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Clinical evaluation and treatment in men with low testosterone levels and prostate cancer.
Ljubetic BM, Parada F, Flores JM. Ljubetic BM, et al. Among authors: flores jm. Actas Urol Esp (Engl Ed). 2023 Dec 13:S2173-5786(23)00137-3. doi: 10.1016/j.acuroe.2023.12.001. Online ahead of print. Actas Urol Esp (Engl Ed). 2023. PMID: 38101513 Review. English, Spanish.
RESULTS: According to the published evidence to date, testosterone therapy in men with prostate cancer does not increase the risk of prostate cancer recurrence in the short and medium term, but there is a lack of data on the long term. Symptomatic men with low testo …
RESULTS: According to the published evidence to date, testosterone therapy in men with prostate cancer does not increase the risk of prostat …
Comparison of APIStrip passive sampling with conventional sample techniques for the control of acaricide residues in honey bee hives.
Luna A, Murcia-Morales M, Hernando MD, Van der Steen JJM, Fernández-Alba AR, Flores JM. Luna A, et al. Among authors: flores jm. Sci Total Environ. 2023 Dec 20;905:167205. doi: 10.1016/j.scitotenv.2023.167205. Epub 2023 Sep 19. Sci Total Environ. 2023. PMID: 37730056 Free article.
These practices are undoubtedly aggressive for the colony as a whole, and may affect its normal functioning and even compromise its viability. APIStrip-based passive sampling allows long-term monitoring of residues without affecting the colony in any way. ...
These practices are undoubtedly aggressive for the colony as a whole, and may affect its normal functioning and even compromise its viabilit …
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.
Dwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Dwyer JB, et al. Among authors: flores jm. Focus (Am Psychiatr Publ). 2022 Apr;20(2):241-251. doi: 10.1176/appi.focus.22020004. Epub 2022 Apr 22. Focus (Am Psychiatr Publ). 2022. PMID: 37153136 Free PMC article.
CONCLUSIONS: In this first randomized placebo-controlled clinical trial of intravenous ketamine in adolescents with depression, the findings suggest that it is well tolerated acutely and has significant short-term (2-week) efficacy in reducing depressive symptoms compared …
CONCLUSIONS: In this first randomized placebo-controlled clinical trial of intravenous ketamine in adolescents with depression, the findings …
The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis.
Farhat LC, Flores JM, Behling E, Avila-Quintero VJ, Lombroso A, Cortese S, Polanczyk GV, Bloch MH. Farhat LC, et al. Among authors: flores jm. Mol Psychiatry. 2022 Mar;27(3):1562-1572. doi: 10.1038/s41380-021-01391-9. Epub 2022 Jan 14. Mol Psychiatry. 2022. PMID: 35027679
Additional research is required to investigate potential long-term effects of using high doses of stimulants in clinical practice....
Additional research is required to investigate potential long-term effects of using high doses of stimulants in clinical practice....
Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial.
Dwyer JB, Landeros-Weisenberger A, Johnson JA, Londono Tobon A, Flores JM, Nasir M, Couloures K, Sanacora G, Bloch MH. Dwyer JB, et al. Among authors: flores jm. Am J Psychiatry. 2021 Apr 1;178(4):352-362. doi: 10.1176/appi.ajp.2020.20010018. Epub 2021 Mar 3. Am J Psychiatry. 2021. PMID: 33653121 Clinical Trial.
CONCLUSIONS: In this first randomized placebo-controlled clinical trial of intravenous ketamine in adolescents with depression, the findings suggest that it is well tolerated acutely and has significant short-term (2-week) efficacy in reducing depressive symptoms compared …
CONCLUSIONS: In this first randomized placebo-controlled clinical trial of intravenous ketamine in adolescents with depression, the findings …
Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.
Barriales D, Martín-Ruiz I, Carreras-González A, Montesinos-Robledo M, Azkargorta M, Iloro I, Escobés I, Martín-Mateos T, Atondo E, Palacios A, Gonzalez-Lopez M, Bárcena L, Cortázar AR, Cabrera D, Peña-Cearra A, van Liempd SM, Falcón-Pérez JM, Pascual-Itoiz MA, Flores JM, Abecia L, Pellon A, Martínez-Chantar ML, Aransay AM, Pascual A, Elortza F, Berra E, Lavín JL, Rodríguez H, Anguita J. Barriales D, et al. Among authors: flores jm. PLoS Biol. 2021 Jan 4;19(1):e3001062. doi: 10.1371/journal.pbio.3001062. eCollection 2021 Jan. PLoS Biol. 2021. PMID: 33395408 Free PMC article.
Here, we identify broad transcriptomic and proteomic changes in the heart during infection that reveal a profound down-regulation of mitochondrial components. We also describe the long-term functional modulation of macrophages exposed to live bacteria, characterized by an …
Here, we identify broad transcriptomic and proteomic changes in the heart during infection that reveal a profound down-regulation of mitocho …
The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant.
Tomás-Cortázar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MÁ, de Juan VG, Caro-Maldonado A, Merino N, Marina A, Blanco FJ, Flores JM, Sutherland JD, Barrio R, Rojas A, Martínez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J. Tomás-Cortázar J, et al. Among authors: flores jm. Sci Rep. 2017 Sep 6;7(1):10740. doi: 10.1038/s41598-017-11354-2. Sci Rep. 2017. PMID: 28878331 Free PMC article.
The fate of the CD4 T cells activated in the presence of Salp15 or its long-term effects are, however, unknown. We now show that Salp15 binding to CD4 is persistent and induces a long-lasting immunomodulatory effect. ...Our study provides a profound characterization of the …
The fate of the CD4 T cells activated in the presence of Salp15 or its long-term effects are, however, unknown. We now show that Salp …
Preoperative Radiotherapy Is Not Associated with Increased Post-mastectomy Short-term Morbidity: Analysis of 77,902 Patients.
Baltodano PA, Reinhardt ME, Flores JM, Abreu FM, Chattha A, Kone L, Cooney CM, Manahan MA, Zellars RC, Rosson GD. Baltodano PA, et al. Among authors: flores jm. Plast Reconstr Surg Glob Open. 2017 Mar 13;5(3):e1108. doi: 10.1097/GOX.0000000000001108. eCollection 2017 Mar. Plast Reconstr Surg Glob Open. 2017. PMID: 28458959 Free PMC article.
Neurocognitive testing and cochlear implantation: insights into performance in older adults.
Cosetti MK, Pinkston JB, Flores JM, Friedmann DR, Jones CB, Roland JT Jr, Waltzman SB. Cosetti MK, et al. Among authors: flores jm. Clin Interv Aging. 2016 May 12;11:603-13. doi: 10.2147/CIA.S100255. eCollection 2016. Clin Interv Aging. 2016. PMID: 27274210 Free PMC article.
MEASUREMENTS: A neurocognitive battery of 20 tests assessing intellectual function, learning, short- and long-term memory, verbal fluency, attention, mental flexibility, and processing speed was performed prior to and 2-4.1 years (mean, 3.7) after cochlear implant (CI). .. …
MEASUREMENTS: A neurocognitive battery of 20 tests assessing intellectual function, learning, short- and long-term memory, verbal flu …
Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage.
García-Beccaria M, Martínez P, Méndez-Pertuz M, Martínez S, Blanco-Aparicio C, Cañamero M, Mulero F, Ambrogio C, Flores JM, Megias D, Barbacid M, Pastor J, Blasco MA. García-Beccaria M, et al. Among authors: flores jm. EMBO Mol Med. 2015 Jul;7(7):930-49. doi: 10.15252/emmm.201404497. EMBO Mol Med. 2015. PMID: 25971796 Free PMC article.
This is accompanied by induction of telomeric DNA damage, apoptosis, decreased proliferation, and G2 arrest. Long-term whole-body Trf1 deletion in adult mice did not impact on mouse survival and viability, although some mice showed a moderately decreased cellularity in bon …
This is accompanied by induction of telomeric DNA damage, apoptosis, decreased proliferation, and G2 arrest. Long-term whole-body Trf …
15 results