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Changes in the clinical spectrum of pediatric moyamoya disease over 40 years.
Fujioka M, Hara S, Mukawa M, Karakama J, Inaji M, Tanaka Y, Nariai T, Maehara T. Fujioka M, et al. Childs Nerv Syst. 2023 May;39(5):1215-1223. doi: 10.1007/s00381-023-05852-0. Epub 2023 Feb 15. Childs Nerv Syst. 2023. PMID: 36790492
OBJECTIVE: To investigate the chronological changes in the clinical presentation and long-term prognosis of pediatric-onset moyamoya disease in our institute over 40 years. METHODS: We evaluated 282 pediatric-onset ( 15 years old) moyamoya disease patients who visited our …
OBJECTIVE: To investigate the chronological changes in the clinical presentation and long-term prognosis of pediatric-onset moyamoya …
Surface area in the insula was associated with 28-month functional outcome in first-episode psychosis.
Koike S, Fujioka M, Satomura Y, Koshiyama D, Tada M, Sakakibara E, Okada N, Takano Y, Iwashiro N, Natsubori T, Zhu Y, Abe O, Kirihara K, Yamasue H, Kasai K. Koike S, et al. Among authors: fujioka m. NPJ Schizophr. 2021 Nov 29;7(1):56. doi: 10.1038/s41537-021-00186-9. NPJ Schizophr. 2021. PMID: 34845247 Free PMC article.
However, no study has investigated the relationship between multi-modal measurements and long-term outcomes for >2 years. Thirty-eight individuals with UHR and 29 patients with FEP were measured using one or more modalities (cognitive battery, electrophysiological respo …
However, no study has investigated the relationship between multi-modal measurements and long-term outcomes for >2 years. Thirty-e …
[Pharmacological and clinical study results of Berotralstat Hydrochloride for long-term prophylactic treatment of hereditary angioedema].
Orui S, Nozue H, Kobayashi S, Fujioka M, Maekawa Y. Orui S, et al. Among authors: fujioka m. Nihon Yakurigaku Zasshi. 2021;156(6):382-390. doi: 10.1254/fpj.21069. Nihon Yakurigaku Zasshi. 2021. PMID: 34719573 Japanese.
Therapy of HAE consists of on-demand treatment for acute attack and prophylactic treatment by suppressing the onset of acute attack in the short and long term. However, no drug has been approved for long-term prophylaxis in Japan. ...In conclusion, preclinical and c …
Therapy of HAE consists of on-demand treatment for acute attack and prophylactic treatment by suppressing the onset of acute attack in the s …
Three cases of otitis media caused by Mycobacterium abscessus subsp. abscessus: Importance of medical treatment and efficacy of surgery.
Nishiyama Y, Nishiyama T, Kanzaki S, Oishi N, Fujioka M, Yamada H, Ebisuno C, Kaiho M, Uwamino Y, Fukano H, Hoshino Y, Hasegawa N, Ogawa K. Nishiyama Y, et al. Among authors: fujioka m. J Infect Chemother. 2021 Aug;27(8):1251-1257. doi: 10.1016/j.jiac.2021.04.012. Epub 2021 Apr 29. J Infect Chemother. 2021. PMID: 33934919
Otorrhea was resolved several months after the initiation of long-term multiantibiotic therapy in all cases. The timing of surgery varied among patients. ...From three cases, it is suggested that the mainstay of treatment for M. abscessus subsp. abscessus is long-term …
Otorrhea was resolved several months after the initiation of long-term multiantibiotic therapy in all cases. The timing of surgery va …
Efficacy and Cardiovascular Adverse Events of Long-term Treatment with Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Report from the Nagasaki CML Study Group.
Chiwata M, Itonaga H, Sato S, Hashimoto M, Fujioka M, Kasai S, Sakamoto H, Toriyama E, Nakashima J, Kamijo R, Kitanosono H, Kobayashi Y, Horai M, Taguchi M, Matsuo M, Makiyama J, Takasaki Y, Matsuo E, Horio K, Ando K, Sawayama Y, Taguchi J, Kawaguchi Y, Tsushima H, Imanishi D, Imaizumi Y, Yoshida S, Jo T, Nonaka H, Moriuchi Y, Nagai K, Yokota KI, Hata T, Miyazaki Y. Chiwata M, et al. Among authors: fujioka m. Intern Med. 2021 Jul 15;60(14):2207-2216. doi: 10.2169/internalmedicine.6620-20. Epub 2021 Feb 22. Intern Med. 2021. PMID: 33612681 Free PMC article.
Recent studies have identified cardiovascular diseases (CVDs) as late adverse events (AEs) related to TKIs. In this study, we evaluated the long-term efficacy and AEs of TKIs, focusing on CVDs. Methods We performed a retrospective survey of CML patients (diagnosed from 200 …
Recent studies have identified cardiovascular diseases (CVDs) as late adverse events (AEs) related to TKIs. In this study, we evaluated the …
Long-term administration of excess zinc impairs learning and memory in aged mice.
Yoshida K, Gi M, Fujioka M, Teramoto I, Wanibuchi H. Yoshida K, et al. Among authors: fujioka m. J Toxicol Sci. 2019;44(10):681-691. doi: 10.2131/jts.44.681. J Toxicol Sci. 2019. PMID: 31588059 Free article.
Indeed, the prevalence of senile dementia such as Alzheimer's disease, Parkinson's disease, and vascular-type dementia increases with age. As such, we investigated the effects of long-term exposure to excess Zn on learning and memory in aged mice. ICR-JCL female mice (aged …
Indeed, the prevalence of senile dementia such as Alzheimer's disease, Parkinson's disease, and vascular-type dementia increases with age. A …
Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.
Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K. Hosoya M, et al. Among authors: fujioka m. Regen Ther. 2018 Dec 17;10:54-63. doi: 10.1016/j.reth.2018.11.001. eCollection 2019 Jun. Regen Ther. 2018. PMID: 30581897 Free PMC article.
Moreover, we showed that rapamycin can relieve cell death. However, studies regarding long-term cell survival without cell stressors that mimic the natural course of disease or the rational minimum concentration of rapamycin that prevents cell death are missing. ...RESULTS …
Moreover, we showed that rapamycin can relieve cell death. However, studies regarding long-term cell survival without cell stressors …
Auditory gamma oscillations predict global symptomatic outcome in the early stages of psychosis: A longitudinal investigation.
Koshiyama D, Kirihara K, Tada M, Nagai T, Fujioka M, Ichikawa E, Ohta K, Tani M, Tsuchiya M, Kanehara A, Morita K, Sawada K, Matsuoka J, Satomura Y, Koike S, Suga M, Araki T, Kasai K. Koshiyama D, et al. Among authors: fujioka m. Clin Neurophysiol. 2018 Nov;129(11):2268-2275. doi: 10.1016/j.clinph.2018.08.007. Epub 2018 Aug 30. Clin Neurophysiol. 2018. PMID: 30216911
Although previous cross-sectional studies have shown that gamma-band ASSR is reduced in early psychosis, whether reduced gamma-band ASSR could be a predictor of the long-term prognosis remains unknown. METHODS: In this longitudinal study, we investigated the association be …
Although previous cross-sectional studies have shown that gamma-band ASSR is reduced in early psychosis, whether reduced gamma-band ASSR cou …
A carcinogenicity study of diphenylarsinic acid in F344 rats in drinking water for 104 weeks.
Yamaguchi T, Gi M, Fujioka M, Doi K, Okuno T, Kakehashi A, Wanibuchi H. Yamaguchi T, et al. Among authors: fujioka m. J Toxicol Sci. 2017;42(4):475-483. doi: 10.2131/jts.42.475. J Toxicol Sci. 2017. PMID: 28717106 Free article.
We previously demonstrated that DPAA promotes diethylnitrosamine-induced liver carcinogenesis in a medium-term rat liver bioassay. The purpose of the present study was to evaluate the potential carcinogenicity of DPAA, including investigation of whether the bile duct hyper …
We previously demonstrated that DPAA promotes diethylnitrosamine-induced liver carcinogenesis in a medium-term rat liver bioassay. Th …
Diphenylarsinic acid exerts promotion effects on hepatobiliary carcinogenesis in a rat medium-term multiorgan carcinogenicity bioassay.
Ishii N, Gi M, Fujioka M, Yamano S, Okumura M, Kakehashi A, Wanibuchi H. Ishii N, et al. Among authors: fujioka m. J Toxicol Pathol. 2017 Jan;30(1):39-45. doi: 10.1293/tox.2016-0049. Epub 2016 Oct 23. J Toxicol Pathol. 2017. PMID: 28190923 Free PMC article.
We have previously demonstrated that diphenylarsinic acid (DPAA) promotes liver carcinogenesis in rats in a medium-term liver carcinogenicity bioassay. However, the effects of DPAA on other organs have not been determined. ...In conclusion, our results demonstrate that DPA …
We have previously demonstrated that diphenylarsinic acid (DPAA) promotes liver carcinogenesis in rats in a medium-term liver carcino …
25 results