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DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.
J Clin Invest. 2017 Aug 1;127(8):3090-3102. doi: 10.1172/JCI91095. Epub 2017 Jul 17.
J Clin Invest. 2017.
PMID: 28714863
Free PMC article.
Here, we profiled DNA methylation markers to identify a methylation of TIL (MeTIL) signature that recapitulates TIL evaluations and their prognostic value for long-term outcomes in breast cancer (BC). METHODS: MeTIL signature scores were correlated with clinical endpoints …
Here, we profiled DNA methylation markers to identify a methylation of TIL (MeTIL) signature that recapitulates TIL evaluations and their pr …
DNA methylation and histone modifications: teaming up to silence genes.
Fuks F.
Fuks F.
Curr Opin Genet Dev. 2005 Oct;15(5):490-5. doi: 10.1016/j.gde.2005.08.002.
Curr Opin Genet Dev. 2005.
PMID: 16098738
Review.
Recent advances highlight an essential, intricate web of interactions among these processes, generating a self-reinforcing, self-perpetuating cycle of epigenetic events that lead to long-term transcriptional repression. Histone deacetylation and methylation at lysine 9 of …
Recent advances highlight an essential, intricate web of interactions among these processes, generating a self-reinforcing, self-perpetuatin …
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