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The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.
Dos Remedios CG, Lal SP, Li A, McNamara J, Keogh A, Macdonald PS, Cooke R, Ehler E, Knöll R, Marston SB, Stelzer J, Granzier H, Bezzina C, van Dijk S, De Man F, Stienen GJM, Odeberg J, Pontén F, Linke WA, Linke W, van der Velden J. Dos Remedios CG, et al. Biophys Rev. 2017 Aug;9(4):431-441. doi: 10.1007/s12551-017-0305-3. Epub 2017 Aug 14. Biophys Rev. 2017. PMID: 28808947 Free PMC article. Review.
The tissues most commonly requested are from donor left ventricles, but right ventricles, atria, interventricular system, and coronary arteries vessels have also been reported. All tissues are stored for long-term use in liquid N or vapor (170-180 C), and are shipped under …
The tissues most commonly requested are from donor left ventricles, but right ventricles, atria, interventricular system, and coronary arter …
Stabilised beta-catenin in postnatal ventricular myocardium leads to dilated cardiomyopathy and premature death.
Hirschy A, Croquelois A, Perriard E, Schoenauer R, Agarkova I, Hoerstrup SP, Taketo MM, Pedrazzini T, Perriard JC, Ehler E. Hirschy A, et al. Basic Res Cardiol. 2010 Sep;105(5):597-608. doi: 10.1007/s00395-010-0101-8. Epub 2010 Apr 8. Basic Res Cardiol. 2010. PMID: 20376467 Free article.
Beta-catenin is a component of the intercalated disc in cardiomyocytes, but can also be involved in signalling and activation of gene transcription. We wanted to determine how long-term changes in beta-catenin expression levels would affect mature cardiomyocytes. ...A deta …
Beta-catenin is a component of the intercalated disc in cardiomyocytes, but can also be involved in signalling and activation of gene transc …