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Phenserine efficacy in Alzheimer's disease.
Winblad B, Giacobini E, Frölich L, Friedhoff LT, Bruinsma G, Becker RE, Greig NH. Winblad B, et al. Among authors: friedhoff lt. J Alzheimers Dis. 2010;22(4):1201-8. doi: 10.3233/JAD-2010-101311. J Alzheimers Dis. 2010. PMID: 20930279 Free PMC article. Clinical Trial.
Patients who completed 12 weeks of the double-blind before others were continued in the double-blind to determine longer-term treatment effects. At 12 weeks, mean ADAS-cog (AD assessment scale-cognitive) changes from baseline were -2.5 and -1.9 for high-dose phenserine (n= …
Patients who completed 12 weeks of the double-blind before others were continued in the double-blind to determine longer-term treatme …
Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicentre open label extension study.
Rogers SL, Friedhoff LT. Rogers SL, et al. Among authors: friedhoff lt. Eur Neuropsychopharmacol. 1998 Feb;8(1):67-75. doi: 10.1016/s0924-977x(97)00079-5. Eur Neuropsychopharmacol. 1998. PMID: 9452942 Clinical Trial.
The long-term efficacy and safety of donepezil (up to 10 mg/day) was evaluated in a multicentre, non-randomised, open-label extension study of 133 patients with mild to moderate Alzheimer's disease (AD) who had completed a previous 14-week double-blind, placebo-controlled …
The long-term efficacy and safety of donepezil (up to 10 mg/day) was evaluated in a multicentre, non-randomised, open-label extension …