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Time-dependent effect of GLP-1 receptor agonists on cardiovascular benefits: a real-world study.
Piccini S, Favacchio G, Panico C, Morenghi E, Folli F, Mazziotti G, Lania AG, Mirani M. Piccini S, et al. Among authors: folli f. Cardiovasc Diabetol. 2023 Mar 25;22(1):69. doi: 10.1186/s12933-023-01800-z. Cardiovasc Diabetol. 2023. PMID: 36966321 Free PMC article.
We analyzed the determinants of GLP-1 RA-mediated CV protection in a real-world population of persons with type 2 diabetes with and without a history of CV events with long-term follow-up. METHODS: Retrospective cohort study of 550 individuals with type 2 diabetes (395 in …
We analyzed the determinants of GLP-1 RA-mediated CV protection in a real-world population of persons with type 2 diabetes with and without …
The IGFBP3/TMEM219 pathway regulates beta cell homeostasis.
D'Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, Loretelli C, Bertuzzi F, Antonioli B, Cardarelli F, El Essawy B, Solini A, Gerling IC, Bianchi C, Becchi G, Mazzucchelli S, Corradi D, Fadini GP, Foschi D, Markmann JF, Orsi E, Škrha J Jr, Camboni MG, Abdi R, James Shapiro AM, Folli F, Ludvigsson J, Del Prato S, Zuccotti G, Fiorina P. D'Addio F, et al. Among authors: folli f. Nat Commun. 2022 Feb 3;13(1):684. doi: 10.1038/s41467-022-28360-2. Nat Commun. 2022. PMID: 35115561 Free PMC article.
Increased peripheral IGFBP3 was observed in established and at-risk T1D/T2D patients and was confirmed in T1D/T2D preclinical models, suggesting that dysfunctional IGFBP3/TMEM219 signaling is associated with abnormalities in beta cells homeostasis. In vitro and in vivo short-t …
Increased peripheral IGFBP3 was observed in established and at-risk T1D/T2D patients and was confirmed in T1D/T2D preclinical models, sugges …
Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection.
Montefusco L, Ben Nasr M, D'Addio F, Loretelli C, Rossi A, Pastore I, Daniele G, Abdelsalam A, Maestroni A, Dell'Acqua M, Ippolito E, Assi E, Usuelli V, Seelam AJ, Fiorina RM, Chebat E, Morpurgo P, Lunati ME, Bolla AM, Finzi G, Abdi R, Bonventre JV, Rusconi S, Riva A, Corradi D, Santus P, Nebuloni M, Folli F, Zuccotti GV, Galli M, Fiorina P. Montefusco L, et al. Among authors: folli f. Nat Metab. 2021 Jun;3(6):774-785. doi: 10.1038/s42255-021-00407-6. Epub 2021 May 25. Nat Metab. 2021. PMID: 34035524 Free PMC article.
Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns.
Assi E, D'Addio F, Mandò C, Maestroni A, Loretelli C, Ben Nasr M, Usuelli V, Abdelsalam A, Seelam AJ, Pastore I, Magagnotti C, Abdi R, El Essawy B, Folli F, Corradi D, Zuccotti G, Cetin I, Fiorina P. Assi E, et al. Among authors: folli f. BMJ Open Diabetes Res Care. 2020 Nov;8(2):e001586. doi: 10.1136/bmjdrc-2020-001586. BMJ Open Diabetes Res Care. 2020. PMID: 33188009 Free PMC article.
INTRODUCTION: Gestational diabetes mellitus (GDM) is the most frequent metabolic complication during pregnancy and is associated with development of short-term and long-term complications for newborns, with large-for-gestational-age (LGA) being particularly common. …
INTRODUCTION: Gestational diabetes mellitus (GDM) is the most frequent metabolic complication during pregnancy and is associated with develo …
Bariatric surgery, compared to medical treatment, reduces morbidity at all ages but does not reduce mortality in patients aged < 43 years, especially if diabetes mellitus is present: a post hoc analysis of two retrospective cohort studies.
Pontiroli AE, Ceriani V, Tagliabue E, Zakaria AS, Veronelli A, Folli F, Zanoni I. Pontiroli AE, et al. Among authors: folli f. Acta Diabetol. 2020 Mar;57(3):323-333. doi: 10.1007/s00592-019-01433-3. Epub 2019 Oct 9. Acta Diabetol. 2020. PMID: 31598798
BACKGROUND AND AIMS: Bariatric surgery (BS) reduces long-term mortality in comparison with medical treatment of obesity. Some studies indicate that this effect is significant for patients above mean age in different cohorts, but not for younger patients. ...Then, we analyz …
BACKGROUND AND AIMS: Bariatric surgery (BS) reduces long-term mortality in comparison with medical treatment of obesity. Some studies …
A 23-year study of mortality and development of co-morbidities in patients with obesity undergoing bariatric surgery (laparoscopic gastric banding) in comparison with medical treatment of obesity.
Pontiroli AE, Zakaria AS, Fanchini M, Osio C, Tagliabue E, Micheletto G, Saibene A, Folli F. Pontiroli AE, et al. Among authors: folli f. Cardiovasc Diabetol. 2018 Dec 29;17(1):161. doi: 10.1186/s12933-018-0801-1. Cardiovasc Diabetol. 2018. PMID: 30594184 Free PMC article.
BACKGROUND AND AIM: Several studies have shown that bariatric surgery reduces long term mortality compared to medical weight loss therapy. In a previous study we have demonstrated that gastric banding (LAGB) is associated with reduced mortality in patients with and without …
BACKGROUND AND AIM: Several studies have shown that bariatric surgery reduces long term mortality compared to medical weight loss the …
A 9 years comparison of weight loss, disappearance of obesity, and resolution of diabetes mellitus with biliointestinal bypass and with adjustable gastric banding: experience of a collaborative network.
Pontiroli AE, Zakaria AS, Micheletto G, Osio C, Saibene A, Folli F; LAGB10 Group. Pontiroli AE, et al. Among authors: folli f. Acta Diabetol. 2019 Feb;56(2):163-169. doi: 10.1007/s00592-018-1221-0. Epub 2018 Nov 9. Acta Diabetol. 2019. PMID: 30411157
AIMS: Long-term comparisons between bariatric surgical techniques have been performed for gastric bypass (RYGB), sleeve gastrectomy (LSG), and biliopancreatic diversion (BPD) vs gastric banding (LAGB), but short-term studies (6 months-4 years) have only compared bil …
AIMS: Long-term comparisons between bariatric surgical techniques have been performed for gastric bypass (RYGB), sleeve gastrectomy ( …
Papio spp. Colon microbiome and its link to obesity in pregnancy.
Li X, Rensing C, Taylor WL, Costelle C, Brejnrod AD, Ferry RJ Jr, Higgins PB, Folli F, Kottapalli KR, Hubbard GB, Dick EJ Jr, Yooseph S, Nelson KE, Schlabritz-Loutsevitch N. Li X, et al. Among authors: folli f. J Med Primatol. 2018 Dec;47(6):393-401. doi: 10.1111/jmp.12366. Epub 2018 Jul 24. J Med Primatol. 2018. PMID: 30039863 Free PMC article.
MATERIAL AND METHODS: Banked tissues were collected under sterile conditions during necropsy, from three non-obese (nOb) and four obese (Ob) near-term pregnant baboons. Sequences were assigned taxonomy using the Ribosomal Database Project classifier. ...
MATERIAL AND METHODS: Banked tissues were collected under sterile conditions during necropsy, from three non-obese (nOb) and four obese (Ob) …
Bariatric surgery and bone disease: from clinical perspective to molecular insights.
Folli F, Sabowitz BN, Schwesinger W, Fanti P, Guardado-Mendoza R, Muscogiuri G. Folli F, et al. Int J Obes (Lond). 2012 Nov;36(11):1373-9. doi: 10.1038/ijo.2012.115. Epub 2012 Jul 17. Int J Obes (Lond). 2012. PMID: 22828943 Review.
Although many studies have demonstrated the efficacy and durability of bariatric surgery for weight loss, there are limited data regarding long-term side effects of these procedures. Recently, there has been an increased focus on the impact of bariatric surgery on bone met …
Although many studies have demonstrated the efficacy and durability of bariatric surgery for weight loss, there are limited data regarding l …
The ontogeny of the endocrine pancreas in the fetal/newborn baboon.
Quinn AR, Blanco CL, Perego C, Finzi G, La Rosa S, Capella C, Guardado-Mendoza R, Casiraghi F, Gastaldelli A, Johnson M, Dick EJ Jr, Folli F. Quinn AR, et al. Among authors: folli f. J Endocrinol. 2012 Sep;214(3):289-99. doi: 10.1530/JOE-12-0070. Epub 2012 Jun 21. J Endocrinol. 2012. PMID: 22723715 Free PMC article.
Twelve fetal baboons were delivered at 125 days (d) gestational age (GA), 140d GA, or 175d GA. Eight animals were delivered at term (185d GA); half were fed for 5 days. Seventy-three nondiabetic adult baboons were used for comparison. ...Developmental differences may play …
Twelve fetal baboons were delivered at 125 days (d) gestational age (GA), 140d GA, or 175d GA. Eight animals were delivered at term ( …
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