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5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite.
Lee BWH, Sidhu AS, Francis IC, Coroneo MT. Lee BWH, et al. Among authors: francis ic. Ocul Surf. 2022 Oct;26:128-141. doi: 10.1016/j.jtos.2022.08.002. Epub 2022 Aug 9. Ocul Surf. 2022. PMID: 35961535 Review.
Additional study with extended follow-up is needed to elucidate the optimal dose, frequency, duration, and long-term safety of 5-FU injections. If 5-FU is used in the management of pterygium, it should be with caution, in selected patients and with vigilant long-term …
Additional study with extended follow-up is needed to elucidate the optimal dose, frequency, duration, and long-term safety of 5-FU i …
Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress.
O'Brien KA, McNally BD, Sowton AP, Murgia A, Armitage J, Thomas LW, Krause FN, Maddalena LA, Francis I, Kavanagh S, Williams DP, Ashcroft M, Griffin JL, Lyon JJ, Murray AJ. O'Brien KA, et al. Among authors: francis i. BMC Biol. 2021 Dec 15;19(1):265. doi: 10.1186/s12915-021-01192-0. BMC Biol. 2021. PMID: 34911556 Free PMC article.
RESULTS: Here, we report that hepatic respiratory capacity is enhanced following short-term exposure to hypoxia (2 days, 10% O(2)) and is associated with increased abundance of the respiratory chain supercomplex III(2)+IV and increased cardiolipin levels. ...CONCLUSIONS: T …
RESULTS: Here, we report that hepatic respiratory capacity is enhanced following short-term exposure to hypoxia (2 days, 10% O(2)) an …
A Rare Cause of Chronic Liver Disease Diagnosed by Endoscopic Ultrasound-Guided Liver Biopsy.
Alajeel NA, Shehab M, Francis I, Alali A. Alajeel NA, et al. Among authors: francis i. Am J Case Rep. 2021 Jul 19;22:e933002. doi: 10.12659/AJCR.933002. Am J Case Rep. 2021. PMID: 34276044 Free PMC article.
An EUS-guided liver biopsy confirmed a diagnosis hepatic hemosiderosis secondary to long-term blood transfusions. CONCLUSIONS This report emphasizes the importance of careful monitoring of iron levels in patients with hematological conditions requiring long-term blo …
An EUS-guided liver biopsy confirmed a diagnosis hepatic hemosiderosis secondary to long-term blood transfusions. CONCLUSIONS This re …
Floppy eyelid syndrome "plasty" procedure: Employment of a periosteal transposition flap for surgery of floppy eyelid syndrome.
Waldie AM, Francis IC, Coroneo MT, Wilcsek G. Waldie AM, et al. Among authors: francis ic. Clin Exp Ophthalmol. 2019 Sep;47(7):864-870. doi: 10.1111/ceo.13560. Epub 2019 Jun 17. Clin Exp Ophthalmol. 2019. PMID: 31115955
CONCLUSIONS AND RELEVANCE: FESplasty is likely to confer long-term effective stabilization of the lateral canthal tendon, lateral commissure and superior tarsal plate. ...
CONCLUSIONS AND RELEVANCE: FESplasty is likely to confer long-term effective stabilization of the lateral canthal tendon, lateral com …
Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract.
Islam EA, Anipindi VC, Francis I, Shaik-Dasthagirisaheb Y, Xu S, Leung N, Sintsova A, Amin M, Kaushic C, Wetzler LM, Gray-Owen SD. Islam EA, et al. Among authors: francis i. Infect Immun. 2018 Jul 23;86(8):e00092-18. doi: 10.1128/IAI.00092-18. Print 2018 Aug. Infect Immun. 2018. PMID: 29760215 Free PMC article.
Our results demonstrate that Opa-CEACAM5 binding on vaginal epithelia facilitates the long-term colonization of the lower genital tract, while Opa protein binding to CEACAM1 on uterine epithelia enhances gonococcal association and penetration into these tissues. ...
Our results demonstrate that Opa-CEACAM5 binding on vaginal epithelia facilitates the long-term colonization of the lower genital tra …
Effect of tetrahydrobiopterin on Phe/Tyr ratios and variation in Phe levels in tetrahydrobiopterin responsive PKU patients.
Humphrey M, Nation J, Francis I, Boneh A. Humphrey M, et al. Among authors: francis i. Mol Genet Metab. 2011 Sep-Oct;104(1-2):89-92. doi: 10.1016/j.ymgme.2011.05.011. Epub 2011 May 19. Mol Genet Metab. 2011. PMID: 21624843
Neuropsychological testing in patients who have been treated with BH(4) long term may be able to ascertain the clinical benefit of these biochemical findings....
Neuropsychological testing in patients who have been treated with BH(4) long term may be able to ascertain the clinical benefit of th …
Frequency, outcome, and appropriateness of treatment of nonionic iodinated contrast media reactions.
Wang CL, Cohan RH, Ellis JH, Caoili EM, Wang G, Francis IR. Wang CL, et al. Among authors: francis ir. AJR Am J Roentgenol. 2008 Aug;191(2):409-15. doi: 10.2214/AJR.07.3421. AJR Am J Roentgenol. 2008. PMID: 18647910
Data collected included patient sex and age, symptoms, reaction manifestations, treatment, and long-term sequelae. The appropriateness and efficacy of patient management were assessed. ...Although 99% of the treatments did not result in any complication, three patients may …
Data collected included patient sex and age, symptoms, reaction manifestations, treatment, and long-term sequelae. The appropriatenes …
Nephrogenic systemic fibrosis: a report of 29 cases.
Shabana WM, Cohan RH, Ellis JH, Hussain HK, Francis IR, Su LD, Mukherji SK, Swartz RD. Shabana WM, et al. Among authors: francis ir. AJR Am J Roentgenol. 2008 Mar;190(3):736-41. doi: 10.2214/AJR.07.3115. AJR Am J Roentgenol. 2008. PMID: 18287446
Nephrogenic systemic fibrosis developed in 12 (2.9%) of 414 patients undergoing long-term dialysis who received gadolinium-based contrast material. CONCLUSION: We confirm the strong association between nephrogenic systemic fibrosis and gadolinium-based contrast administrat …
Nephrogenic systemic fibrosis developed in 12 (2.9%) of 414 patients undergoing long-term dialysis who received gadolinium-based cont …
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