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COVID-19-Associated Acute Kidney Injury and Longitudinal Kidney Outcomes.
Aklilu AM, Kumar S, Nugent J, Yamamoto Y, Coronel-Moreno C, Kadhim B, Faulkner SC, O'Connor KD, Yasmin F, Greenberg JH, Moledina DG, Testani JM, Wilson FP. Aklilu AM, et al. Among authors: faulkner sc. JAMA Intern Med. 2024 Apr 1;184(4):414-423. doi: 10.1001/jamainternmed.2023.8225. JAMA Intern Med. 2024. PMID: 38407862
Although rapid kidney function decline has been reported in the first few months after COVID-19-associated AKI (COVID-AKI), the longer-term association of COVID-AKI with kidney function remains unknown. OBJECTIVE: To assess long-term kidney outcomes of patients who …
Although rapid kidney function decline has been reported in the first few months after COVID-19-associated AKI (COVID-AKI), the longer-te …
Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy.
Dowdell A, Marsland M, Faulkner S, Gedye C, Lynam J, Griffin CP, Marsland J, Jiang CC, Hondermarck H. Dowdell A, et al. Among authors: faulkner s. FASEB Bioadv. 2023 Mar 13;5(5):211-220. doi: 10.1096/fba.2022-00141. eCollection 2023 May. FASEB Bioadv. 2023. PMID: 37151848 Free PMC article.
GBM cells resistant to TMZ were also responsive to MKC-3946 and the long-term inhibitory effect of MKC-3946 was confirmed by colony formation assay. ...
GBM cells resistant to TMZ were also responsive to MKC-3946 and the long-term inhibitory effect of MKC-3946 was confirmed by colony f …
Remote care in UK general practice: baseline data on 11 case studies.
Greenhalgh T, Shaw SE, Alvarez Nishio A, Byng R, Clarke A, Dakin F, Faulkner S, Hemmings N, Husain L, Kalin A, Ladds E, Moore L, Rosen R, Rybczynska-Bunt S, Wherton J, Wieringa S. Greenhalgh T, et al. Among authors: faulkner s. NIHR Open Res. 2022 Nov 29;2:47. doi: 10.3310/nihropenres.13290.2. eCollection 2022. NIHR Open Res. 2022. PMID: 36814638 Free PMC article.
As the study unfolds, we will explore how practices achieve timely diagnosis of urgent or serious illness and manage continuity of care, long-term conditions and complex needs. We describe early results from the Remote by Default 2 study, which is following 11 UK general p …
As the study unfolds, we will explore how practices achieve timely diagnosis of urgent or serious illness and manage continuity of care, lon …
Protocol: Remote care as the 'new normal'?  Multi-site case study in UK general practice.
Greenhalgh T, Shaw SE, Alvarez Nishio A, Booth A, Byng R, Clarke A, Dakin F, Davies R, Faulkner S, Hemmings N, Husain L, Kalin A, Ladds E, Moore L, Rosen R, Rybczynska-Bunt S, Wherton J, Wieringa S. Greenhalgh T, et al. Among authors: faulkner s. NIHR Open Res. 2022 Aug 8;2:46. doi: 10.3310/nihropenres.13289.1. eCollection 2022. NIHR Open Res. 2022. PMID: 37881300 Free PMC article.
RESULTS ANTICIPATED: We expect to produce rich narratives of contingent change over time, addressing cross-cutting themes including access, triage and capacity; digital and wider inequities; quality and safety of care (e.g. continuity, long-term condition management, timel …
RESULTS ANTICIPATED: We expect to produce rich narratives of contingent change over time, addressing cross-cutting themes including access, …
Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
STARSurg Collaborative and EuroSurg Collaborative. STARSurg Collaborative and EuroSurg Collaborative. BJS Open. 2022 Jan 6;6(1):zrab150. doi: 10.1093/bjsopen/zrab150. BJS Open. 2022. PMID: 35179188 Free PMC article.
BACKGROUND: Postoperative acute kidney injury (AKI) is a common complication of major gastrointestinal surgery with an impact on short- and long-term survival. No validated system for risk stratification exists for this patient group. ...
BACKGROUND: Postoperative acute kidney injury (AKI) is a common complication of major gastrointestinal surgery with an impact on short- and …
A highly virulent variant of HIV-1 circulating in the Netherlands.
Wymant C, Bezemer D, Blanquart F, Ferretti L, Gall A, Hall M, Golubchik T, Bakker M, Ong SH, Zhao L, Bonsall D, de Cesare M, MacIntyre-Cockett G, Abeler-Dörner L, Albert J, Bannert N, Fellay J, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Laeyendecker O, Meyer L, Porter K, Ristola M, van Sighem A, Berkhout B, Kellam P, Cornelissen M, Reiss P, Fraser C; Netherlands ATHENA HIV Observational Cohort†; BEEHIVE Collaboration†. Wymant C, et al. Science. 2022 Feb 4;375(6580):540-545. doi: 10.1126/science.abk1688. Epub 2022 Feb 3. Science. 2022. PMID: 35113714 Free article.
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expected to be reached, on average, 9 months after diagnosis for individuals in their thirties with this variant. Age, sex, suspected mode of trans …
Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences-is expecte …
Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.
STARSurg Collaborative. STARSurg Collaborative. BJS Open. 2021 Nov 9;5(6):zrab134. doi: 10.1093/bjsopen/zrab134. BJS Open. 2021. PMID: 35029656 Free PMC article.
BACKGROUND: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has not been well characterized. ...
BACKGROUND: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has …
Achieving Spread, Scale Up and Sustainability of Video Consulting Services During the COVID-19 Pandemic? Findings From a Comparative Case Study of Policy Implementation in England, Wales, Scotland and Northern Ireland.
Shaw SE, Hughes G, Wherton J, Moore L, Rosen R, Papoutsi C, Rushforth A, Morris J, Wood GW, Faulkner S, Greenhalgh T. Shaw SE, et al. Among authors: faulkner s. Front Digit Health. 2021 Dec 20;3:754319. doi: 10.3389/fdgth.2021.754319. eCollection 2021. Front Digit Health. 2021. PMID: 34988546 Free PMC article.
Across all four nations ongoing uncertainty, potential restructuring and tightening of regulations, along with difficulties inherent in addressing inequalities in digital access, raise questions about the longer-term sustainability of changes to-date....
Across all four nations ongoing uncertainty, potential restructuring and tightening of regulations, along with difficulties inherent in addr …
Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis.
Maley MJ, Hunt AP, Stewart IB, Faulkner SH, Minett GM. Maley MJ, et al. Among authors: faulkner sh. PLoS One. 2019 Mar 22;14(3):e0214223. doi: 10.1371/journal.pone.0214223. eCollection 2019. PLoS One. 2019. PMID: 30901372 Free PMC article.
Likewise, a glucose challenge given within 24 hours of a single-bout of heating does not affect glucose tolerance in non-diabetic individuals. Despite the promise PH may hold, no short-term benefit to glucose tolerance is observed in non-diabetic individuals. ...
Likewise, a glucose challenge given within 24 hours of a single-bout of heating does not affect glucose tolerance in non-diabetic individual …
Prescribed opioids in primary care: cross-sectional and longitudinal analyses of influence of patient and practice characteristics.
Foy R, Leaman B, McCrorie C, Petty D, House A, Bennett M, Carder P, Faulkner S, Glidewell L, West R. Foy R, et al. Among authors: faulkner s. BMJ Open. 2016 May 13;6(5):e010276. doi: 10.1136/bmjopen-2015-010276. BMJ Open. 2016. PMID: 27178970 Free PMC article.
OBJECTIVES: To examine trends in opioid prescribing in primary care, identify patient and general practice characteristics associated with long-term and stronger opioid prescribing, and identify associations with changes in opioid prescribing. ...We excluded patients with …
OBJECTIVES: To examine trends in opioid prescribing in primary care, identify patient and general practice characteristics associated with l …
18 results