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Long-term effect of azithromycin in bronchiolitis obliterans syndrome.
Gan CT, Ward C, Meachery G, Lordan JL, Fisher AJ, Corris PA. Gan CT, et al. BMJ Open Respir Res. 2019 Oct 15;6(1):e000465. doi: 10.1136/bmjresp-2019-000465. eCollection 2019. BMJ Open Respir Res. 2019. PMID: 31673366 Free PMC article. Clinical Trial.
Survival of patients with early BOS was similar to late-onset BOS (log-rank test p=0.74). DISCUSSION: Long-term treatment with azithromycin slows down the progression of BOS, although the effect of TLI may affect the observed attenuation of FEV(1) decline. BOS progression …
Survival of patients with early BOS was similar to late-onset BOS (log-rank test p=0.74). DISCUSSION: Long-term treatment with azithr …
Non-cystic fibrosis bronchiectasis.
McDonnell MJ, Ward C, Lordan JL, Rutherford RM. McDonnell MJ, et al. QJM. 2013 Aug;106(8):709-15. doi: 10.1093/qjmed/hct109. Epub 2013 May 30. QJM. 2013. PMID: 23728208 Review.
The associated burden of disease in terms of increased morbidity, reduced quality of life and the socioeconomic cost of long-term management is significant. Further research is essential to improve our understanding of the development and progression of this disease. ...
The associated burden of disease in terms of increased morbidity, reduced quality of life and the socioeconomic cost of long-term man …
From gastric aspiration to airway inflammation.
Brownlee IA, Aseeri A, Ward C, Pearson JP. Brownlee IA, et al. Monaldi Arch Chest Dis. 2010 Jun;73(2):54-63. doi: 10.4081/monaldi.2010.299. Monaldi Arch Chest Dis. 2010. PMID: 20957772 Review.
A range of physiological factors govern both occurrence of gastric reflux into the pharynx/larynx and could also increase the susceptibility of certain individuals to disease progression. A range of long-term surgical and pharmacological intervention studies are necessary …
A range of physiological factors govern both occurrence of gastric reflux into the pharynx/larynx and could also increase the susceptibility …
A call for standardization of antireflux surgery in the lung transplantation population.
Robertson AG, Shenfine J, Ward C, Pearson JP, Dark JH, Corris PA, Griffin SM. Robertson AG, et al. Transplantation. 2009 Apr 27;87(8):1112-4. doi: 10.1097/TP.0b013e31819f7010. Transplantation. 2009. PMID: 19384154 Review.
Long-term survival post lung transplant is reduced significantly by Bronchiolitis Obliterans Syndrome. ...
Long-term survival post lung transplant is reduced significantly by Bronchiolitis Obliterans Syndrome. ...
Pepsin, a biomarker of gastric aspiration in lung allografts: a putative association with rejection.
Stovold R, Forrest IA, Corris PA, Murphy DM, Smith JA, Decalmer S, Johnson GE, Dark JH, Pearson JP, Ward C. Stovold R, et al. Am J Respir Crit Care Med. 2007 Jun 15;175(12):1298-303. doi: 10.1164/rccm.200610-1485OC. Epub 2007 Apr 5. Am J Respir Crit Care Med. 2007. PMID: 17413126
RATIONALE: Human lung transplantation is a therapeutic option for selected patients with advanced cardiopulmonary disease, but long-term survival is limited by chronic rejection. Persistent acute rejection and gastric aspiration have been implicated as risk factors but the …
RATIONALE: Human lung transplantation is a therapeutic option for selected patients with advanced cardiopulmonary disease, but long-term …