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MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, Liu CG, Bhatt D, Taccioli C, Croce CM. Bloomston M, et al. Among authors: frankel wl. JAMA. 2007 May 2;297(17):1901-8. doi: 10.1001/jama.297.17.1901. JAMA. 2007. PMID: 17473300
Fifteen overexpressed and 8 underexpressed miRNAs differentiated pancreatic cancer from chronic pancreatitis with 93% accuracy. A subgroup of 6 miRNAs was able to distinguish long-term survivors with node-positive disease from those dying within 24 months. ...CONCLUSIONS: …
Fifteen overexpressed and 8 underexpressed miRNAs differentiated pancreatic cancer from chronic pancreatitis with 93% accuracy. A subgroup o …
Cytoreduction results in high perioperative mortality and decreased survival in patients undergoing pancreatectomy for neuroendocrine tumors of the pancreas.
Bloomston M, Muscarella P, Shah MH, Frankel WL, Al-Saif O, Martin EW, Ellison EC. Bloomston M, et al. Among authors: frankel wl. J Gastrointest Surg. 2006 Dec;10(10):1361-70. doi: 10.1016/j.gassur.2006.09.004. J Gastrointest Surg. 2006. PMID: 17175455
Factors predictive of decreased survival were moderate/poor differentiation, R2 resection, and high-risk features. Long-term survival is possible following complete resection for NE tumors of the pancreas. However, cytoreduction resulting in incomplete tumor removal carrie …
Factors predictive of decreased survival were moderate/poor differentiation, R2 resection, and high-risk features. Long-term survival …
Update on pancreatic endocrine tumors.
Frankel WL. Frankel WL. Arch Pathol Lab Med. 2006 Jul;130(7):963-6. doi: 10.5858/2006-130-963-UOPET. Arch Pathol Lab Med. 2006. PMID: 16831051 Free article. Review.
Endocrine tumors of the pancreas represent 1% to 2% of all pancreatic neoplasms. The tumors tend to have an indolent behavior, and long-term survival is common. There is no gender or age predilection. ...
Endocrine tumors of the pancreas represent 1% to 2% of all pancreatic neoplasms. The tumors tend to have an indolent behavior, and long-t …
Evidence for tissue-directed immune responses: analysis of CD4- and CD8-dependent alloimmunity.
Lunsford KE, Gao D, Eiring AM, Wang Y, Frankel WL, Bumgardner GL. Lunsford KE, et al. Among authors: frankel wl. Transplantation. 2004 Oct 27;78(8):1125-33. doi: 10.1097/01.tp.0000138098.19429.99. Transplantation. 2004. PMID: 15502708
CD4-dependent host-immune responses initiated by pancreatic islet allografts were readily suppressed by a variety of short-term immunotherapies, whereas hepatocyte-initiated CD4-dependent alloimmune responses were not. ...
CD4-dependent host-immune responses initiated by pancreatic islet allografts were readily suppressed by a variety of short-term immun …
Hepatocellular adenomatosis is a rare entity that may mimic other hepatocellular lesions.
Skarupa DJ, Ellison EC, Vitellas KM, Frankel WL. Skarupa DJ, et al. Among authors: frankel wl. Ann Diagn Pathol. 2004 Feb;8(1):43-9. doi: 10.1016/j.anndiagpath.2003.11.010. Ann Diagn Pathol. 2004. PMID: 15129911
This case is unique because of the small number of cases of hepatocellular adenomatosis diagnosed in teenagers, and little long-term follow-up....
This case is unique because of the small number of cases of hepatocellular adenomatosis diagnosed in teenagers, and little long-term …
Smooth muscle tumor of the pleura. A case report and review of the literature.
Proca DM, Ross P Jr, Pratt J, Frankel WL. Proca DM, et al. Among authors: frankel wl. Arch Pathol Lab Med. 2000 Nov;124(11):1688-92. doi: 10.5858/2000-124-1688-SMTOTP. Arch Pathol Lab Med. 2000. PMID: 11079027 Free article. Review.
We conclude that smooth muscle tumor of the pleura is a well-defined entity with a low, but definite malignant potential; therefore, we recommend complete resection and long-term follow-up for all patients....
We conclude that smooth muscle tumor of the pleura is a well-defined entity with a low, but definite malignant potential; therefore, we reco …