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The role of extreme phenotype selection studies in the identification of clinically relevant genotypes in cancer research.
Perez-Gracia JL, Gloria Ruiz-Ilundain M, Garcia-Ribas I, Maria Carrasco E. Perez-Gracia JL, et al. Among authors: garcia ribas i. Cancer. 2002 Oct 1;95(7):1605-10. doi: 10.1002/cncr.10877. Cancer. 2002. PMID: 12237932 Free article.
The study of individuals with phenotypes that imply an extremely good prognosis, such as long-term survivors of theoretically incurable malignancies or individuals who seem to be protected against a certain neoplastic disorder despite having a markedly increased risk for i …
The study of individuals with phenotypes that imply an extremely good prognosis, such as long-term survivors of theoretically incurab …
A family of bicistronic vectors to enhance both local and systemic antitumor effects of HSVtk or cytokine expression in a murine melanoma model.
Castleden SA, Chong H, Garcia-Ribas I, Melcher AA, Hutchinson G, Roberts B, Hart IR, Vile RG. Castleden SA, et al. Among authors: garcia ribas i. Hum Gene Ther. 1997 Nov 20;8(17):2087-102. doi: 10.1089/hum.1997.8.17-2087. Hum Gene Ther. 1997. PMID: 9414257
In a tumor-prevention model, HSVtk killing, in an environment preprimed with GM-CSF, generated the best long-term immune protection. However, in a short-term therapy model, continued IL-2 expression was most effective against 3-day established tumors. This probably …
In a tumor-prevention model, HSVtk killing, in an environment preprimed with GM-CSF, generated the best long-term immune protection. …