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Variation in Early Anakinra Use and Short-Term Outcomes in Multisystem Inflammatory Syndrome in Children.
Arthritis Rheumatol. 2023 Aug;75(8):1466-1476. doi: 10.1002/art.42495. Epub 2023 May 16.
Arthritis Rheumatol. 2023.
PMID: 36908050
CONCLUSION: We identified substantial variation in initial anakinra use in a real-world population of children with MIS-C, but no average short-term improvement in cardiovascular outcomes associated with early addition of anakinra to IVIG and/or glucocorticoids compared to …
CONCLUSION: We identified substantial variation in initial anakinra use in a real-world population of children with MIS-C, but no average sh …
Refining the Pediatric Multiple Organ Dysfunction Syndrome.
Weiss SL, Carcillo JA, Leclerc F, Leteurtre S, Schlapbach LJ, Tissieres P, Wynn JL, Lacroix J; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative.
Weiss SL, et al.
Pediatrics. 2022 Jan 1;149(1 Suppl 1):S13-S22. doi: 10.1542/peds.2021-052888C.
Pediatrics. 2022.
PMID: 34970671
Free PMC article.
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has been applied broadly to any patient with >1 concurrent organ dysfunction. However, the epidemiology, mechanisms, time course, and outcomes …
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has b …
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Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome.
LaRovere KL, Riggs BJ, Poussaint TY, Young CC, Newhams MM, Maamari M, Walker TC, Singh AR, Dapul H, Hobbs CV, McLaughlin GE, Son MBF, Maddux AB, Clouser KN, Rowan CM, McGuire JK, Fitzgerald JC, Gertz SJ, Shein SL, Munoz AC, Thomas NJ, Irby K, Levy ER, Staat MA, Tenforde MW, Feldstein LR, Halasa NB, Giuliano JS Jr, Hall MW, Kong M, Carroll CL, Schuster JE, Doymaz S, Loftis LL, Tarquinio KM, Babbitt CJ, Nofziger RA, Kleinman LC, Keenaghan MA, Cvijanovich NZ, Spinella PC, Hume JR, Wellnitz K, Mack EH, Michelson KN, Flori HR, Patel MM, Randolph AG; Overcoming COVID-19 Investigators.
LaRovere KL, et al. Among authors: giuliano js jr.
JAMA Neurol. 2021 May 1;78(5):536-547. doi: 10.1001/jamaneurol.2021.0504.
JAMA Neurol. 2021.
PMID: 33666649
Free PMC article.
A range of life-threatening and fatal neurologic conditions associated with COVID-19 infrequently occurred. Effects on long-term neurodevelopmental outcomes are unknown....
A range of life-threatening and fatal neurologic conditions associated with COVID-19 infrequently occurred. Effects on long-term neur …
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Ketamine Use for Tracheal Intubation in Critically Ill Children Is Associated With a Lower Occurrence of Adverse Hemodynamic Events.
Conway JA, Kharayat P, Sanders RC Jr, Nett S, Weiss SL, Edwards LR, Breuer R, Kirby A, Krawiec C, Page-Goertz C, Polikoff L, Turner DA, Shults J, Giuliano JS Jr, Orioles A, Balkandier S, Emeriaud G, Rehder KJ, Kian Boon JL, Shenoi A, Vanderford P, Nuthall G, Lee A, Zeqo J, Parsons SJ, Furlong-Dillard J, Meyer K, Harwayne-Gidansky I, Jung P, Adu-Darko M, Bysani GK, McCarthy MA, Shlomovich M, Toedt-Pingel I, Branca A, Esperanza MC, Al-Subu AM, Pinto M, Tallent S, Shetty R, Thyagarajan S, Ikeyama T, Tarquinio KM, Skippen P, Kasagi M, Howell JD, Nadkarni VM, Nishisaki A; National Emergency Airway Registry for Children (NEAR4KIDS) and for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI).
Conway JA, et al. Among authors: giuliano js jr.
Crit Care Med. 2020 Jun;48(6):e489-e497. doi: 10.1097/CCM.0000000000004314.
Crit Care Med. 2020.
PMID: 32317603
After adjusting for potential confounders and sites, ketamine use was associated with fewer hemodynamic tracheal intubation associated adverse events compared with other agents (adjusted odds ratio, 0.74; 95% CI, 0.58-0.95). The interaction term between ketamine use and in …
After adjusting for potential confounders and sites, ketamine use was associated with fewer hemodynamic tracheal intubation associated adver …
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Health-Related Quality of Life after Pediatric Severe Sepsis.
Syngal P, Giuliano JS Jr.
Syngal P, et al. Among authors: giuliano js jr.
Healthcare (Basel). 2018 Sep 11;6(3):113. doi: 10.3390/healthcare6030113.
Healthcare (Basel). 2018.
PMID: 30208619
Free PMC article.
Review.
Long-term outcomes and health-related quality of life (HRQL) following severe sepsis was defined as any outcome occurring after discharge from the hospital following an episode of severe sepsis which affected either the survivor or the survivor's family members. ...CONCLUS …
Long-term outcomes and health-related quality of life (HRQL) following severe sepsis was defined as any outcome occurring after disch …
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