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LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.
Lancet. 2022 Nov 26;400(10366):1869-1881. doi: 10.1016/S0140-6736(22)02033-5. Epub 2022 Oct 27.
Lancet. 2022.
PMID: 36354040
Clinical Trial.
BACKGROUND: Treating hyperglycaemia and obesity in individuals with type 2 diabetes using multi-receptor agonists can improve short-term and long-term outcomes. LY3437943 is a single peptide with agonist activity for glucagon, glucose-dependent insulinotropic polype …
BACKGROUND: Treating hyperglycaemia and obesity in individuals with type 2 diabetes using multi-receptor agonists can improve short-term …
Effects of teriparatide in Chinese and Caucasian women with osteoporosis: bridging study on efficacy.
Xie Z, Chen Y, Gurbuz S, Zhang B, Li Y, Bai F, Chen Y.
Xie Z, et al. Among authors: gurbuz s.
Clin Interv Aging. 2019 May 27;14:959-968. doi: 10.2147/CIA.S181929. eCollection 2019.
Clin Interv Aging. 2019.
PMID: 31213783
Free PMC article.
Clinical Trial.
OBJECTIVE: To bridge the efficacy and compare the safety of the 24-week teriparatide treatment in a Chinese osteoporosis study (NCT00414973) to a large international trial (FPT, NCT00670501) to determine whether long-term results from the international study were applicabl …
OBJECTIVE: To bridge the efficacy and compare the safety of the 24-week teriparatide treatment in a Chinese osteoporosis study (NCT00414973) …
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Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis: Subgroup analysis of Latin American patients in the phase 3 randomized UNCOVER-3 study.
Valenzuela F, de la Cruz Fernandez C, Galimberti RL, Gürbüz S, McKean-Matthews M, Goncalves L, Romiti R.
Valenzuela F, et al. Among authors: gurbuz s.
Actas Dermosifiliogr. 2017 Jul-Aug;108(6):550-563. doi: 10.1016/j.ad.2017.02.005. Epub 2017 Mar 23.
Actas Dermosifiliogr. 2017.
PMID: 28342534
Free article.
Clinical Trial.
English, Spanish.
At week 12, patients maintaining efficacy response and adequate overall safety were assigned, at the discretion of the investigator, to long-term extension with ixekizumab Q4W. RESULTS: At week 12, Psoriasis Area and Severity Index (PASI) 100 scores were 0%, 20.0% (p=0.075 …
At week 12, patients maintaining efficacy response and adequate overall safety were assigned, at the discretion of the investigator, to long …
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Effects of oral care with glutamine in preventing ventilator-associated pneumonia in neurosurgical intensive care unit patients.
Kaya H, Turan Y, Tunalı Y, Aydın GÖ, Yüce N, Gürbüz Ş, Tosun K.
Kaya H, et al. Among authors: gurbuz s.
Appl Nurs Res. 2017 Feb;33:10-14. doi: 10.1016/j.apnr.2016.10.006. Epub 2016 Oct 12.
Appl Nurs Res. 2017.
PMID: 28096000
CONCLUSION: There was no significant difference in using 5% glutamine or 2% chlorhexidine gluconate solution for oral care for the prevention of ventilator-associated pneumonia. Similar studies with bigger sample size and longer term should be conducted for better results. …
CONCLUSION: There was no significant difference in using 5% glutamine or 2% chlorhexidine gluconate solution for oral care for the preventio …
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Benefit of cardiac sonography for estimating the early term survival of the cardiopulmonary arrest patients.
Cebicci H, Salt O, Gurbuz S, Koyuncu S, Bol O.
Cebicci H, et al. Among authors: gurbuz s.
Hippokratia. 2014 Apr;18(2):125-9.
Hippokratia. 2014.
PMID: 25336874
Free PMC article.
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