Bioengineered hydrogels enhance ex vivo preservation of patient-derived tumor explants for drug evaluation.
Adine C, Fernando K, Ho NCW, Quah HS, Ho SSW, Wu KZ, Teng KWW, Arcinas C, Li L, Ha K, Chew JWL, Wang C, Too NSH, Yeong JPS, Tan DSW, Tan IBH, Nagadia R, Chia CS, Macalinao D, Bhuvaneswari H, Iyer NG, Fong ELS.
Adine C, et al. Among authors: fernando k.
Biomaterials. 2024 Mar;305:122460. doi: 10.1016/j.biomaterials.2023.122460. Epub 2024 Jan 2.
Biomaterials. 2024.
PMID: 38246018
Ex vivo patient-derived tumor slices (PDTS) are currently limited by short-term viability in culture. Here, we show how bioengineered hydrogels enable the identification of key matrix parameters that significantly enhance PDTS viability compared to conventional culture sys …
Ex vivo patient-derived tumor slices (PDTS) are currently limited by short-term viability in culture. Here, we show how bioengineered …