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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design.
Gross R, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Witvliet MG, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Buchbinder NC, Bueler E, Bükülmez H, Casey BJ, Chang L, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Harahsheh AS, Heath AC, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Iacono WG, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Lim PPC, Lisdahl KM, McCrindle BW, McCulloh RJ, Mendels… See abstract for full author list ➔ Gross R, et al. Among authors: faustino evs. medRxiv [Preprint]. 2023 May 12:2023.04.27.23289228. doi: 10.1101/2023.04.27.23289228. medRxiv. 2023. PMID: 37214806 Free PMC article. Updated. Preprint.
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. ...CONCLUSIONS AND RELEVANCE: RECOVER-Pediatrics seeks to characterize the clinical cours …
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long CO …
"I Didn't Want My Baby to Pass, But I Didn't Want Him Suffering Either": Comparing Bereaved Parents' Narratives With Nursing End-of-Life Assessments in the Pediatric Intensive Care Unit.
Broden EG, Hinds PS, Werner-Lin AV, Curley MAQ; for the RESTORE Study Investigators. Broden EG, et al. J Hosp Palliat Nurs. 2022 Oct 1;24(5):271-280. doi: 10.1097/NJH.0000000000000884. Epub 2022 Jun 6. J Hosp Palliat Nurs. 2022. PMID: 35666188 Free PMC article.
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, contextualize, and examine comparisons between quantitative trends in children's end-of-life care and parents' qualitative perceptions. ...
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, cont …
Recommendations for standardized definitions, clinical assessment, and future research in pediatric clinically unsuspected venous thromboembolism: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis.
Betensky M, Kulkarni K, Rizzi M, Jones S, Brandão LR, Faustino EVS, Goldenberg NA, Sharathkumar A. Betensky M, et al. Among authors: faustino evs. J Thromb Haemost. 2022 Jul;20(7):1729-1734. doi: 10.1111/jth.15731. Epub 2022 May 15. J Thromb Haemost. 2022. PMID: 35570328 Free PMC article. Review.
These recommendations will serve to enhance the quantity and quality of evidence on the topic and facilitate the design and execution of cooperative observational studies, and interventional trials of risk-stratified management approaches aimed at preventing and optimizing long- …
These recommendations will serve to enhance the quantity and quality of evidence on the topic and facilitate the design and execution of coo …
Refining the Pediatric Multiple Organ Dysfunction Syndrome.
Weiss SL, Carcillo JA, Leclerc F, Leteurtre S, Schlapbach LJ, Tissieres P, Wynn JL, Lacroix J; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative. Weiss SL, et al. Pediatrics. 2022 Jan 1;149(1 Suppl 1):S13-S22. doi: 10.1542/peds.2021-052888C. Pediatrics. 2022. PMID: 34970671 Free PMC article.
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has been applied broadly to any patient with >1 concurrent organ dysfunction. However, the epidemiology, mechanisms, time course, and outcomes …
Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has b …
Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT).
Hirshberg EL, Alexander JL, Asaro LA, Coughlin-Wells K, Steil GM, Spear D, Stone C, Nadkarni VM, Agus MSD; HALF-PINT Study Investigators. Hirshberg EL, et al. Chest. 2021 Sep;160(3):919-928. doi: 10.1016/j.chest.2021.04.049. Epub 2021 Apr 29. Chest. 2021. PMID: 33932465 Free PMC article.
CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01565941, registered March 29 2012; https://clinicaltrials.gov/ct2/show/NCT01565941?term=HALF-PINT&draw=2&rank=1....
CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01565941, registered March 29 2012; https://clinicaltrials.gov/ct2/show/NCT01 …
Weight as a Risk Factor for Mortality in Critically Ill Patients.
Ayalon I, Woo JG, Basu RK, Kaddourah A, Goldstein SL, Kaplan JM; AWARE Investigators. Ayalon I, et al. Pediatrics. 2020 Aug;146(2):e20192829. doi: 10.1542/peds.2019-2829. Epub 2020 Jul 3. Pediatrics. 2020. PMID: 32620676 Free PMC article.
CONCLUSIONS: Patients who are underweight make up a significant proportion of all patients in the PICU, have a higher short-term mortality rate, and have a more complicated ICU course....
CONCLUSIONS: Patients who are underweight make up a significant proportion of all patients in the PICU, have a higher short-term mort …
Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children.
Faustino EVS, Hirshberg EL, Asaro LA, Biagas KV, Pinto N, Srinivasan V, Bagdure DN, Steil GM, Coughlin-Wells K, Wypij D, Nadkarni VM, Agus MSD, Mourani PM, Chima R, Thomas NJ, Li S, Pinto A, Newth C, Hassinger A, Bysani K, Rehder KJ, Kandil S, Wintergerst K, Schwarz A, Marsillio L, Cvijanovich N, Pham N, Quasney M, Flori H, Federman M, Nett S, Viteri S, Schneider J, Medar S, Sapru A, McQuillen P, Babbitt C, Lin JC, Jouvet P, Yanay O, Allen C; Heart And Lung Failure-Pediatric INsulin Titration (HALF-PINT) Study Investigators. Faustino EVS, et al. Crit Care Med. 2019 May;47(5):706-714. doi: 10.1097/CCM.0000000000003699. Crit Care Med. 2019. PMID: 30789401
OBJECTIVES: Previous studies report worse short-term outcomes with hypoglycemia in critically ill children. These studies relied on intermittent blood glucose measurements, which may have introduced detection bias. We analyzed data from the Heart And Lung Failure-Pediatric …
OBJECTIVES: Previous studies report worse short-term outcomes with hypoglycemia in critically ill children. These studies relied on i …
Understanding the global epidemiology of pediatric critical illness: the power, pitfalls, and practicalities of point prevalence studies.
Weiss SL, Fitzgerald JC, Faustino EV, Festa MS, Fink EL, Jouvet P, Bush JL, Kissoon N, Marshall J, Nadkarni VM, Thomas NJ. Weiss SL, et al. Among authors: faustino ev. Pediatr Crit Care Med. 2014 Sep;15(7):660-666. doi: 10.1097/PCC.0000000000000156. Pediatr Crit Care Med. 2014. PMID: 24751790 Free PMC article. Review.
Studies screened up to 6,317 patients and reported data on prevalence and therapeutic variability. Three studies also reported short-term outcomes, a valuable but atypical data element in point prevalence studies. ...
Studies screened up to 6,317 patients and reported data on prevalence and therapeutic variability. Three studies also reported short-term …
Control of serum glucose concentration in critical illness.
Kandil SB, Miksa M, Faustino EV. Kandil SB, et al. Among authors: faustino ev. Curr Opin Pediatr. 2013 Jun;25(3):297-303. doi: 10.1097/MOP.0b013e328360c6a0. Curr Opin Pediatr. 2013. PMID: 23657243 Review.
There is also uncertainty about the generalizability of these results to nonpostoperative cardiac patients. There is only one published study addressing the long-term safety of TGC in children. In this study, hypoglycemia was not associated with adverse effects on neurocog …
There is also uncertainty about the generalizability of these results to nonpostoperative cardiac patients. There is only one published stud …
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