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Infant gut DNA bacteriophage strain persistence during the first 3 years of life.
Cell Host Microbe. 2024 Jan 10;32(1):35-47.e6. doi: 10.1016/j.chom.2023.11.015. Epub 2023 Dec 13.
Cell Host Microbe. 2024.
PMID: 38096814
Free article.
Here, we establish a large phage sequence database and use strain-resolved analyses to investigate DNA phage succession in infants throughout the first 3 years of life. Analysis of 819 fecal metagenomes collected from 28 full-term and 24 preterm infants and their mothers r …
Here, we establish a large phage sequence database and use strain-resolved analyses to investigate DNA phage succession in infants throughou …
Infant gut strain persistence is associated with maternal origin, phylogeny, and traits including surface adhesion and iron acquisition.
Lou YC, Olm MR, Diamond S, Crits-Christoph A, Firek BA, Baker R, Morowitz MJ, Banfield JF.
Lou YC, et al. Among authors: firek ba.
Cell Rep Med. 2021 Sep 7;2(9):100393. doi: 10.1016/j.xcrm.2021.100393. eCollection 2021 Sep 21.
Cell Rep Med. 2021.
PMID: 34622230
Free PMC article.
Here, we perform strain-resolved analyses to compare gut colonization of preterm and full-term infants throughout the first year of life and evaluate associations between strain persistence and strain origin as well as genetic potential. Analysis of fecal metagenomes colle …
Here, we perform strain-resolved analyses to compare gut colonization of preterm and full-term infants throughout the first year of l …
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Safety, Clinical Response, and Microbiome Findings Following Fecal Microbiota Transplant in Children With Inflammatory Bowel Disease.
Goyal A, Yeh A, Bush BR, Firek BA, Siebold LM, Rogers MB, Kufen AD, Morowitz MJ.
Goyal A, et al. Among authors: firek ba.
Inflamm Bowel Dis. 2018 Jan 18;24(2):410-421. doi: 10.1093/ibd/izx035.
Inflamm Bowel Dis. 2018.
PMID: 29361092
CONCLUSIONS: A single FMT is relatively safe and can result in a short-term response in young patients with active IBD. Responders possessed increased Fusobacterium prior to FMT and demonstrated more significant microbiome changes compared with nonresponders after FMT. ...
CONCLUSIONS: A single FMT is relatively safe and can result in a short-term response in young patients with active IBD. Responders po …
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Strain-resolved analysis of hospital rooms and infants reveals overlap between the human and room microbiome.
Brooks B, Olm MR, Firek BA, Baker R, Thomas BC, Morowitz MJ, Banfield JF.
Brooks B, et al. Among authors: firek ba.
Nat Commun. 2017 Nov 27;8(1):1814. doi: 10.1038/s41467-017-02018-w.
Nat Commun. 2017.
PMID: 29180750
Free PMC article.
Preterm infants exhibit different microbiome colonization patterns relative to full-term infants, and it is speculated that the hospital room environment may contribute to infant microbiome development. ...
Preterm infants exhibit different microbiome colonization patterns relative to full-term infants, and it is speculated that the hospi …
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Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants.
Brooks B, Firek BA, Miller CS, Sharon I, Thomas BC, Baker R, Morowitz MJ, Banfield JF.
Brooks B, et al. Among authors: firek ba.
Microbiome. 2014 Jan 28;2(1):1. doi: 10.1186/2049-2618-2-1.
Microbiome. 2014.
PMID: 24468033
Free PMC article.
BACKGROUND: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by delivery mode in full-term infants, but these influences may be decoupled in very low birth weight (VLBW, <1,500 g) neonates via conventional broad-spectrum antibiot …
BACKGROUND: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by delivery mode in full-term infants, …
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