DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma.
Filipski K, Scherer M, Zeiner KN, Bucher A, Kleemann J, Jurmeister P, Hartung TI, Meissner M, Plate KH, Fenton TR, Walter J, Tierling S, Schilling B, Zeiner PS, Harter PN.
Filipski K, et al. Among authors: fenton tr.
J Immunother Cancer. 2021 Jul;9(7):e002226. doi: 10.1136/jitc-2020-002226.
J Immunother Cancer. 2021.
PMID: 34281986
Free PMC article.
BACKGROUND: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking. METHODS: A novel approach of reference-free deconvolution of large-sc …
BACKGROUND: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, …