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Selinexor in combination with weekly paclitaxel in patients with metastatic solid tumors: Results of an open label, single-center, multi-arm phase 1b study with expansion phase in ovarian cancer.
Westin SN, Fu S, Tsimberidou A, Piha-Paul S, Akhmedzhanov F, Yilmaz B, McQuinn L, Brink AL, Gong J, Leung CH, Lin H, Hong DS, Pant S, Carter B, Jazaeri A, Gershenson D, Sood AK, Coleman RL, Shah J, Meric-Bernstam F, Naing A. Westin SN, et al. Gynecol Oncol. 2023 Jan;168:76-82. doi: 10.1016/j.ygyno.2022.11.004. Epub 2022 Nov 21. Gynecol Oncol. 2023. PMID: 36423446 Free PMC article. Clinical Trial.
There were no DLTs and 60 mg was chosen as the RP2D due to long-term tolerability. Ninety-seven percent of patients had at least one treatment-emergent adverse event (TEAE), and the most common grade 3 TEAE were neutropenia (46%), anemia (31%), and nausea (21%). ...
There were no DLTs and 60 mg was chosen as the RP2D due to long-term tolerability. Ninety-seven percent of patients had at least one …
The Role of Oral Steroids in the Treatment of Phonotraumatic Vocal Fold Lesions in Women.
Amin MR, Achlatis S, Gherson S, Fang Y, Wang B, Born H, Branski RC, Johnson AM. Amin MR, et al. Otolaryngol Head Neck Surg. 2019 Mar;160(3):512-518. doi: 10.1177/0194599818804776. Epub 2018 Oct 16. Otolaryngol Head Neck Surg. 2019. PMID: 30322353 Free PMC article. Clinical Trial.
OBJECTIVES: (1) To determine the short-term effectiveness of oral steroids in women with benign vocal fold lesions and (2) to determine the effectiveness of adjuvant oral steroids in women undergoing voice therapy for benign vocal fold lesions. ...
OBJECTIVES: (1) To determine the short-term effectiveness of oral steroids in women with benign vocal fold lesions and (2) to determi …
Maternal BMI Associations with Maternal and Cord Blood Vitamin D Levels in a North American Subset of Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Participants.
Josefson JL, Reisetter A, Scholtens DM, Price HE, Metzger BE, Langman CB; HAPO Study Cooperative Research Group. Josefson JL, et al. PLoS One. 2016 Mar 4;11(3):e0150221. doi: 10.1371/journal.pone.0150221. eCollection 2016. PLoS One. 2016. PMID: 26942930 Free PMC article.
The objective of this study was to examine associations between maternal BMI and maternal and cord blood levels of 25-OHD in full term neonates born to a single racial cohort residing at similar latitude. ...
The objective of this study was to examine associations between maternal BMI and maternal and cord blood levels of 25-OHD in full term …