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Real-life experience with inotersen at CEPARM, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro.
Dias M, Pinto LF, Pinto MV, Gervais R, Accioli P, Amorim G, Guedes M, Gomes CP, Pedrosa RC, Waddington-Cruz M. Dias M, et al. Among authors: gervais r. Arq Neuropsiquiatr. 2024 Apr;82(4):1-7. doi: 10.1055/s-0044-1781463. Epub 2024 Apr 5. Arq Neuropsiquiatr. 2024. PMID: 38579737 Free PMC article.
Mutations in the transthyretin (TTR) gene cause the TTR protein to destabilize, misfold, aggregate, and deposit in body tissues, which makes ATTRv a disease with heterogeneous clinical phenotype. OBJECTIVE: To describe the long-term efficacy and safety of inotersen therapy …
Mutations in the transthyretin (TTR) gene cause the TTR protein to destabilize, misfold, aggregate, and deposit in body tissues, which makes …
Long-term effectiveness and treatment sequences in patients with extensive stage small cell lung cancer receiving atezolizumab plus chemotherapy: Results of the IFCT-1905 CLINATEZO real-world study.
Falchero L, Guisier F, Darrason M, Boyer A, Dayen C, Cousin S, Merle P, Lamy R, Madroszyk A, Otto J, Tomasini P, Assoun S, Canellas A, Gervais R, Hureaux J, Le Treut J, Leleu O, Naltet C, Tiercin M, Van Hulst S, Missy P, Morin F, Westeel V, Girard N. Falchero L, et al. Among authors: gervais r. Lung Cancer. 2023 Nov;185:107379. doi: 10.1016/j.lungcan.2023.107379. Epub 2023 Sep 22. Lung Cancer. 2023. PMID: 37757576 Free article.
CPAP telemonitoring can track Cheyne-Stokes respiration and detect serious cardiac events: The AlertApnée Study.
Prigent A, Pellen C, Texereau J, Bailly S, Coquerel N, Gervais R, Liegaux JM, Luraine R, Renaud JC, Serandour AL, Pépin JL. Prigent A, et al. Among authors: gervais r. Respirology. 2022 Feb;27(2):161-169. doi: 10.1111/resp.14192. Epub 2021 Dec 6. Respirology. 2022. PMID: 34873795 Free article.
BACKGROUND AND OBJECTIVE: Case reports have suggested that continuous positive airway pressure (CPAP) telemonitoring can detect the onset of acute cardiac events such as decompensated heart failure (HF) or atrial fibrillation through an increase in the apnoea-hypopnoea index (AHI …
BACKGROUND AND OBJECTIVE: Case reports have suggested that continuous positive airway pressure (CPAP) telemonitoring can detect the onset of …
Treatment strategies for unresectable locally advanced non-small cell lung cancer in the real-life ESME cohort.
Girard N, Perol M, Simon G, Audigier Valette C, Gervais R, Debieuvre D, Schott R, Quantin X, Coudert B, Lena H, Carton M, Robain M, Filleron T, Chouaid C. Girard N, et al. Among authors: gervais r. Lung Cancer. 2021 Dec;162:119-127. doi: 10.1016/j.lungcan.2021.10.017. Epub 2021 Nov 6. Lung Cancer. 2021. PMID: 34775215
Clinical outcomes are actually higher than those reported in landmark clinical trials, which suggests that an optimized and individualized selection of patients allows for prolonged survival. Long-term outcomes are similar after sequential or concurrent chemoradiotherapy.. …
Clinical outcomes are actually higher than those reported in landmark clinical trials, which suggests that an optimized and individualized s …
First-line pembrolizumab with or without platinum doublet chemotherapy in non-small-cell lung cancer patients with PD-L1 expression ≥50.
Descourt R, Chouaid C, Pérol M, Besse B, Greillier L, Bylicki O, Ricordel C, Guisier F, Gervais R, Schott R, Auliac JB, Robinet G, Decroisette C. Descourt R, et al. Among authors: gervais r. Future Oncol. 2021 Aug;17(23):3007-3016. doi: 10.2217/fon-2020-1202. Epub 2021 Jun 22. Future Oncol. 2021. PMID: 34156285
The study will allow a direct comparison of the proportion of patients who derive long-term benefit from the treatment. Clinical trial number: EudraCT (2020-002626-86); ClinicalTrials.gov (NCT04547504). ...
The study will allow a direct comparison of the proportion of patients who derive long-term benefit from the treatment. Clinical tria …
Five Year Survival Update From KEYNOTE-010: Pembrolizumab Versus Docetaxel for Previously Treated, Programmed Death-Ligand 1-Positive Advanced NSCLC.
Herbst RS, Garon EB, Kim DW, Cho BC, Gervais R, Perez-Gracia JL, Han JY, Majem M, Forster MD, Monnet I, Novello S, Gubens MA, Boyer M, Su WC, Samkari A, Jensen EH, Kobie J, Piperdi B, Baas P. Herbst RS, et al. Among authors: gervais r. J Thorac Oncol. 2021 Oct;16(10):1718-1732. doi: 10.1016/j.jtho.2021.05.001. Epub 2021 May 26. J Thorac Oncol. 2021. PMID: 34048946 Free article. Clinical Trial.
Exploratory biomarker analysis revealed that higher tissue tumor mutational burden (175 mutations per exome) was associated with improved outcomes with pembrolizumab. CONCLUSIONS: Pembrolizumab continued to provide long-term benefit than docetaxel in patients with previous …
Exploratory biomarker analysis revealed that higher tissue tumor mutational burden (175 mutations per exome) was associated with improved ou …
Impact of anxio-depressive symptoms and cognitive function on oral anticancer therapies adherence.
Dos Santos M, Lange M, Gervais R, Clarisse B, Capel A, Barillet M, Grellard JM, Heutte N, Licaj I, Joly F. Dos Santos M, et al. Among authors: gervais r. Support Care Cancer. 2019 Sep;27(9):3573-3581. doi: 10.1007/s00520-019-4644-4. Epub 2019 Jan 28. Support Care Cancer. 2019. PMID: 30690685
Non-adherence was associated with lower working memory (P = 0.037) and digit memory (P = 0.018) at M1 and short-term memory (P = 0.04) at M3. Patients with more than eight co-medications were more often non-adherents (P = 0.055). ...Focusing on depressive symptoms before i …
Non-adherence was associated with lower working memory (P = 0.037) and digit memory (P = 0.018) at M1 and short-term memory (P = 0.04 …
Induction or consolidation chemotherapy for unresectable stage III non-small-cell lung cancer patients treated with concurrent chemoradiation: a randomised phase II trial GFPC - IFCT 02-01.
Fournel P, Vergnenégre A, Robinet G, Léna H, Gervais R, Le Caer H, Souquet PJ, Chavaillon JM, Bozonnat MC, Daurès JP, Chouaid C, Martel-Lafay I; GFPC and IFCT Team. Fournel P, et al. Among authors: gervais r. Eur J Cancer. 2016 Jan;52:181-7. doi: 10.1016/j.ejca.2015.10.072. Epub 2015 Dec 12. Eur J Cancer. 2016. PMID: 26689864 Clinical Trial.
Response rates were similar in both arms with a trend in favour for consolidation arm for long-term survival....
Response rates were similar in both arms with a trend in favour for consolidation arm for long-term survival....
Does bilobectomy offer satisfactory long-term survival outcome for non-small cell lung cancer?
Icard P, Heyndrickx M, Galateau-Sallé F, Rosat P, Lerochais JP, Gervais R, Zalcman G, Hanouz JL. Icard P, et al. Among authors: gervais r. Ann Thorac Surg. 2013 May;95(5):1726-33. doi: 10.1016/j.athoracsur.2013.01.071. Epub 2013 Apr 2. Ann Thorac Surg. 2013. PMID: 23561806
Analysis aimed at determining perioperative mortality and morbidity, and at studying prognostic factors for long-term survival using the 7th TNM classification. RESULTS: A total of 103 patients (85 males; mean age 62 years) underwent upper-middle bilobectomy (n = 54) or lo …
Analysis aimed at determining perioperative mortality and morbidity, and at studying prognostic factors for long-term survival using …
Sites of left and right ventricular lead implantation and response to cardiac resynchronization therapy observations from the REVERSE trial.
Thébault C, Donal E, Meunier C, Gervais R, Gerritse B, Gold MR, Abraham WT, Linde C, Daubert JC; REVERSE study group. Thébault C, et al. Among authors: gervais r. Eur Heart J. 2012 Nov;33(21):2662-71. doi: 10.1093/eurheartj/ehr505. Epub 2012 Jan 26. Eur Heart J. 2012. PMID: 22285578 Clinical Trial.
CONCLUSIONS: A more favourable outcome of CRT with regard to LV reverse remodelling and the composite of time to death or first HF hospitalization was observed when the LV lead tip was implanted in the lateral wall, away from the apex, while the position of the RV lead tip was in …
CONCLUSIONS: A more favourable outcome of CRT with regard to LV reverse remodelling and the composite of time to death or first HF hospitali …
21 results