac diastolic function. The EmDia trial investigates the short-term effects of empagliflozin compared to placebo on t …
The reduction in cardiovascular mortality and hospitalization due to heart failure might be in part explained by the direct effects of empag …
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