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2008 2
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Page 1
Ataluren delays loss of ambulation and respiratory decline in nonsense mutation Duchenne muscular dystrophy patients.
McDonald CM, Muntoni F, Penematsa V, Jiang J, Kristensen A, Bibbiani F, Goodwin E, Gordish-Dressman H, Morgenroth L, Werner C, Li J, Able R, Trifillis P, Tulinius M; Study 019 investigators. McDonald CM, et al. J Comp Eff Res. 2022 Feb;11(3):139-155. doi: 10.2217/cer-2021-0196. Epub 2021 Nov 18. J Comp Eff Res. 2022. PMID: 34791888 Free PMC article. Clinical Trial.
Aim: We investigated the effect of ataluren plus standard of care (SoC) on age at loss of ambulation (LoA) and respiratory decline in patients with nonsense mutation Duchenne muscular dystrophy (nmDMD) versus patients with DMD on SoC alone. Patients & methods: Study 019 was a …
Aim: We investigated the effect of ataluren plus standard of care (SoC) on age at loss of ambulation (LoA) and respiratory decline in patien …
aPKC-Mediated Persistent Increase in AMPA/NMDA Ratio in the VTA Participates in the Neuroadaptive Signal Necessary to Induce NAc Synaptic Plasticity After Cocaine Administration.
Vaquer-Alicea ADC, Vázquez-Torres R, Devarie-Hornedo M, Vicenty-Padilla JC, Santos-Vera B, María-Ríos C, Vélez-Hernández ME, Sacktor T, Jiménez-Rivera CA. Vaquer-Alicea ADC, et al. Neuroscience. 2018 Nov 10;392:129-140. doi: 10.1016/j.neuroscience.2018.09.011. Epub 2018 Sep 21. Neuroscience. 2018. PMID: 30243909 Free PMC article.
Association between maternal diet factors and hemoglobin levels, glucose tolerance, blood pressure and gestational age in a Hispanic population.
Soto R, Guilloty N, Anzalota L, Rosario Z, Cordero JF, Palacios C. Soto R, et al. Arch Latinoam Nutr. 2015 Jun;65(2):86-96. Arch Latinoam Nutr. 2015. PMID: 26817380 Free PMC article.
A total of 180 participants completed the FFQ; low hemoglobin levels was found in 19.2%, high blood glucose levels was found in 21.1% by fasting blood glucose test and 24.6%by 1-hour 50 g oral glucose screening test, high blood pressure was found in 2.9% (systolic) and 6.5% (dias …
A total of 180 participants completed the FFQ; low hemoglobin levels was found in 19.2%, high blood glucose levels was found in 21.1% by fas …
Diet, Pre-pregnancy BMI, and Gestational Weight Gain in Puerto Rican Women.
Guilloty NI, Soto R, Anzalota L, Rosario Z, Cordero JF, Palacios C. Guilloty NI, et al. Matern Child Health J. 2015 Nov;19(11):2453-61. doi: 10.1007/s10995-015-1764-4. Matern Child Health J. 2015. PMID: 26100133 Free PMC article.
METHODS: This is a secondary analysis of a longitudinal cohort study of pregnant women exploring the risk factors for preterm birth, the Puerto Rico Testsite for Exploring Contamination Threats program. ...Analysis of associations between variables was conducted using Chi …
METHODS: This is a secondary analysis of a longitudinal cohort study of pregnant women exploring the risk factors for preterm birth, …
Tamoxifen and estradiol improved locomotor function and increased spared tissue in rats after spinal cord injury: their antioxidant effect and role of estrogen receptor alpha.
Mosquera L, Colón JM, Santiago JM, Torrado AI, Meléndez M, Segarra AC, Rodríguez-Orengo JF, Miranda JD. Mosquera L, et al. Brain Res. 2014 May 2;1561:11-22. doi: 10.1016/j.brainres.2014.03.002. Epub 2014 Mar 15. Brain Res. 2014. PMID: 24637260 Free PMC article.
We also observed that ER-alpha was up-regulated after SCI. Long-term treatment (28 DPI) with estradiol and Tamoxifen reduced the extent of the lesion cavity, an effect also mediated by ER-alpha. ...Tamoxifens effects during late stages of SCI support the use of this drug a …
We also observed that ER-alpha was up-regulated after SCI. Long-term treatment (28 DPI) with estradiol and Tamoxifen reduced the exte …
Oral HPV infection in a clinic-based sample of Hispanic men.
Colon-López V, Quiñones-Avila V, Del Toro-Mejías LM, Reyes K, Rivera ME, Nieves K, Sánchez-Vazquez MM, Martínez-Ferrer M, Ortiz AP. Colon-López V, et al. BMC Oral Health. 2014 Jan 24;14:7. doi: 10.1186/1472-6831-14-7. BMC Oral Health. 2014. PMID: 24460642 Free PMC article.
Interventions in STI clinics should include screening for HPV in the oral cavity for the early detection and reduction of long-term consequences of oral HPV infection, such as oropharyngeal cancer....
Interventions in STI clinics should include screening for HPV in the oral cavity for the early detection and reduction of long-term c …
The cooperative international neuromuscular research group Duchenne natural history study: glucocorticoid treatment preserves clinically meaningful functional milestones and reduces rate of disease progression as measured by manual muscle testing and other commonly used clinical trial outcome measures.
Henricson EK, Abresch RT, Cnaan A, Hu F, Duong T, Arrieta A, Han J, Escolar DM, Florence JM, Clemens PR, Hoffman EP, McDonald CM; CINRG Investigators. Henricson EK, et al. Muscle Nerve. 2013 Jul;48(1):55-67. doi: 10.1002/mus.23808. Epub 2013 May 6. Muscle Nerve. 2013. PMID: 23649481 Free PMC article.
The linearity and magnitude of decline in measures were affected by maturational changes and functional status. CONCLUSIONS: In DMD, long-term use of GCs showed reduced strength loss and preserved functional capabilities and PFTs compared with previous natural history stud …
The linearity and magnitude of decline in measures were affected by maturational changes and functional status. CONCLUSIONS: In DMD, long- …
Soluble and cell-associated insulin receptor dysfunction correlates with severity of HAND in HIV-infected women.
Gerena Y, Skolasky RL, Velez JM, Toro-Nieves D, Mayo R, Nath A, Wojna V. Gerena Y, et al. PLoS One. 2012;7(5):e37358. doi: 10.1371/journal.pone.0037358. Epub 2012 May 22. PLoS One. 2012. PMID: 22629383 Free PMC article.
These abnormalities may occur as a result of chronic HIV infection, long-term use of combined antiretroviral treatment (CART), aging, genetic predisposition, or a combination of these factors, and may increase morbidity and mortality in this population. ...
These abnormalities may occur as a result of chronic HIV infection, long-term use of combined antiretroviral treatment (CART), aging, …
Anaerobic power and muscle strength in human immunodeficiency virus-positive preadolescents.
Ramos E, Guttierrez-Teissoonniere S, Conde JG, Baez-Cordova JA, Guzman-Villar B, Lopategui-Corsino E, Frontera WR. Ramos E, et al. PM R. 2012 Mar;4(3):171-5. doi: 10.1016/j.pmrj.2011.11.009. Epub 2012 Feb 23. PM R. 2012. PMID: 22364955 Free PMC article.
Our findings of impaired anaerobic capacity can have clinical implications in this population because most of the activities of daily living, such as play, leisure, and sport activities, are short term and high intensity (anaerobic) in nature....
Our findings of impaired anaerobic capacity can have clinical implications in this population because most of the activities of daily living …
Schedule Dependence in Cancer Therapy: Intravenous Vitamin C and the Systemic Saturation Hypothesis.
Gonzalez MJ, Miranda Massari JR, Duconge J, Riordan NH, Ichim T. Gonzalez MJ, et al. J Orthomol Med. 2012 Jan 1;27(1):9-12. J Orthomol Med. 2012. PMID: 24860238 Free PMC article.
Practitioners should pay more attention to the cumulative vitamin C effect instead of the vitamin C concentrations to account for observed discrepancy in antitumor response. We suggest that multiple, intermittent, short-term intravenous infusions of vitamin C over a longer …
Practitioners should pay more attention to the cumulative vitamin C effect instead of the vitamin C concentrations to account for observed d …
16 results