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Gym lifestyle factors and male reproductive health: a study into young adult usage and perceptions.
Newman-Sanders A, Kirkman-Brown JC, Gallagher MT. Newman-Sanders A, et al. Among authors: gallagher mt. Reprod Biomed Online. 2024 Jan;48(1):103623. doi: 10.1016/j.rbmo.2023.103623. Epub 2023 Oct 18. Reprod Biomed Online. 2024. PMID: 38029492 Free article.

Men were more likely to make a change in their behaviour if it had a long-term compared with a short-term effect on their fertility (P < 10(-5)). ...Men have a potentially alarming lack of concern over their own fertility and how factors such as gym supplements c

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Men were more likely to make a change in their behaviour if it had a long-term compared with a short-term effect on their fert …
Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.
Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H; DUPRO Steering Committee and DUPLEX Investigators. Rheault MN, et al. N Engl J Med. 2023 Dec 28;389(26):2436-2445. doi: 10.1056/NEJMoa2308550. Epub 2023 Nov 3. N Engl J Med. 2023. PMID: 37921461 Clinical Trial.
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The efficacy and safety of longer-term treatment with sparsentan for FSGS are unknown. METHODS: In this phase 3 trial, we enrolled patient …
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The e …
Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.
Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V; PROTECT Investigators. Heerspink HJL, et al. Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1. Lancet. 2023. PMID: 37015244 Clinical Trial.
Future analyses after completion of the 2-year double-blind period will show whether these beneficial effects translate into a long-term nephroprotective potential of sparsentan. FUNDING: Travere Therapeutics....
Future analyses after completion of the 2-year double-blind period will show whether these beneficial effects translate into a long-term …
mGluR-dependent plasticity in rodent models of Alzheimer's disease.
Valdivia G, Ardiles AO, Idowu A, Salazar C, Lee HK, Gallagher M, Palacios AG, Kirkwood A. Valdivia G, et al. Among authors: gallagher m. Front Synaptic Neurosci. 2023 Mar 2;15:1123294. doi: 10.3389/fnsyn.2023.1123294. eCollection 2023. Front Synaptic Neurosci. 2023. PMID: 36937569 Free PMC article.
Long-term potentiation (LTP) and depression (LTD) are currently the most comprehensive models of synaptic plasticity models to subserve learning and memory. ...
Long-term potentiation (LTP) and depression (LTD) are currently the most comprehensive models of synaptic plasticity models to subser …
Ex vivo expansion of circulating tumour cells (CTCs).
Mohamed BM, Ward MP, Bates M, Spillane CD, Kelly T, Martin C, Gallagher M, Heffernan S, Norris L, Kennedy J, Saadeh FA, Gleeson N, Brooks DA, Brooks RD, Selemidis S, O'Toole S, O'Leary JJ. Mohamed BM, et al. Among authors: gallagher m. Sci Rep. 2023 Mar 6;13(1):3704. doi: 10.1038/s41598-023-30733-6. Sci Rep. 2023. PMID: 36879003 Free PMC article.
The presence of CTC clusters was required to establish and maintain long-term cultures. This novel methodology for the long-term culture of CTCs will aid in the development of downstream applications, including CTC theranostics....
The presence of CTC clusters was required to establish and maintain long-term cultures. This novel methodology for the long-term …
Epilepsy with anterior temporal encephaloceles: Baseline characteristics, post-surgical outcomes, and comparison to mesial temporal sclerosis.
Samudra N, Armour E, Gonzalez H, Mattingly D, Haas K, Singh P, Sonmezturk H, Gallagher M, Crudele A, Nobis W, Reddy S, Jacobs M, Aulino JM, Bick S, Morgan V, Englot D, Abou-Khalil B. Samudra N, et al. Among authors: gallagher m. Epilepsy Behav. 2023 Feb;139:109061. doi: 10.1016/j.yebeh.2022.109061. Epub 2022 Dec 30. Epilepsy Behav. 2023. PMID: 36587487
Most patients had limited temporal cortical resections sparing mesial structures. Of the twenty ATE patients who had a long-term postsurgical follow-up, seventeen (85%) had International League Against Epilepsy (ILAE) Class 1 or 2 outcomes. ...
Most patients had limited temporal cortical resections sparing mesial structures. Of the twenty ATE patients who had a long-term post …
Treatment decision-making and care among older adults with kidney failure: protocol for a multicentre, prospective observational cohort study with nested substudies and linked qualitative research (the Elderly Advanced CKD Programme).
Siriwardana A, Gray NA, Makris A, Li CK, Yong K, Mehta Y, Ramos J, Di Tanna GL, Gianacas C, Addo IY, Roxburgh S, Naganathan V, Foote C, Gallagher M. Siriwardana A, et al. Among authors: gallagher m. BMJ Open. 2022 Dec 29;12(12):e066156. doi: 10.1136/bmjopen-2022-066156. BMJ Open. 2022. PMID: 36581411 Free PMC article.
Patients will be prospectively followed until death or a maximum of 4 years, with the primary outcome being survival. Secondary outcomes are receipt of short-term acute dialysis, receipt of long-term maintenance dialysis, changes in biochemistry and end-of-life care …
Patients will be prospectively followed until death or a maximum of 4 years, with the primary outcome being survival. Secondary outcomes are …
Comparing survival in patients with chronic kidney disease across three countries - Results from the study of heart and renal protection-extended review.
Talbot B, Cass A, Walker R, Hooi L, Jardine M, Jun M, Rogers K, Sukkar L, Smyth B, Gallagher M. Talbot B, et al. Among authors: gallagher m. Nephrology (Carlton). 2023 Jan;28(1):36-43. doi: 10.1111/nep.14127. Epub 2022 Nov 9. Nephrology (Carlton). 2023. PMID: 36309984 Free PMC article. Clinical Trial.
CONCLUSION: This study allows a better understanding of the differences in long-term mortality risk across participants from AUS, MYL, and NZ in extended follow-up of the SHARP study and demonstrates the feasibility and value of extended follow-up of participants enrolled …
CONCLUSION: This study allows a better understanding of the differences in long-term mortality risk across participants from AUS, MYL …
Heterogeneity of the long-term economic burden of severe sickle cell disease: a 5-year longitudinal analysis.
Gallagher ME, Chawla A, Brady BL, Badawy SM. Gallagher ME, et al. J Med Econ. 2022 Jan-Dec;25(1):1140-1148. doi: 10.1080/13696998.2022.2133824. J Med Econ. 2022. PMID: 36222016 Free article.
BACKGROUND: Sickle cell disease (SCD) is a lifelong burdensome disorder of heterogenic expression. This study investigated the longer-term economic burden of severe presentation of SCD. As SCD treatment landscapes evolve toward curative intent gene therapies, understanding …
BACKGROUND: Sickle cell disease (SCD) is a lifelong burdensome disorder of heterogenic expression. This study investigated the longer-ter …
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning.
Nickbakhsh S, Hughes J, Christofidis N, Griffiths E, Shaaban S, Enright J, Smollett K, Nomikou K, Palmalux N, Tong L, Carmichael S, Sreenu VB, Orton R, Goldstein EJ, Tomb RM; COVID-19 Genomics UK (COG-UK) Consortium; Templeton K, Gunson RN, da Silva Filipe A, Milosevic C, Thomson E, Robertson DL, Holden MTG, Illingworth CJR, Smith-Palmer A. Nickbakhsh S, et al. Sci Rep. 2022 Jul 19;12(1):11735. doi: 10.1038/s41598-022-15661-1. Sci Rep. 2022. PMID: 35853960 Free PMC article.
One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of term, close living conditions within residential halls, and high social contact rates. ...The impact of student infections on the local …
One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of …
126 results