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Page 1
Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products.
Behne S, Franke H, Schwarz S, Lachenmeier DW. Behne S, et al. Among authors: franke h. Molecules. 2023 Jul 20;28(14):5540. doi: 10.3390/molecules28145540. Molecules. 2023. PMID: 37513412 Free PMC article. Review.
Toxicological, pharmacokinetic, and clinical data from animal and human studies were available for the assessment, which indicated no significant evidence of toxic or adverse effects following acute oral exposure. The current state of knowledge suggests that long-term expo …
Toxicological, pharmacokinetic, and clinical data from animal and human studies were available for the assessment, which indicated no signif …
Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord.
Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson PM, Yeh J, Krügel U, Franke H, Zhang Y, Bo X. Wu D, et al. Among authors: franke h. J Neurosci. 2018 Feb 7;38(6):1351-1365. doi: 10.1523/JNEUROSCI.1660-17.2017. Epub 2017 Dec 26. J Neurosci. 2018. PMID: 29279307 Free PMC article.
Injection of ATP at 150 mum caused little Wallerian degeneration and behavioral tests showed no significant long-term adverse effects on sciatic nerve functions. The results in this study reveal possible mechanisms underlying the stimulation of regenerative programs and su …
Injection of ATP at 150 mum caused little Wallerian degeneration and behavioral tests showed no significant long-term adverse effects …
Comparative risk assessment of tobacco smoke constituents using the margin of exposure approach: the neglected contribution of nicotine.
Baumung C, Rehm J, Franke H, Lachenmeier DW. Baumung C, et al. Among authors: franke h. Sci Rep. 2016 Oct 19;6:35577. doi: 10.1038/srep35577. Sci Rep. 2016. PMID: 27759090 Free PMC article.
Owing to the lack of toxicological data in particular relating to cancer, long term animal testing studies for nicotine are urgently necessary. ...
Owing to the lack of toxicological data in particular relating to cancer, long term animal testing studies for nicotine are urgently …
Muscle energy technique for non-specific low-back pain.
Franke H, Fryer G, Ostelo RW, Kamper SJ. Franke H, et al. Cochrane Database Syst Rev. 2015 Feb 27;2015(2):CD009852. doi: 10.1002/14651858.CD009852.pub2. Cochrane Database Syst Rev. 2015. PMID: 25723574 Free PMC article. Review.
Included studies were typically very small (n = 20 to 72), all except one were assessed as being at high risk of bias, and all reported short-term outcomes. For the purposes of pooling, studies were divided into seven clinically homogenous comparisons according to the pati …
Included studies were typically very small (n = 20 to 72), all except one were assessed as being at high risk of bias, and all reported shor …
Effectiveness of osteopathic manipulative therapy for managing symptoms of irritable bowel syndrome: a systematic review.
Müller A, Franke H, Resch KL, Fryer G. Müller A, et al. Among authors: franke h. J Am Osteopath Assoc. 2014 Jun;114(6):470-9. doi: 10.7556/jaoa.2014.098. J Am Osteopath Assoc. 2014. PMID: 24917634 Free article. Review.
A variety of secondary outcomes were used. All studies reported more pronounced short-term improvements with OMTh compared with sham therapy or standard care only. ...
A variety of secondary outcomes were used. All studies reported more pronounced short-term improvements with OMTh compared with sham …
Toxic Stress: Effects, Prevention and Treatment.
Franke HA. Franke HA. Children (Basel). 2014 Nov 3;1(3):390-402. doi: 10.3390/children1030390. Children (Basel). 2014. PMID: 27417486 Free PMC article. Review.
Children who experience early life toxic stress are at risk of long-term adverse health effects that may not manifest until adulthood. ...
Children who experience early life toxic stress are at risk of long-term adverse health effects that may not manifest until adulthood …
Pathophysiology of astroglial purinergic signalling.
Franke H, Verkhratsky A, Burnstock G, Illes P. Franke H, et al. Purinergic Signal. 2012 Sep;8(3):629-57. doi: 10.1007/s11302-012-9300-0. Epub 2012 May 1. Purinergic Signal. 2012. PMID: 22544529 Free PMC article. Review.
ATP serves as a fast excitatory neurotransmitter and has pronounced long-term (trophic) roles in cell proliferation, growth, and development. ...
ATP serves as a fast excitatory neurotransmitter and has pronounced long-term (trophic) roles in cell proliferation, growth, and deve …
P2Y1 receptors inhibit long-term depression in the prefrontal cortex.
Guzman SJ, Schmidt H, Franke H, Krügel U, Eilers J, Illes P, Gerevich Z. Guzman SJ, et al. Among authors: franke h. Neuropharmacology. 2010 Nov;59(6):406-15. doi: 10.1016/j.neuropharm.2010.05.013. Epub 2010 Jun 4. Neuropharmacology. 2010. PMID: 20570683
Long-term depression (LTD) is a form of synaptic plasticity that may contribute to information storage in the central nervous system. ...
Long-term depression (LTD) is a form of synaptic plasticity that may contribute to information storage in the central nervous system. …
Therapeutic equivalence, long-term efficacy and safety of HX575 in the treatment of anemia in chronic renal failure patients receiving hemodialysis.
Haag-Weber M, Vetter A, Thyroff-Friesinger U; INJ-Study Group. Haag-Weber M, et al. Clin Nephrol. 2009 Nov;72(5):380-90. Clin Nephrol. 2009. PMID: 19863881 Clinical Trial.
The primary objective of the study was the evaluation of therapeutic equivalence in terms of hemoglobin (Hb) response of HX575 compared with the comparator product (EPREX/ ERYPO, Janssen-Cilag/Ortho Biotech, Neuss, Germany) in the long-term intravenous (i.v.) treatment of …
The primary objective of the study was the evaluation of therapeutic equivalence in terms of hemoglobin (Hb) response of HX575 compared with …
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