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Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.
Am J Respir Crit Care Med. 2012 Mar 15;185(6):645-52. doi: 10.1164/rccm.201109-1666OC. Epub 2011 Dec 28.
Am J Respir Crit Care Med. 2012.
PMID: 22198974
Clinical Trial.
RATIONALE: New treatment strategies are needed to improve airway clearance and reduce the morbidity and the time burden associated with cystic fibrosis (CF). OBJECTIVES: To determine whether long-term treatment with inhaled mannitol, an osmotic agent, improves lung functio …
RATIONALE: New treatment strategies are needed to improve airway clearance and reduce the morbidity and the time burden associated with cyst …
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group.
Geller DE, Eigen H, Fiel SB, Clark A, Lamarre AP, Johnson CA, Konstan MW.
Geller DE, et al.
Pediatr Pulmonol. 1998 Feb;25(2):83-7. doi: 10.1002/(sici)1099-0496(199802)25:2<83::aid-ppul2>3.0.co;2-o.
Pediatr Pulmonol. 1998.
PMID: 9516090
Clinical Trial.
There was a trend (P = 0.06) toward greater improvement in forced expiratory flow in 1 s in the SS/MA group (4.3%) compared with the HT/PA group (2.5%). These results indicate that the short-term spirometric response to dornase alfa is influenced in part by the physical ch …
There was a trend (P = 0.06) toward greater improvement in forced expiratory flow in 1 s in the SS/MA group (4.3%) compared with the HT/PA g …
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