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Long-Term Follow-Up in Patients Undergoing Renal Mass Biopsy: Seeding is not Anecdotal.
Staehler M, Rodler S, Brinkmann I, Stief CG, Graser A, Götz M, Herlemann A. Staehler M, et al. Among authors: gotz m. Clin Genitourin Cancer. 2024 Apr;22(2):189-192. doi: 10.1016/j.clgc.2023.10.012. Epub 2023 Nov 2. Clin Genitourin Cancer. 2024. PMID: 37985332
INTRODUCTION: Renal biopsy is recommended if the outcome might alter therapeutic decisions for patients who present with renal masses of unclear etiology. However, little is known about long-term risks related to this procedure. PATIENTS AND METHODS: We performed a retrosp …
INTRODUCTION: Renal biopsy is recommended if the outcome might alter therapeutic decisions for patients who present with renal masses of unc …
Noise-optimized ultrastable low-noise current amplifier.
Krause C, Drung D, Götz M, Scherer H. Krause C, et al. Among authors: gotz m. Rev Sci Instrum. 2019 Jan;90(1):014706. doi: 10.1063/1.5078572. Rev Sci Instrum. 2019. PMID: 30709211
It involves a thin-film resistor network with 6.75 Gomega at the high-ohmic path which reduces the noise level to 1.6 fA/Hz. Noise investigations as well as short-term and long-term stability studies were carried out. The stability of the input current gain was meas …
It involves a thin-film resistor network with 6.75 Gomega at the high-ohmic path which reduces the noise level to 1.6 fA/Hz. Noise investiga …
Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration.
Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ, Schotta G, Götz M. Ramesh V, et al. Among authors: gotz m. Genes Dev. 2016 Oct 1;30(19):2199-2212. doi: 10.1101/gad.284992.116. Genes Dev. 2016. PMID: 27798843 Free PMC article.
In order to understand whether early epigenetic mechanisms instruct the long-term behavior of neural stem cells (NSCs) and their progeny, we examined Uhrf1 (ubiquitin-like PHD ring finger-1; also known as Np95), as it is highly expressed in NSCs of the developing brain and …
In order to understand whether early epigenetic mechanisms instruct the long-term behavior of neural stem cells (NSCs) and their prog …
Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis.
Götz M, Sirko S, Beckers J, Irmler M. Götz M, et al. Glia. 2015 Aug;63(8):1452-68. doi: 10.1002/glia.22850. Epub 2015 May 12. Glia. 2015. PMID: 25965557 Free PMC article. Review.
In vitro, however, especially cells cultured under neurosphere conditions reveal a larger potential and long-term self-renewal under the influence of growth factors. This is rather well comparable to reactive astrocytes in the traumatic or ischemic brain some of which acqu …
In vitro, however, especially cells cultured under neurosphere conditions reveal a larger potential and long-term self-renewal under …
In vivo contribution of nestin- and GLAST-lineage cells to adult hippocampal neurogenesis.
DeCarolis NA, Mechanic M, Petrik D, Carlton A, Ables JL, Malhotra S, Bachoo R, Götz M, Lagace DC, Eisch AJ. DeCarolis NA, et al. Among authors: gotz m. Hippocampus. 2013 Aug;23(8):708-19. doi: 10.1002/hipo.22130. Epub 2013 May 17. Hippocampus. 2013. PMID: 23554226 Free PMC article.
We first used these inducible fate-tracking transgenic lines to define the similarities and differences in the contribution of nestin- and GLAST-lineage cells to basal long-term hippocampal neurogenesis. We then explored the ability of nestin- and GLAST-lineage RGCs to con …
We first used these inducible fate-tracking transgenic lines to define the similarities and differences in the contribution of nestin- and G …
Long-term genetic fate mapping of adult generated neurons in a mouse temporal lobe epilepsy model.
Jafari M, Soerensen J, Bogdanović RM, Dimou L, Götz M, Potschka H. Jafari M, et al. Among authors: gotz m. Neurobiol Dis. 2012 Dec;48(3):454-63. doi: 10.1016/j.nbd.2012.06.014. Epub 2012 Jun 30. Neurobiol Dis. 2012. PMID: 22750527
In the epileptic brain, seizures can increase hippocampal neurogenesis, while opposingly seizure-associated brain pathology has been shown to detrimentally affect neurogenesis. The long-term impact of recurrent seizures on the number of new neurons as well as their relativ …
In the epileptic brain, seizures can increase hippocampal neurogenesis, while opposingly seizure-associated brain pathology has been shown t …
Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes.
Ott C, Ross K, Straub S, Thiede B, Götz M, Goosmann C, Krischke M, Mueller MJ, Krohne G, Rudel T, Kozjak-Pavlovic V. Ott C, et al. Among authors: gotz m. Mol Cell Biol. 2012 Mar;32(6):1173-88. doi: 10.1128/MCB.06388-11. Epub 2012 Jan 17. Mol Cell Biol. 2012. PMID: 22252321 Free PMC article.
We provide evidence that the SAM components exist in a large protein complex together with the IMM proteins mitofilin and CHCHD3, which we term the mitochondrial intermembrane space bridging (MIB) complex. ...After destabilization of the MIB complex, we observed deficiency …
We provide evidence that the SAM components exist in a large protein complex together with the IMM proteins mitofilin and CHCHD3, which we …
Stab wound injury of the zebrafish telencephalon: a model for comparative analysis of reactive gliosis.
Baumgart EV, Barbosa JS, Bally-Cuif L, Götz M, Ninkovic J. Baumgart EV, et al. Among authors: gotz m. Glia. 2012 Mar;60(3):343-57. doi: 10.1002/glia.22269. Epub 2011 Nov 21. Glia. 2012. PMID: 22105794
Thus, these data suggest that the specific glial environment in the adult zebrafish telencephalon is not only permissive for long-term neuronal survival, but avoids scar formation. Invasive injury in the adult zebrafish telencephalon may therefore provide a useful model to …
Thus, these data suggest that the specific glial environment in the adult zebrafish telencephalon is not only permissive for long-term
The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.
Asami M, Pilz GA, Ninkovic J, Godinho L, Schroeder T, Huttner WB, Götz M. Asami M, et al. Among authors: gotz m. Development. 2011 Dec;138(23):5067-78. doi: 10.1242/dev.074591. Epub 2011 Oct 26. Development. 2011. PMID: 22031545
In addition, lack of Pax6 also results in premature delamination of progenitor cells from the apical surface due to an overall decrease in proteins mediating anchoring at the ventricular surface. Moreover, continuous long-term imaging in vitro revealed that Pax6-deficient …
In addition, lack of Pax6 also results in premature delamination of progenitor cells from the apical surface due to an overall decrease in p …
Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate.
Rothenaigner I, Krecsmarik M, Hayes JA, Bahn B, Lepier A, Fortin G, Götz M, Jagasia R, Bally-Cuif L. Rothenaigner I, et al. Among authors: gotz m. Development. 2011 Apr;138(8):1459-69. doi: 10.1242/dev.058156. Epub 2011 Mar 2. Development. 2011. PMID: 21367818
We further demonstrate that blocking Notch signaling results in a significant increase in proliferating cells and in the numbers of clones, but does not affect clone composition, demonstrating that Notch primarily controls proliferation rather than cell fate. Finally, through lon …
We further demonstrate that blocking Notch signaling results in a significant increase in proliferating cells and in the numbers of clones, …
31 results