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Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women.
Bolton-Smith C, McMurdo ME, Paterson CR, Mole PA, Harvey JM, Fenton ST, Prynne CJ, Mishra GD, Shearer MJ. Bolton-Smith C, et al. Among authors: fenton st. J Bone Miner Res. 2007 Apr;22(4):509-19. doi: 10.1359/jbmr.070116. J Bone Miner Res. 2007. PMID: 17243866 Free article. Clinical Trial.
The substantial increase in gamma-carboxylation of osteocalcin by vitamin K may have long-term benefits and is potentially achievable by increased dietary intakes of vitamin K rather than by supplementation....
The substantial increase in gamma-carboxylation of osteocalcin by vitamin K may have long-term benefits and is potentially achievable …